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Effect of Route of Preoperative Biopsy on Endoscopic Submucosal Dissection for Patients with Early Gastric Cancer

  • Jiang, Hui ;
  • Tu, Hui-Ming ;
  • Qiao, Qiao ;
  • Xu, Ke-Bin ;
  • Li, Jie ;
  • Qi, Xiao-Wei ;
  • Ge, Xiao-Song
  • Published : 2014.11.06

Abstract

Objective: To observe and compare the effects of multi-patch biopsy under conventional white light imaging endoscopy (C-WLI) and precise targeted biopsy under magnifying narrow-band imaging endoscopy (M-NBI) on the endoscopic submucosal dissection (ESD) of early gastric cancers and intraepithelial neoplasias. Methods: According to the way of selecting biopsy specimens, patients were divided into C-WLI and M-NBI groups, 20 cases. The ESD operations of the 2 groups were compared quantitively. Results: The mean frequency of biopsy in M-NBI group was ($1.00{\pm}0.00$), obviously lower than in the C-WLI group ($4.78{\pm}1.02$) (P<0.01).The average total number of selected biopsy specimens was also fewer ($1.45{\pm}0.12$ and $7.82{\pm}2.22$, respectively, P<0.01). There was no significant difference in the time of determining excision extension, marking time and the time of specimen excision of 2 groups during the ESD (P>0.05), whereas submucosal injection time, mucosal dissection time, stopping bleeding time, wound processing time in the M-NBI group were significantly shorter than in the C-WLI group (P<0.01). Conclusion: Precise targeted biopsy under M-NBI can obviously shorten the time of ESD operation, with small quantity of tissues but high pathological positive rate.

Keywords

Early gastric cancer;endoscopy;biopsy;magnifying narrow-band imaging;white light imaging

References

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  1. Comparison of the diagnostic efficacy of white light endoscopy and magnifying endoscopy with narrow band imaging for early gastric cancer: a meta-analysis vol.19, pp.2, 2016, https://doi.org/10.1007/s10120-015-0500-5
  2. Role of targeted biopsy under magnifying endoscopy with narrow band imaging may be not necessary vol.29, pp.4, 2017, https://doi.org/10.1097/MEG.0000000000000802
  3. Low Discrepancy Between Tissue Biopsy Plus Magnifying Endoscopy With Narrow-Band Imaging and Endoscopic Resection in the Diagnosis of Gastric Epithelial Neoplasia (STROBE) vol.94, pp.27, 2015, https://doi.org/10.1097/MD.0000000000001092