DOI QR코드

DOI QR Code

Red Meat Intake and Risk of Non-Hodgkin Lymphoma: A Meta-Analysis

  • Fallahzadeh, Hosein (Department of Biostatistics and Epidemiology, Research Center of Prevention and Epidemiology of Non-Communicable Disease, Faculty of Health, Shahid Sadoughi University of Medical Sciences) ;
  • Cheraghi, Maria (Social Determinants of Heath Research Center, School of Public Heath, Ahvaz Jundishapour University of Medical Sciences) ;
  • Amoori, Neda (Department of Biostatic and Epidemiology, Abadan School of Medical Sciences) ;
  • Alaf, Mehrangiz (Biochemistry, Health Office, Abadan School of Medical Sciences)
  • Published : 2015.01.06

Abstract

Background: While the incidence of non-Hodgkins lymphoma (NHL) has been rising worldwide, the reasons remain undefined. Recent research has focused on effect of red andf processed meat intake as a risk factor, but with inconclusive results. We therefore conducted a meta-analysis of data published to date, to ascertain the overall association between intake and NHL. Materials and Methods: A published literature search was performed through Pubmed, Cochrane Library, Medline, and Science Citation Index Expanded databases for articles published in English. Pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) were calculated using random or fixed effects models. Heterogeneity was assessed using Chi-square and I2 statistics. Dissemination bias was evaluated by funnel plot analysis.We performed a formal meta-analysis using summary measures from these studies. Results: In total, 11 published studies were included in the final analysis. The combined analysis revealed that there was significant association between the red meat and NHL risk (OR=1.10, 95%CI: 1.02 to 1.19, p=0.01). Additionally, there was showed significance association between processed red meat and NHL risk (OR=1.17, 95%CI: 1.06 to 1.29, p=0.001). In subgroup analysis, a statistical significant association was noted between diffuse large B-cell lymphoma (DLBCL) (OR=1.20, 95%CI: 1.04 to 2.37, P=0.01) and red meat intake. Conclusions: In this meta-Analysis, there was evidence for association between consumption of red meat, or processed meat and risk of NHL, particularly with the DLBCL subtype in the red meat case.

