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Mineral Metabolism in Singleton and Twin-pregnant Dairy Goats

  • Harter, C.J. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Castagnino, D.S. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Rivera, A.R. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Lima, L.D. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Silva, H.G.O. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Mendonca, A.N. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Bonfim, G.F. (Department of Animal Sciences, UNESP, Univ Estadual Paulista) ;
  • Liesegang, A. (Institute of Animal Nutrition, University of Zurich) ;
  • St-Pierre, N. (Department of Animal Sciences, The Ohio State University) ;
  • Teixeira, I.A.M.A. (Department of Animal Sciences, UNESP, Univ Estadual Paulista)
  • Received : 2014.03.25
  • Accepted : 2014.06.24
  • Published : 2015.01.01

Abstract

During pregnancy, the maternal body undergoes significant physiological changes. The present study assessed the changes on calcium (Ca), phosphorus (P), magnesium (Mg), sodium (Na) and potassium (K) metabolism in singleton and twin-pregnant dairy goats. The 42 goats used ($49.5kg{\pm}7.6$ body weight [BW]) were assigned at random to treatments that were factorially arranged to account for 2 breeds (Oberhasli and Saanen), 2 pregnancy types (singleton and twin) and 3 gestation periods (80, 110, and 140 days). Digestibility trials were performed at 80, 110, and 140 days of gestation. Mineral retention during pregnancy was determined in the maternal body, femur, uterus, mammary gland, fetus and fetal fluid. Blood samples were taken during pregnancy before and after a meal, and Ca, P, Mg, Na, K ions and alkaline phosphatase activity determined in serum. Bone mineral density was determined in the right femur. Statistical analyses were performed using the SAS MIXED procedure. Dry matter intake decreased linearly up to 140 days of gestation. Maternal BW gain, and Ca, P, and Mg retention (g/kg) decreased linearly with the advance of gestation days. Macromineral retention in maternal body (g/kg) was greater in Oberhasli than Saanen goats, and their fetuses had higher Ca, P, and Mg deposition (mg/g). Mineral retention (mg/g) increased in fetuses according to pregnancy development, with no differences between singleton and twin pregnancy. In the mammary gland, the retention of all minerals (g) increased with the days of pregnancy. In conclusion, related to Ca, P, and Mg metabolism can be divided into two stages. Up to 80 days of gestation, was characterized by the preparation of the maternal body reserves for future mineral demands. From 80 days of gestation onward, was characterized by the transfer of maternal body reserves for fetal development and colostrum production. Na and K supply was provided by adjustments in endogenous excretion and an increase in intestinal absorption. Finally, mineral metabolism was specific to each genotype and, except for Na, was not affected by the number of fetuses.

