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Foot-and-mouth disease: overview of motives of disease spread and efficacy of available vaccines

  • Saeed, Ali (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Kanwal, Sehrish (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Arshad, Memoona (National Institute for Biotechnology and Genetic Engineering, (NIBGE)) ;
  • Ali, Muhammad (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Shaikh, Rehan Sadiq (Instituteof Molecular Biology and Biotechnology, Bahauddin Zakariya University) ;
  • Abubakar, Muhammad (National Veterinary Laboratory)
  • Received : 2014.11.10
  • Accepted : 2015.01.16
  • Published : 2015.04.30

Abstract

Control and prevention of foot and mouth disease (FMD) by vaccination remains unsatisfactory in endemic countries. Indeed, consistent and new FMD epidemics in previously disease-free countries have precipitated the need for a worldwide control strategy. Outbreaks in vaccinated animals require that a new and safe vaccine be developed against foot and mouth virus (FMDV). FMDV can be eradicated worldwide based on previous scientific information about its spread using existing and modern control strategies.

Keywords

Attenuated virus;Foot-and-mouth disease;In-activated virus;Recombinant virus;Transgenic vaccines

References

  1. Mort M, Convery I, Baxter J, Bailey C. Psychosocial effects of the 2001 UK foot and mouth disease epidemic in a rural population: qualitative diary based study. BMJ. 2005;331:1234. https://doi.org/10.1136/bmj.38603.375856.68
  2. Rodriguez LL, Grubman MJ. Foot and mouth disease virus vaccines. Vaccine. 2009;4(Supplement 4):D90-4.
  3. Gibbs P. The foot-and-mouth disease epidemic of 2001 in the UK: implications for the USA and the "war on terror". J Vet Med Educ. 2003;30:121-32. https://doi.org/10.3138/jvme.30.2.121
  4. Sumption K, Rweyemamu M, Wint W. Incidence and distribution of foot-and-mouth disease in Asia, Africa and South America; combining expert opinion, official disease information and livestock populations to assist risk assessment. Transbound Emerg Dis. 2008;55:5-13. https://doi.org/10.1111/j.1865-1682.2007.01017.x
  5. Anonymous. Foot-and-mouth disease. In: Manual of diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees). Paris, France: World Organization for Animal Health (OIE); 2008.
  6. Doel TR, Williams L, Barnett PV. Emergency vaccination against foot-andmouth disease: rate of development of immunity and its implications for the carrier state. Vaccine. 1994;12:592-600. https://doi.org/10.1016/0264-410X(94)90262-3
  7. Abubakar M, Khan E, Arshed MJ, Hussain M, Ali Q, Afzal M. Mortality rate in association with foot and mouth disease outbreaks in cattle and buffaloes, Pakistan. ASM Sci J. 2013;7(2):139-43.
  8. Rodriguez LL, Gay CG. Development of vaccines toward the global control and eradication of foot-and-mouth disease. Expert Rev Vaccines. 2011;10:377-87. https://doi.org/10.1586/erv.11.4
  9. Dus Santos MJ, Wigdorovitz A. Transgenic plants for the production of veterinary vaccines. Immunol Cell Biol. 2005;83:229-38. https://doi.org/10.1111/j.1440-1711.2005.01338.x
  10. Seneque S Foot-and-Mouth Disease Control in Asia. Meeting Unique Challenges. in Proceedings of the Proceedings of 5th Asian Pig Veterinary Society Congress Pattaya, Thailand. 2011.
  11. Correa Melo E, Saraiva V, Astudillo V. Review of the status of foot and mouth disease in countries of South America and approaches to control and eradication. Rev Sci Tech. 2002;21:429-36. https://doi.org/10.20506/rst.21.3.1350
  12. OIE. WAHID Interface OIE World Animal Health Information Database. 2011. http://www.wrlfmd.org/ref_labs/ref_lab_reports/OIE-FAO%20FMD%20Ref%20Lab%20Report%20Jan-Mar%202011.pdf.
