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A Study on Mice Exposure Dose for Low-dose Gamma-irradiation Using Glass Dosimeter

유리선량계를 이용한 저선량 방사선의 마우스 피폭선량 연구

  • Noh, Sung Jin (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Kim, Hyo Jin (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Kim, Hyun (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Jeong, Dong Hyeok (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Son, Tae Gen (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Kim, Jung Ki (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Yang, Kwangmo (Research Center, Dongnam Institute of Radiological & Medical Sciences) ;
  • Nam, Sang-Hee (Department of Biomedical Engineering, Inje University) ;
  • Kang, Yeong-Rok (Research Center, Dongnam Institute of Radiological & Medical Sciences)
  • Received : 2015.07.29
  • Accepted : 2015.11.10
  • Published : 2015.12.31

Abstract

The low dose radiation is done for a long period, thus researchers have to know the exact dose distribution for the irradiated mouse. This research has been conducted in order to find out methods in transmitting an exact dose to mouse in a mouse irradiation experiment carried out using $^{137}Cs$ irradiation equipment installed in the DIRAMS (Dongnam Institution of Radiological & Medical Sciences) research center. We developed a single mouse housing cage and shelf with adjustable geometric factors such as distance and angle from collimator. The measurement of irradiated dose showed a maximal 42% difference of absorbed dose from the desired dose in the conventional irradiation system, whereas only 6% difference of the absorbed dose was measured in the self-developed mouse apartment system. In addition, multi mice housing showed much difference of the absorbed dose in between head and body, compared to single mouse housing in the conventional irradiation system. This research may allow further research about biological effect assessment for the low dose irradiation using the self-developed mouse apartment to provide more exact doses which it tries to transmit, and to have more reliability for the biological analysis results.

저선량 조사는 낮은 선량을 지속적으로 장기간 조사시키기 때문에 조사되는 마우스들에 대한 선량분포를 정확히 알고 있어야만 한다. 본 연구는 저선량 방사선에 대한 생물학적 영향평가를 위하여 동남권원자력의학원 연구센터에 설치된 $^{137}Cs$ 조사장치에 대하여 마우스조사 실험 시 마우스에 원하고자 하는 선량을 전달하기 위한 방법에 대하여 연구를 수행하였다. 마우스에 원하고자 하는 정확한 선량을 전달하기 위하여 선원에 대하여 동일한 위치에 마우스 케이지 45개를 설치할 수 있는 아파트를 자체 개발하였으며, 개발된 마우스 아파트 시스템에 대한 선량평가를 하기 위하여 유리선량계(glass dosimeter)를 실험용 마우스 머리와 배에 삽입한 후 기존 조사 시스템과 자체 개발한 마우스 아파트 시스템에 대해 비교 선량평가를 수행하였다. 기존시스템의 조사방식에서 최대 42%의 선량차이를 보였으며 개발한 마우스 아파트 시스템은 6% 이내의 선량차이를 보였다. 본 연구를 통해 개발된 마우스 아파트를 활용한 저선량 방사선에 대한 생물학적 영향평가 연구는 전달하고자 하는 선량을 보다 정확하게 제공할 수 있으며, 생물학적 분석결과에 신뢰성을 확보할 수 있다.

Keywords

Acknowledgement

Supported by : Dong-nam Institute of Radiological & Medical Sciences(DIRAMS)

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