- Volume 15 Issue 23
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Survival Time and Molecular Subtypes of Breast Cancer after Radiotherapy in Thailand
- Kongsiang, Apichat (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
- Tangvoraphonkchai, Vorachai (Department of Radiology, Faculty of Medicine, Khon Kaen University) ;
- Jirapornkul, Chananya (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
- Promthet, Supannee (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
- Kamsa-ard, Siriporn (Department of Biostatistics and Demography, Faculty of Public Health, Khon Kaen University) ;
- Suwanrungruang, Krittika (Cancer Unit, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University)
- Published : 2015.01.06
Background: Breast cancer is an important cause of death among women. One way of classifying different forms of breast cancer is by molecular features, usually in terms of the four subtypes: luminal A, luminal B, HER2-enriched, and triple negative. Objectives: This study aimed to investigate the association between molecular subtypes and survival among breast cancer patients treated with radiotherapy. Materials and Methods: A retrospective cohort study was conducted. The subjects were 272 breast cancer patients who had received treatment in the radiotherapy unit at Srinagarind Hospital, Thailand, between 1 January, 1999, and 31 May, 2009. The end of the study was 1 June, 2014. Overall survival was defined as the time elapsing between initial registration at the radiotherapy unit and death or the end of the study. Survival curves were estimated by the Kaplan-Meier method, and a multivariate analysis was performed using Cox's proportional hazard regression model. Results: The patient mean age was
Breast cancer;survival;molecular subtypes;radiotherapy
Supported by : Khon Kaen University
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