Foot-and-mouth disease: overview of motives of disease spread and efficacy of available vaccines

  • Saeed, Ali (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Kanwal, Sehrish (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Arshad, Memoona (National Institute for Biotechnology and Genetic Engineering, (NIBGE)) ;
  • Ali, Muhammad (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Shaikh, Rehan Sadiq (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Abubakar, Muhammad (National Veterinary Laboratory)
  • Received : 2014.11.10
  • Accepted : 2015.01.16
  • Published : 2015.04.30


Control and prevention of foot and mouth disease (FMD) by vaccination remains unsatisfactory in endemic countries. Indeed, consistent and new FMD epidemics in previously disease-free countries have precipitated the need for a worldwide control strategy. Outbreaks in vaccinated animals require that a new and safe vaccine be developed against foot and mouth virus (FMDV). FMDV can be eradicated worldwide based on previous scientific information about its spread using existing and modern control strategies.


Attenuated virus;Foot-and-mouth disease;In-activated virus;Recombinant virus;Transgenic vaccines


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