  13. Bergmann IE, Malirat V, Falczuk AJ. Evolving perception on the benefits of vaccination as a foot and mouth disease control policy: contributions of South America. Expert Rev Vaccines. 2005;4:903-13. https://doi.org/10.1586/14760584.4.6.903
  14. Knowles NJ, He J, Shang Y, Wadsworth J, Valdazo-Gonzalez B, Onosato H, et al. Southeast Asian foot-and-mouth disease viruses in Eastern Asia. Emerg Infect Dis. 2012;18:499-501. https://doi.org/10.3201/eid1803.110908
  15. Jamal SM, Ahmed S, Hussain M, Ali Q. Status of foot-and-mouth disease in Pakistan. Arch Virol. 2010;155:1487-91. https://doi.org/10.1007/s00705-010-0732-y
  16. Abubakar M, Kanwal S, Saeed A. Persistence, emergence and distribution of foot and mouth disease virus (FMDV); global and pakistan perspectives. Pak J Life Soc Sci. 2012;10(2):84-90.
  17. FAO. WRLFMD Quarterly Report January-March 2011. Reference laboratory contract Reports. 2011. http://www.wrlfmd.org/ref_labs/ref_lab_reports/OIE-FAO%20FMD%20Ref%20Lab%20Report%20Jan-Mar%202011.pdf.
  18. Mason PW, Grubman MJ, Baxt B. Molecular basis of pathogenesis of FMDV. Virus Res. 2003;91:9-32. https://doi.org/10.1016/S0168-1702(02)00257-5
  19. Saeed A, Khan QM, Waheed U, Arshad M, Asif M, Farooq M. RT-PCR evaluation for identification and sequence analysis of foot-and-mouth disease serotype O from 2006 to 2007 in Punjab, Pakistan. Comp Immunol Microbiol Infect Dis. 2011;34:95-101. https://doi.org/10.1016/j.cimid.2009.10.004
  20. Waheed U, Saeed A, Mobeen A, Khan QM. The VP1 (Capsid Protein) Gene Based DNA Sequencing for Epidemiological Analysis of FMDV, Isolated From Buffaloes in Pakistan. Pakistan J Zool (supp ser). 2009;9:333-9.
  21. Abubakar M, Arshed MJ, Ali Q, Hussain M. Spatial trend of Foot and Mouth Disease virus (FMDV) serotypes in cattle and buffaloes, Pakistan. Virol Sin. 2012;27(5):320-3. https://doi.org/10.1007/s12250-012-3271-8
  22. Bronsvoort BM, Radford AD, Tanya VN, Nfon C, Kitching RP, Morgan KL. Molecular epidemiology of foot-and-mouth disease viruses in the Adamawa province of Cameroon. J Clin Microbiol. 2004;42:2186-96. https://doi.org/10.1128/JCM.42.5.2186-2196.2004
  23. Islam MA, Rahman MM, Adam KH, Marquardt O. Epidemiological implications of the molecular characterization of foot-and-mouth disease virus isolated between 1996 and 2000 in Bangladesh. Virus Genes. 2001;23:203-10. https://doi.org/10.1023/A:1011821027235
  24. Klein J, Hussain M, Ahmad M, Afzal M, Alexandersen S. Epidemiology of foot-and-mouth disease in Landhi Dairy Colony, Pakistan, the world largest Buffalo colony. Virol J. 2008;5:53. https://doi.org/10.1186/1743-422X-5-53
  25. Carrillo C, Tulman ER, Delhon G, Lu Z, Carreno A, Vagnozzi A, et al. Comparative genomics of foot-and-mouth disease virus. J Virol. 2005;79:6487-504. https://doi.org/10.1128/JVI.79.10.6487-6504.2005
  26. Jackson AL, O'Neill H, Maree F, Blignaut B, Carrillo C, Rodriguez L, et al. Mosaic structure of foot-and-mouth disease virus genomes. J Gen Virol. 2007;88:487-92. https://doi.org/10.1099/vir.0.82555-0
  27. Aidaros HA. Regional status and approaches to control and eradication of foot and mouth disease in the Middle East and North Africa. Rev Sci Tech. 2002;21:451-8. http://dx.doi.org/10.14737/journal.rjvp/2014/2.2.28.29. https://doi.org/10.14737/journal.rjvp/2014/2.2.28.29
  28. Bastos AD, Haydon DT, Sangare O, Boshoff CI, Edrich JL, Thomson GR. The implications of virus diversity within the SAT 2 serotype for control of foot-and-mouth disease in sub-Saharan Africa. J Gen Virol. 2003;84:1595-606. https://doi.org/10.1099/vir.0.18859-0
  29. OIE. WAHID Interface OIE World Animal Health Information Database. 2008. https://www.oie.int/wahis/content.php?page=home&sslcheck=true.