Keywords

Fetuses;Genotype;Maternal Body Reserves;Mineral Retention

Acknowledgement

Supported by : FAPESP

References

  1. AOAC. 1990. Official Methods of Analysis. 15th edn. Association of Official Analytical Chemists, Arlington, VA, USA.
  2. Etheridge, R. D., G. M. Pesti, and E. H. Foster. 1998. A comparison of nitrogen values obtained utilizing the Kjeldahl nitrogen and Dumas combustion methodologies (Leco CNS 2000) on samples typical of an animal nutrition analytical laboratory. Anim. Feed Sci. Technol. 73:21-28. https://doi.org/10.1016/S0377-8401(98)00136-9
  3. Araujo, M. J., A. N. Medeiros, I. A. M. A. Teixeira, R. G. Costa, S. M. B. Artoni, C. A. T. Marques, and K. T. Resende. 2011. Femur biometry, densitometry and chemical composition from Moxoto goats supplemented with concentrate in a semiarid region. Small Rumin. Res. 97:60-66. https://doi.org/10.1016/j.smallrumres.2011.02.012
  4. Bell, A. W., P. L. Greenwood, and R. A. Ehrhardt. 2005. Regulation of metabolism and growth during prenatal life. In:Biology of Metabolism in Growing Animals (Eds. D. G. Burrin and H. J. Mersmann). 3:3-34.
  5. Challis, J. R. G. and J. L. Linzell. 1971. The concentration of total unconjugated oestrogens in the plasma of pregnant goats. J. Reprod. Fertil. 26:401-404. https://doi.org/10.1530/jrf.0.0260401
  6. Csapo, J., Z. Csapo-Kiss, T. G. Martin, J. Szentpeteri, and G. Wolf. 1994. Composition of colostrum from goats, ewes, and cows producing twins. Int. Dairy J. 4:445-458. https://doi.org/10.1016/0958-6946(94)90058-2
  7. Fritz, J. S. and G. H. Schenk. 1979. Quantitative Analytical Chemistry. 4th ed. Allyn and Bacon, University of Michigan, Ann Arbor, MI, USA. 661 p.
  8. Hadjidakis, D. J. and I. I. Androulakis. 2006. Bone remodeling. Ann. NY Acad. Sci. 1092:385-396. https://doi.org/10.1196/annals.1365.035
  9. Haenlein, G. F. W. 1996. Status and prospects of the dairy goat industry in the United States. J. Anim. Sci. 74:1173-1181.
  10. Hosking, D. J. 1996. Calcium homeostasis in pregnancy. Clin. Endocrinol. 45:1-6. https://doi.org/10.1111/j.1365-2265.1996.tb02052.x
  11. House, W. A. and A. W. Bell. 1993. Mineral accretion in the fetus and adnexa during late gestation in Holstein cows. J. Dairy Sci. 76:2999-3010. https://doi.org/10.3168/jds.S0022-0302(93)77639-0
  12. Lehmann, F. G. 1975. Immunological methods for human placental alkaline phosphatase (Regan isoenzyme). Clin. Chim. Acta. 65:271-282. https://doi.org/10.1016/0009-8981(75)90252-1
  13. Irano, N., A. B. Bignardi, F. S. B. Rey, I. A. M. A. Teixeira, and L. G. Albuquerque. 2012. Genetic parameters for milk yield in Saanen and Alpina breed goats. Rev. Cienc. Agron. 43:376-381. https://doi.org/10.1590/S1806-66902012000200022
  14. Kovacs, C. S. 2001. Calcium and bone metabolism in pregnancy and lactation. Endocr. Rev. 86:2344-2348.
  15. Kovacs, C. S. 2003. Fetal Mineral Homeostasis. In: Pediatric Bone: Biology and Diseases (Eds. F. H. Glorieux, J. M. Pettifor, and H. Juppner). Academic Press, San Diego, CA, USA, pp. 271-302.
  16. Liesegang, A., J. Risteli, and M. Wanner. 2006. The effects of first gestation and lactation on bone metabolism in dairy goats and milk sheep. Bone 38:794-802. https://doi.org/10.1016/j.bone.2005.11.006
  17. Lima, L. D., G. V. Kozloski, L. M. Bonnecarrere Sanchez, A. P. Ruggia Chiesa, C. J. Harter, G. Fiorentini, L. Oliveira, and R. L. Cadorin Jr. 2008. Effect of harvesting period on the nutritive value of rice grass (Echinochloa sp.) hay given as sole diet to lambs. Small Rumin. Res. 75:217-225. https://doi.org/10.1016/j.smallrumres.2007.11.005
  18. Mattison, D. R., E. Blann, and A. Malek. 1990. Physiological alterations during pregnancy: Impact on toxicokinetics. Symposium: pharmacokinetics in developmental toxicity. Fundam. Appl. Toxicol. 16:215-218.
  19. National Research Council. 2007. Nutrient Requirements of Small Ruminants. Sheep, Goats, Cervids and New World Camelids. National Academy Press. Washington, DC, USA.
  20. Picciano, M. F. 2003. Pregnancy and lactation: Physiological adjustments, nutritional requirements and the role of dietary supplements. J. Nutr. 133:1997S-2002S.
  21. Pulina, G., A. Nudda, G. Battacone, S. Fancellu, and A. H. D. Francesconi. 2008. Nutrition and quality of goat's milk. In:Dairy Goats Feeding And Nutrition (Ed. A. H. D. Francesconi). CABI International. Wallingford, UK. pp.1-30.
  22. Suttle, N. F. 2010. The mineral nutrition of livestock. 4th ed. CABI International. Wallingford, UK.
  23. Ritar, A. J., W. C. M. Maxwell, and S. Salamon. 1984. Ovulation and LH secretion in the goat after intravaginal progestogen sponge-PMSG treatment. J. Reprod. Fertil. 72:559-563. https://doi.org/10.1530/jrf.0.0720559
  24. Robertson, J. B. and P. J. Van Soest. 1981. The detergent system of analysis and its application to human foods. In: The Analysis of Dietary Fiber in Food (Eds. W. P. T. James and O. Theander). Marcel Dekker, New York, USA. pp. 123-158.
  25. Scheaffer, A. N., J. S. Caton, M. L. Bauer, and P. Reynolds. 2001. Influence of pregnancy on body weight, ruminal characteristics, and visceral organ mass in beef heifers. J. Anim. Sci. 79:2481-2490.
  26. Tabatabaei, S. 2011. Gestational variations in the biochemical composition of the fetal fluids and maternal blood serum in goat. Comp. Clin. Pathol. DOI 10.1007/s00580-011-1286-4 https://doi.org/10.1007/s00580-011-1286-4
  27. Teixeira, I. A. M. A., K. T. de Resende, A. M. A. Silva, A. G. Silva Sobrinho, C. J. Härter, and A. P. O. Sader. 2013. Mineral requirements for growth of wool and hair lambs. Rev. Bras. Zootec. 42:347-353. https://doi.org/10.1590/S1516-35982013000500007
  28. Westhuysen, J. M. van der. 1979. The control of ovarian function in cycling and anestrus angora goat does. Agroanimalia, Pretoria. 11:23-25.
  29. Yildiz, A., E. Balikci, and F. Gurdogan. 2005. Serum mineral levels at pregnancy and postpartum in single and twin pregnant sheep. Biol. Trace Elem. Res. 107:247-254. https://doi.org/10.1385/BTER:107:3:247