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Effects of 915 MHz Radiofrequency Identification Electromagnetic Field Exposure on Neuronal Precursor Cells in the Dentate Gyrus of Adult Rat Brains

  • Kim, Hye Sun (Department of Neurosurgery, School of Medicine, Ajou University) ;
  • Lee, Yu Hee (Department of Neurosurgery, School of Medicine, Ajou University) ;
  • Lee, Yun-Sil (Division of Life Science and Pharmaceuticals, College of Pharmacy, Ewha Woman's University) ;
  • Choi, Hyung-Do (Department of Radio Technology Research, Electronics and Telecommunications Research Institute) ;
  • Kwon, Jong Hwa (Department of Radio Technology Research, Electronics and Telecommunications Research Institute) ;
  • Pack, Jeong-Ki (Department of Radio Sciences and Engineering, College of Engineering, Chungnam National University) ;
  • Kim, Nam (School of Electrical and Computer Engineering, Chungbuk National University) ;
  • Ahn, Young Hwan (Department of Neurosurgery, School of Medicine, Ajou University)
  • Received : 2015.05.26
  • Accepted : 2015.07.06
  • Published : 2015.07.31

Abstract

To explore the effects of radiofrequency electromagnetic field on the fate of neuronal cells, we investigated whether exposure to 915 MHz radiofrequency identification (RFID) caused morphological changes in neuronal cells in rat hippocampal dentate gyrus (DG). A reverberation chamber was used as a whole-body RFID exposure system. Rats were assigned to two groups: sham- and RFID-exposed groups. Rats in the RFID-exposed group were exposed to RFID at 4 W/kg specific absorption rate (SAR) for 8 hours daily, 5 days per week, for 2 weeks. Morphological evaluation of DG was performed using immunohistochemistry with doublecortin (DCX) as a neuronal precursor cell marker and neuronal nuclei (NeuN) as a mature neuronal cell marker. No significant morphological changes in DCX+ or NeuN+ cells in the DG of RFID-exposed rats were observed. These results suggest that RFID exposure induces no significant change in DCX+ neuronal precursor or NeuN+ neuronal cells in DG of rats.

Keywords

915 MHz RFID;DCX;Dentate Gyrus;NeuN

Acknowledgement

Grant : Study on the EMF exposure control in smart society

Supported by : IITP

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