  30. Kitching RP. Global epidemiology and prospects for control of foot-and-mouth disease. Curr Top Microbiol Immunol. 2005;288:133-48.
  31. Taboga O, Tami C, Carrillo E, Nunez JI, Rodriguez A, Saiz JC, et al. A large-scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants. J Virol. 1997;71:2606-14.
  32. Fry EE, Lea SM, Jackson T, Newman JW, Ellard FM, Blakemore WE, et al. The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex. EMBO J. 1999;18:543-54. https://doi.org/10.1093/emboj/18.3.543
  33. Alexandersen S, Zhang Z, Donaldson AI. Aspects of the persistence of foot-and-mouth disease virus in animals-the carrier problem. Microbes Infect. 2002;4:1099-110. https://doi.org/10.1016/S1286-4579(02)01634-9
  34. Doel TR. FMD vaccines. Virus Res. 2003;91:81-99. https://doi.org/10.1016/S0168-1702(02)00261-7
  35. Pan L, Zhang Y, Wang Y, Wang B, Wang W, Fang Y, et al. Foliar extracts from transgenic tomato plants expressing the structural polyprotein, p 1-2A, and protease, 3C, from foot-and-mouth disease virus elicit a protective response in guinea pigs. Vet Immunol Immunopathol. 2008;121:83-90. https://doi.org/10.1016/j.vetimm.2007.08.010
  36. Sobrino F, Saiz M, Jimenez-Clavero MA, Nunez JI, Rosas MF, Baranowski E, et al. Foot-and-mouth disease virus: a long known virus, but a current threat. Vet Res. 2001;32:1-30. https://doi.org/10.1051/vetres:2001106
  37. McKenna TS, Lubroth J, Rieder E, Baxt B, Mason PW. Receptor binding site-deleted foot-and-mouth disease (FMD) virus protects cattle from FMD. J Virol. 1995;69:5787-90.
  38. Selim A, Abouzeid N, Agaour A, Sobhy N. Comparative study for immune efficacy of two different adjuvants bivalent FMD vaccines in sheep. J Am Sci. 2010;6:1292-8.
  39. Deghaidy W, Daoud A, El-Molla A. Immune response of sheep to foot and mouth disease vaccines containing different adjuvants. Small Rumin Res. 2002;45:185-92. https://doi.org/10.1016/S0921-4488(02)00099-8
  40. Hunter P. Vaccination as a means of control of foot-and-mouth disease in sub-saharan Africa. Vaccine. 1998;16:261-4. https://doi.org/10.1016/S0264-410X(97)00170-9
  41. Iyer AV, Ghosh S, Singh SN, Deshmukh RA. Evaluation of three 'ready to formulate' oil adjuvants for foot-and-mouth disease vaccine production. Vaccine. 2000;19:1097-105. https://doi.org/10.1016/S0264-410X(00)00337-6
  42. Lombard M, Pastoret PP, Moulin AM. A brief history of vaccines and vaccination. Rev Sci Tech. 2007;26:29-48. https://doi.org/10.20506/rst.26.1.1724
  43. Abubakar M, Jamil A, Ali Q. An evaluation of foot-and-mouth disease outbreak in relation to vaccination in a herd of cattle and buffaloes. Res J Vet Pract. 2014;2(2):28-9. https://doi.org/10.14737/journal.rjvp/2014/2.2.28.29
  44. Batista A, Quattrocchi V, Olivera V, Langellotti C, Pappalardo JS, Di Giacomo S, et al. Adjuvant effect of Cliptox on the protective immune response induced by an inactivated vaccine against foot and mouth disease virus in mice. Vaccine. 2010;28:6361-6. https://doi.org/10.1016/j.vaccine.2010.06.098
  45. Rieder E, Baxt B, Lubroth J, Mason PW. Vaccines prepared from chimeras of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies and protective immunity to multiple serotypes of FMDV. J Virol. 1994;68:7092-8.
