- Volume 15 Issue 23
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A Retrospective Multicenter Evaluation of Cutaneous Melanomas in Turkey
- Gamsizkan, Mehmet (Department of Pathology, Maresal Cakmak Military Hospital) ;
- Yilmaz, Ismail (GATA Haydarpasa Education and Research Hospital) ;
- Buyukbabani, Nesimi (Istanbul Medical School, Istanbul University) ;
- Demirkesen, Cuyan (Cerrahpasa Medical School, Istanbul University) ;
- Demiriz, Murat (School of Medicine, Gulhane Military Medical Academy) ;
- Cetin, Emel Dikicioglu (Acibadem Kadikoy Hospital) ;
- Ince, Umit (School of Medicine, Acibadem University) ;
- Akalin, Taner (School of Medicine, Ege University) ;
- Demirkan, Nese Calli (School of Medicine, Pamukkale University) ;
- Lebe, Banu (School of Medicine, Dokuz Eylul University) ;
- Erdem, Ozlem (School of Medicine, Gazi University) ;
- Gokoz, Ozay (School of Medicine, Hacettepe University) ;
- Sakiz, Damlanur (Bakirkoy Dr. Sadi Konuk Education and Research Hospital) ;
- Demireli, Peyker Temiz (School of Medicine, Celal Bayar University) ;
- Astarci, Hesna Muzeyyen (School of Medicine, Abant Izzet Baysal University) ;
- Adim, Saduman Balaban (School of Medicine, Uludag University) ;
- Zemheri, Itir Ebru (Goztepe Education and Research Hospital, Medeniyet University) ;
- Acikalin, Arbil (School of Medicine, Cukurova University) ;
- Yaman, Banu (School of Medicine, Ege University) ;
- Aydin, Ovgu (Cerrahpasa Medical School, Istanbul University) ;
- Bassorgun, Cumhur Ibrahim (School of Medicine, Akdeniz University)
- Published : 2015.01.06
Background: We defined melanoma distribution in a large series of Turkish patients and evaluated the prognostic parameters of melanomas. Materials and Methods: A total of 1574 patients' data was retrospectively collected at 18 centers in Turkey. Demographic characteristics were questioned and noted. Prognostic parametres were evaluated based on sentinel lymph node involvement. Results: Mean age was 56.7 (4-99) years. While 844 (53.6%) cases were male, 730 (46.4%) cases were female. One thousand four hundred forty-seven (92%) cases were invasive melanoma and 127 (8%) cases were in-situ melanoma. The most common histopathological form was the superficial spreading melanoma (SSM) which was found in 549 patients (37.9%). It was followed by nodular melanoma in 379 (26.2%), acral lentiginous melanoma (ALM) in 191 (13.2%) and lentigo maligna melanoma in 132 (9.1%), respectively. On univariate analysis, lymphovascular invasion (p<0.001), tumor thickness (p<0.001), histopathological subtype (p<0.001), Clark level (p=0.001), ulceration (p<0.001),
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