DOI QR코드

DOI QR Code

Knowledge of Human Papillomavirus and its Association with Head and Neck Benign and Malignant Lesions in a Group of Dental Patients in Pakistan

  • Gichki, Abdul Samad (Department of Oral Medicine, Bolan Medical College) ;
  • Buajeeb, Waranun (Department of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University) ;
  • Doungudomdacha, Sombhun (Department of Conservative Dentistry, Faculty of Dentistry, Western University) ;
  • Khovidhunkit, Siribang-On Pibooniyom (Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University)
  • Published : 2015.03.09

Abstract

Human papillomaviruses (HPVs) remain a serious world health problem due to their association with cervical and head and neck cancers. While over 100 HPV types have been identified, only a few subtypes are associated with malignancies. HPV 16 and 18 are the most prevalent oncogenic types in head and neck cancers. Although it has been proven that some subsets of benign and malignant head and neck lesions are associated with HPV, the general population have very little awareness and knowledge of their association with HPV. Therefore, the purpose of this study was to determine the knowledge of HPV and its links with head and neck benign and malignant lesions in a group of Pakistani dental patients who attended the Dental Department of the Sandeman provincial hospital in Quetta, Pakistan. One hundred and ninety-two patients were recruited and requested to answer a questionnaire. It was revealed that there was a low level of knowledge about HPV and its association with head and neck benign and malignant lesions among the participants. This result suggested that more education regarding the relationship of HPV in inducing head and neck benign and malignant lesions is required in this group of patients.

Keywords

Human papilllomavirus;head and neck cancer;knowledge;Pakistani dental patients

Acknowledgement

Supported by : Mahidol University

References

  1. Brewer NT, Ng TW, McRee AL, Reiter PL (2010). Men's beliefs about HPV-related disease. J Behav Med, 33, 274-81. https://doi.org/10.1007/s10865-010-9251-2
  2. Caetano ME, Linhares IM, Pinotti JA, et al (2010). Sexual behavior and knowledge of sexually transmitted infections among university students in Sao Paulo, Brazil. Int J Gynaecol Obstet, 110, 43-6. https://doi.org/10.1016/j.ijgo.2010.02.012
  3. Carr J, Gyorfi T (2000). Human papillomavirus. Epidemiology, transmission and pathogenesis. Clin Lab Med, 20, 235-55.
  4. Chang F, Syrjanen S, Kellokoski J, Syrjanen K (1991). Human papillomavirus (HPV) infections and their associations with oral disease. J Oral Pathol Med, 20, 305-17. https://doi.org/10.1111/j.1600-0714.1991.tb00936.x
  5. Daley E, DeBate R, Dodd V, et al (2011). Exploring awareness, attitudes and perceived role among oral health providers regarding HPV-related oral cancers. J Public Health Dent, 71, 136-42. https://doi.org/10.1111/j.1752-7325.2011.00212.x
  6. Gerend MA, Magloire ZF (2008). Awareness, knowledge and beliefs about human papillomavirus in a racially diverse sample of young adults. J Adolesc Health, 42, 237-42. https://doi.org/10.1016/j.jadohealth.2007.08.022
  7. Gichki AS, Buajeeb , Doungudomdacha S, Khovidhunkit SP (2012). Detection of human papillomavirus in normal oral cavity in a group of Pakistani subjects using real-time PCR. Asian Pac J Cancer Prev, 13, 2299-304. https://doi.org/10.7314/APJCP.2012.13.5.2299
  8. Hoglund AT, Tyden T, Hannerfors AK, Larsson M (2009). Knowledge of human papillomavirus and attitudes to vaccination among Swedish high school students. Int J STD AIDS, 20, 102-7. https://doi.org/10.1258/ijsa.2008.008200
  9. Kobetz E, Kornfeld J, Vanderpool RC, et al (2010). Knowledge of HPV among United States Hispanic women: opportunities and challenges for cancer prevention. J Health Commun, 3, 22-9.
  10. Kojima A, Maeda H, Kurahashi N, et al (2003). Human papillomaviruses in the normal oral cavity of children in Japan. Oral Oncol, 39, 821-8. https://doi.org/10.1016/S1368-8375(03)00100-3
  11. Kulasingam SL, Hughes JP, Kiviat NB, et al (2002). Evaluation of human papillomavirus testing in primary screening for cervical abnormalities: comparison of sensitivity, specificity and frequency of referral. Jama, 288, 1749-57. https://doi.org/10.1001/jama.288.14.1749
  12. Montgomery K, Smith-Glasgow ME (2012). Human papillomavirus and cervical cancer knowledge, health beliefs and preventive practices in 2 age cohorts: a comparison study. Gend Med, 9, 55-66. https://doi.org/10.1016/j.genm.2011.11.002
  13. Prabhu SR, Wilson DF (2013). Human papillomavirus and oral disease-emerging evidence: a review. Aust Dent J, 58, 2-10.
  14. Reiter PL, Brewer NT, Smith JS (2010). Human papillomavirus knowledge and vaccine acceptability among a national sample of heterosexual men. Sex Transm Infect, 86, 241-6. https://doi.org/10.1136/sti.2009.039065
  15. Saha A, Chaudhury AN, Bhowmik P, Chatterjee R (2010). Awareness of cervical cancer among female students of premier colleges in Kolkata, India. Asian Pac J Cancer Prev, 11, 1085-90.
  16. Stock ML, Peterson LM, Houlihan AE, Walsh LA (2012). Influence of oral sex and oral cancer information on young adults' oral sexual-risk cognitions and likelihood of HPV vaccination. J Sex Res, 50, 95-102.
  17. Waller J, McCaffery K, Forrest S, et al (2003). Awareness of human papillomavirus among women attending a well woman clinic. Sex Transm Infect, 79, 320-2. https://doi.org/10.1136/sti.79.4.320
  18. Wierzbicka M, Jozefiak A, Jackowska J, Szydlowski J, Gozdzicka-Jozefiak (2014). A HPV vaccination in head and neck HPV-related pathologies. Otolaryngol Pol, 68, 157-73. https://doi.org/10.1016/j.otpol.2014.05.004