  46. Mason PW, Piccone ME, McKenna TS, Chinsangaram J, Grubman MJ. Evaluation of a live-attenuated foot-and-mouth disease virus as a vaccine candidate. Virology. 1997;227:96-102. https://doi.org/10.1006/viro.1996.8309
  47. Pfaff E, Mussgay M, Bohm HO, Schulz GE, Schaller H. Antibodies against a preselected peptide recognize and neutralize foot and mouth disease virus. EMBO J. 1982;1:869-74.
  48. Li Z, Yin X, Yi Y, Li X, Li B, Lan X, et al. FMD subunit vaccine produced using a silkworm-baculovirus expression system: protective efficacy against two type Asia1 isolates in cattle. Vet Microbiol. 2011;149:99-103. https://doi.org/10.1016/j.vetmic.2010.10.022
  49. Bittle JL, Houghten RA, Alexander H, Shinnick TM, Sutcliffe JG, Lerner RA, et al. Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature. 1982;298:30-3. https://doi.org/10.1038/298030a0
  50. Collen T, Dimarchi R, Doel TR. A T cell epitope in VP1 of foot-and-mouth disease virus is immunodominant for vaccinated cattle. J Immunol. 1991;146:749-55.
  51. Domingo E, Mateu MG, Matnez MA, Dopazo J, Moya A, Sobrino F. Genetic variability and antigenic diversity of foot-and-mouth disease virus. Appl Virol Res. 1990;2:233-66.
  52. Frimann TH, Barfoed AM, Aasted B, Kamstrup S. Vaccination of mice with plasmids expressing processed capsid protein of foot-and-mouth disease virus-importance of dominant and subdominant epitopes for antigenicity and protection. Vaccine. 2007;25:6191-200. https://doi.org/10.1016/j.vaccine.2007.06.002
  53. Cubillos C, de la Torre BG, Jakab A, Clementi G, Borras E, Barcena J, et al. Enhanced mucosal immunoglobulin A response and solid protection against foot-and-mouth disease virus challenge induced by a novel dendrimeric peptide. J Virol. 2008;82:7223-30. https://doi.org/10.1128/JVI.00401-08
  54. Zhang L, Zhang J, Chen HT, Zhou JH, Ma LN, Ding YZ, et al. Research in advance for FMD novel vaccines. Virol J. 2011;8:268. https://doi.org/10.1186/1743-422X-8-268
  55. Bae JY, Moon SH, Choi JA, Park JS, Hahn BS, Kim KY, et al. Recombinant DNA and protein vaccines for foot-and-mouth disease induce humoral and cellular immune responses in mice. Immune Netw. 2009;9:265-73. https://doi.org/10.4110/in.2009.9.6.265
  56. McCullough KC, De Simone F, Brocchi E, Capucci L, Crowther JR, Kihm U. Protective immune response against foot-and-mouth disease. J Virol. 1992;66:1835-40.
  57. Nain V, Verma A, Kumar N, Sharma P, Ramesh B, Kumar PA. Cloning of an ovule specific promoter from Arabidopsis thaliana and expression of beta-glucuronidase. Indian J Exp Biol. 2008;46:207-11.
  58. Saiz JC, Cairo J, Medina M, Zuidema D, Abrams C, Belsham GJ, et al. Unprocessed foot-and-mouth disease virus capsid precursor displays discontinuous epitopes involved in viral neutralization. J Virol. 1994;68:4557-64.
  59. Andrianova EP, Krementsugskaia SR, Lugovskaia NN, Mayorova TK, Borisov VV, Eldarov MA, et al. Foot and mouth disease virus polyepitope protein produced in bacteria and plants induces protective immunity in guinea pigs. Biochemistry (Mosc). 2011;76:339-46. https://doi.org/10.1134/S0006297911030072
  60. Grubman MJ, Baxt B. Foot-and-mouth disease. Clin Microbiol Rev. 2004;17:465-93. https://doi.org/10.1128/CMR.17.2.465-493.2004
  61. Grubman MJ. Development of novel strategies to control foot-and-mouth disease: marker vaccines and antivirals. Biologicals. 2005;33:227-34. https://doi.org/10.1016/j.biologicals.2005.08.009
  62. Grubman MJ, Moraes MP, Schutta C, Barrera J, Neilan J, Ettyreddy D, et al. Adenovirus serotype 5-vectored foot-and-mouth disease subunit vaccines: the first decade. Futur Virol. 2009;5:51-64.
