- Volume 16 Issue 1
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Kidney Cancer in Lebanon: a Specific Histological Distribution?
- Khafaja, Sarah (Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University) ;
- Kourie, Hampig Raphael (Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University) ;
- Matar, Dany (Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University) ;
- Sader-Ghorra, Claude (Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University) ;
- Kattan, Joseph (Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University)
- Published : 2015.02.04
Background: Kidney cancer is the third most frequent urologic cancer in Lebanon after prostate and bladder cancer, accounting for 1.5% of all diagnosed cancers. In this paper, we report the histologic characteristics and distribution of kidney cancer, never described in Lebanon or the Middle East. Materials and Methods: Pathology results of operated kidney cancer were collected during a two year period (2010-2011) from two different Lebanese hospitals (Hotel-Dieu de France University Hospital and Saint Joseph Hospital). A total of 124 reports were reviewed and analyzed according to WHO classification of 2009. Results: The 124 patients diagnosed with kidney cancer had a median age of 62.4 [18-86], 75% being men and 25% women. Some 71 % of the lesions were renal cell carcinoma (RCC), 25.8% had a urothelial histology, 1.6% were lymphomas and 1.6% were metastases to the kidney. Patients having RCC had a median age of 60.3 [18-85], 77.3% were men and 22.7% women. Of the RCCs, 59.1% were clear cell carcinoma, 22.7% papillary, 11.4% chromophobic, 3.4% rom the collecting ducts of Bellini and 3.4% were not otherwise classified. Conclusions: Histological distribution of Lebanese kidney cancer seems unusual when compared to the literature. The percentage of urothelial renal pelvis tumors is strikingly high. Moreover, clear cell carcinoma accounts for only 59.1% of RCCS in contrast to the 75% described elsewhere, while papillary carcinoma represents more than 22.7% compared to 10%.
Kidney cancer;cancer epidemiology;renal pelvis tumor;clear cell carcinoma
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