- Volume 41 Issue 2
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Effects of Cosmetics and Their Preservatives on the Growth and Composition of Human Skin Microbiota
피부 미생물총의 생장과 구성에 대한 화장품과 그 방부제의 영향
- Jeong, Jin-Ju (Department of Life and Nanopharmaceutical Sciences, Kyung Hee University) ;
- Kim, Dong-Hyun (Department of Life and Nanopharmaceutical Sciences, Kyung Hee University)
- Received : 2015.03.06
- Accepted : 2015.06.16
- Published : 2015.06.30
We investigated the growth-inhibitory activities of cosmetics and their preservatives against pathogens and resident skin bacteria. Of the tested cosmetics, preservatives such as parabens, 1,2-hexanediol, phenoxyethanol-contained toner, emulsion, cream and baby cream exhibited potent antibacterial effects against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Parabens, 1,2-hexanediol and phenoxyethanol inhibited the growth of pathogens, as well as skin-resident bacteria such as Staphilococcus epidermidis, Shigella flexneri, Enterobacter aerogenes and so on. The application of a basic cream containing phenoxyethanol to human skin was shown to disturb the skin microbiota: at the phylum level, Proteobacteria increased and at species level, 4P004125_s increased and Propionibacterium humerusii decreased. Based on these findings, parabens, 1,2-hexanediol and phenoxyethanol have antimicrobial activity and cosmetics containing phenoxyethanol may disturb skin microbiota.
cosmetic;preservative;skin microbiota;growth inhibition
Supported by : Ministry of Food and Drug Safety
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