  63. Pacheco JM, Brum MC, Moraes MP, Golde WT, Grubman MJ. Rapid protection of cattle from direct challenge with foot-and-mouth disease virus (FMDV) by a single inoculation with an adenovirus-vectored FMDV subunit vaccine. Virology. 2005;337:205-9. https://doi.org/10.1016/j.virol.2005.04.014
  64. Li X, Liu R, Tang H, Jin M, Chen H, Qian P. Induction of protective immunity in swine by immunization with live attenuated recombinant pseudorabies virus expressing the capsid precursor encoding regions of foot-and-mouth disease virus. Vaccine. 2008;26:2714-22. https://doi.org/10.1016/j.vaccine.2008.03.020
  65. Mason HS, Ball JM, Shi JJ, Jiang X, Estes MK, Arntzen CJ. Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice. Proc Natl Acad Sci U S A. 1996;93:5335-40. https://doi.org/10.1073/pnas.93.11.5335
  66. Wigdorovitz A, Mozgovoj M, Santos MJ, Parreno V, Gomez C, Perez-Filgueira DM, et al. Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants. J Gen Virol. 2004;85:1825-32. https://doi.org/10.1099/vir.0.19659-0
  67. Zulfiqar M. Support for Emergency Prevention and Control of Main Trans-boundary Animal Diseases in Pakistan, Rinderpest, FMD, PPR. 2003.
  68. Carrillo C, Wigdorovitz A, Oliveros JC, Zamorano PI, Sadir AM, Gomez N, et al. Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants. J Virol. 1998;72:1688-90.
  69. Wigdorovitz A, Carrillo C, Dus Santos MJ, Trono K, Peralta A, Gomez MC, et al. Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1. Virology. 1999;255:347-53. https://doi.org/10.1006/viro.1998.9590
  70. Carrillo C, Wigdorovitz A, Trono K, Dus Santos MJ, Castanon S, Sadir AM, et al. Induction of a virus-specific antibody response to foot and mouth disease virus using the structural protein VP1 expressed in transgenic potato plants. Viral Immunol. 2001;14:49-57. https://doi.org/10.1089/08828240151061383
  71. Haq TA, Mason HS, Clements JD, Arntzen CJ. Oral immunization with a recombinant bacterial antigen produced in transgenic plant. Science. 1995;268:714-6. https://doi.org/10.1126/science.7732379
  72. Thanavala Y, Yang YF, Lyons P, Mason HS, Arntzen C. Immunogenicity of transgenic plant-derived hepatitis B surface antigen. Proc Natl Acad Sci U S A. 1995;92:3358-61. https://doi.org/10.1073/pnas.92.8.3358
  73. Sun M, Qian K, Su N, Chang H, Liu J, Shen G. Foot-and-mouth disease virus VP1 protein fused with cholera toxin B subunit expressed in Chlamydomonas reinhardtii chloroplast. Biotechnol Lett. 2003;25:1087-92. https://doi.org/10.1023/A:1024140114505
  74. He DM, Qian KX, Shen GF, Li YN, Zhang ZF, Su ZL, et al. Stable expression of foot-and-mouth disease virus protein VP1 fused with cholera toxin B subunit in the potato (Solanum tuberosum). Colloids Surf B Biointerfaces. 2007;55:159-63. https://doi.org/10.1016/j.colsurfb.2006.11.043
  75. Joensuu JJ, Brown KD, Conley AJ, Clavijo A, Menassa R, Brandle JE. Expression and purification of an anti-Foot-and-mouth disease virus single chain variable antibody fragment in tobacco plants. Transgenic Res. 2009;18:685-96. https://doi.org/10.1007/s11248-009-9257-0
  76. Hood E, Witcher D, Maddock S, Meyer T, Baszczynski C, Bailey M, et al. Commercial production of avidin from transgenic maize: characterization of transformant, production, processing, extraction and purification. Mol Breed. 1997;3:291-306. https://doi.org/10.1023/A:1009676322162
  77. Streatfield SJ, Jilka JM, Hood EE, Turner DD, Bailey MR, Mayor JM, et al. Plant-based vaccines: unique advantages. Vaccine. 2001;19:2742-8. https://doi.org/10.1016/S0264-410X(00)00512-0