- Volume 15 Issue 20
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Pharmacoeconomics Evaluation of Morphine, MS Contin and Oxycodone in the Treatment of Cancer Pain
- Zhang, Wen-Zhou (Department of Pharmacy, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University) ;
- Yu, Wei-Jiang (Department of Pharmacy, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University) ;
- Zhao, Xiu-Li (Department of Pharmacy, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University) ;
- He, Bao-Xia (Department of Pharmacy, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University)
- Published : 2014.11.06
Objective: To analyze cost-effectiveness of morphine, MS contin and oxycodone in the treatment of cancer pain, providing guidance for rational drug use in the clinic. Methods: Confirmed by histology, a total of 171 patients with various cancers who required analgesic treatment were selected and divided into 3 groups, 57 cases for each group, given morphine, MS contin and oxycodone, respectively. If there appeared a poor short-term effect or aggravated sudden pain during the treatment, a short-acting morphine injection was given and adverse reactions were processed by symptomatic treatment. The pain relief rate and adverse reactions of groups were observed and pharmacoeconomics evaluation was undertaken. Results: The pain relief rates with morphine, MS contin and oxycodone were 89.5%(51/57), 91.2%(52/57) and 93.0%(53/57), respectively, with no difference samong groups (
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