References

  1. Binesh F, Akhavan A, Behniafard N, Atefi A(2014). Clinicopathologic and survival characteristics of childhood and adolescent non-Hodgkin's lymphoma in Yazd, Iran. Asian Pac J Cancer Prev, 15, 1585-8. https://doi.org/10.7314/APJCP.2014.15.4.1585
  2. Calder PC, Grimble RF (2002). Polyunsaturated fatty acids, inflammation and immunity. Eur J Clin Nutr, 56, 14-9 https://doi.org/10.1038/sj.ejcn.1601478
  3. Chang ET, Balter KM, Torrang A, et al (2006). Nutrient intake and risk of non-Hodgkin's lymphoma. Am J Epidemiol, 164, 1222-32. https://doi.org/10.1093/aje/kwj330
  4. Chiu BC, Cerhan JR, Folsom AR, et al (1996). Diet and risk of non-Hodgkin lymphoma in older women. JAMA, 275, 1315-21. https://doi.org/10.1001/jama.1996.03530410029029
  5. Cross AJ, Ward MH, Schenk M, et al (2006). Meat and meatmutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control study. Carcinogenesis, 27, 293-7. https://doi.org/10.1093/carcin/bgi212
  6. Daniel CR, Sinha R, Park Y, et al (2012). Meat intake is not associated with risk of non-hodgkin lymphoma in a large prospective cohort of US men and women. J Nutrition, 142, 1074-80. https://doi.org/10.3945/jn.112.158113
  7. Davis S (1992). Nutritional factors and the development of non-Hodgkin's lymphoma: a review of the evidence. Cancer Res, 52, 5492-5.
  8. Amanat A, Al-Belushi B, Waly M, Al-Moundhri M, Burney Ik (2013). Dietary and lifestyle factors and risk of non-Hodgkin's lymphoma in Oman. Asian Pac J Cancer Prev, 14, 841-8. https://doi.org/10.7314/APJCP.2013.14.2.841
  9. Amoori N, Mirzaei M, Cheraghi M(2014). Incidence of cancers in kuzestan province of Iran: Trend from 2004 to 2008. Asian Pac J Cancer Prev, 15, 8345-9. https://doi.org/10.7314/APJCP.2014.15.19.8345
  10. Erber E, Maskarinec G, Gill JK, Park S-Y, Kolonel LN (2009). Dietary patterns and the risk of non-Hodgkin lymphoma: the Multiethnic Cohort. Leukemia Lymphoma, 50, 1269-75. https://doi.org/10.1080/10428190903030841
  11. Kabat GC, Kim MY, Wactawski-Wende J, et al (2012). Anthropometric factors, physical activity and risk of Nonhodgkin's lymphoma in the women's health initiative. Cancer Epidemiology, 36, 52-9. https://doi.org/10.1016/j.canep.2011.05.014
  12. Karami K, Cheraghi M, Amori N, Pedram M, Sobhani A(2014). Common Cancers in Khuzestan Province, South West of Iran, during 2005-2011. Asian Pac J Cancer Prev: APJCP, 15, 9475-8 https://doi.org/10.7314/APJCP.2014.15.21.9475
  13. Kilfoy B, Nicholas J, Kolar Ca, et al (2012). Meat intake and risk of non-Hodgkin lymphoma. Cancer Causes Control, 23, 1681-92. https://doi.org/10.1007/s10552-012-0047-2
  14. Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB (2003). Cancer Incidence in Five Continents.
  15. Polesel J, Talamini R, Montella M et al (2006). Linoleic acid,vitamin D and other nutrient intakes in the risk of non-Hodgkin lymphoma: an Italian case-control study. Ann Oncol, 17, 713-8. https://doi.org/10.1093/annonc/mdl054
  16. Purdue MP, Bassani DG, Klar NS, Sloan M, Kreiger N(2004). Dietary factors and risk of non-Hodgkin lymphoma by histologic subtype: a case-control analysis. Cancer Epidemiol Biomarkers Prev, 13, 1665-76.
  17. Rohrmann S, Linseisen J, Jakobsen MU, et al(2011). Consumption of meat and dairy and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition. Int J Cancer, 128, 623-34. https://doi.org/10.1002/ijc.25387
  18. Salim EI, Jazieh AR, Moore MA (2011). Lung cancer incidence in the Arab league countries; risk factors and control. Asian Pac J Cancer Prev, 12, 17-34.
  19. Sangrajrang S, Renard H, Kuhaprema T, et al (2011). Personal use of hair dyes - increased risk of non-Hodgkin's lymphoma in Thailand. Asian Pac J Cancer Prev, 12, 2393-6.
  20. Stefani E, Ronco AL, Deneo-Pellegrini H, et al (2013). Meat, milk and risk of lymphoid malignancies: a case-control study in Uruguay. Nutrition Cancer, 65, 375-83 https://doi.org/10.1080/01635581.2013.761255
  21. Talamini R, Polesel J, Montella M, Dal Maso L, Crovatto M, Crispo A, et al (2006). Food groups and risk of non Hodgkin lymphoma: A multicenter, case control study in Italy. Int J Cancer, 118, 2871-6. https://doi.org/10.1002/ijc.21737
  22. Yaqoob P (2002). Monounsaturated fatty acids and immune function. Eur J Clin Nutr, 56, 9-13. https://doi.org/10.1038/sj.ejcn.1601477
  23. Yildirim M, Karakilinc H, Yildiz M, et al (2013). Non-hodgkin lymphoma and pesticide exposure in Turkey. Asian Pacific J Cancer Prev, 14, 3461-3. https://doi.org/10.7314/APJCP.2013.14.6.3461
  24. Zekri AR, Hassan ZK, Bahnassy AA et al (2013). Gene expression profiling of non-Hodgkin lymphomas. Asian Pac J Cancer Prev, 14, 4393-8. https://doi.org/10.7314/APJCP.2013.14.7.4393
  25. Zhang S, Hunter DJ, Rosner BA, et al (1999). Dietary fat and protein in relation to risk of non-Hodgkin's lymphoma among women. J National Cancer Institute, 91, 1751-8. https://doi.org/10.1093/jnci/91.20.1751
  26. Zheng T, Holford TR, Leaderer B, et al (2004). Diet and nutrient intakes and risk of non-Hodgkin's lymphoma in Connecticut women. Am J Epidemiol, 159, 454-66. https://doi.org/10.1093/aje/kwh067

Cited by

  1. Epidemiology and trend of common cancers in Iran (2004-2008) vol.26, pp.5, 2016, https://doi.org/10.1111/ecc.12449
  2. Red meat, diseases, and healthy alternatives: A critical review pp.1549-7852, 2016, https://doi.org/10.1080/10408398.2016.1158148
  3. A summary of meat intakes and health burdens pp.1476-5640, 2017, https://doi.org/10.1038/ejcn.2017.117
  4. Dairy Product Consumption and Risk of Non-Hodgkin Lymphoma: A Meta-Analysis vol.8, pp.3, 2016, https://doi.org/10.3390/nu8030120