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Epidemiology of Female Reproductive Cancers in Iran: Results of the Gholestan Population-Based Cancer Registry

  • Taheri, NegarSadat ;
  • Fazel, Abdolreza ;
  • Mahmoodzadeh, Habibollah ;
  • Omranpour, Ramesh ;
  • Roshandel, Gholamreza ;
  • Gharahjeh, Saeedeh ;
  • Sedaghat, Seyed Mehdi ;
  • Poorabbasi, Mohammad ;
  • Moghaddami, Abbas ;
  • Semnani, Shahryar
  • Published : 2014.11.06

Abstract

Background: Malignancies of the female reproductive tract are estimated to be the third most common group of cancers in women. Objectives: We here aimed to present their epidemiological features in Golestan province located in Northeast of Iran. Materials and Methods: Data on primary female reproductive cancers diagnosed between 2004-2010 were obtained from Golestan Population-based Cancer Registry (GPCR). CanReg-4 and SPSS software were used for data entry and analysis. Age standardized incidence rates (ASR) (per 100,000 person-years) were calculated using the world standard population. Poisson regression analysis was used to compare incidence rates. P-values of less than 0.05 were considered as significant. Results: A total of 6,064 cancer cases were registered in Golestan females in the GPCR during 2004-2010, of which 652 cases (11%) were female reproductive cancers. Cancers of the ovary (ASR=6.03) and cervix (ASR=4.97) were the most common. We found significant higher rates in females living in cities than in villages. Our results showed a rapid increase in age specific incidence rates of female reproductive cancers at the age of 30 years. Conclusions: We found significant higher rates of female reproductive cancers among residents of cities than villages. Differences in the prevalence of risk factors including reproductive behavior between the two populations may partly explain such diversity. Our results also showed a rapid increase in incidence rates of these cancers in young age females. Further studies are warranted to determine risk factors of female reproductive cancers in our population.

Keywords

Female reproductive cancers;epidemiology;Golestan;Iran

References

  1. Arab M, Noghabaei G, Kazemi SN (2014). Comparison of crude and age-specific incidence rates of breast, ovary, endometrium and cervix cancers in Iran, 2005. Asian Pac J Cancer Prev, 15, 2461-4. https://doi.org/10.7314/APJCP.2014.15.6.2461
  2. Ferlay J, Soerjomataram I, Ervik M, et al 2013. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11, Lyon, France, International Agency for Research on Cancer.
  3. Forman D, Bray F, Brewster DH, et al 2013. Cancer Incidence in Five Continents, Vol. X, Lyon, International Agency for Research on Cancer.
  4. Fritz A, Percy C, Jack A, et al 2000. International Classification of Diseases for Oncology, Geneva, World Health Oganization.
  5. Goya M 2007. Iranian Annual Cancer Registration Report 2005/2006, Tehran, Center for Disease Control and Prevention, Iranian Ministry of Health and Medical Education.
  6. Binesh F, Akhavan A, Behniafard N, et al (2014). Endometrial adenocarcinoma: clinicopathologic and survival characteristics in Yazd, Iran. Asian Pac J Cancer Prev, 15, 2797-801. https://doi.org/10.7314/APJCP.2014.15.6.2797
  7. Jemal A, Bray F, Center MM, et al (2011). Global cancer statistics. CA Cancer J Clin, 61, 69-90. https://doi.org/10.3322/caac.20107
  8. Lowe KA, Chia VM, Taylor A, et al (2013). An international assessment of ovarian cancer incidence and mortality. Gynecol Oncol, 130, 107-14. https://doi.org/10.1016/j.ygyno.2013.03.026
  9. Mathers C, Fat DM, Boerma JT 2008. The global burden of disease: 2004 update, Switzerland, World Health Organization.
  10. Naghavi M, Abolhassani F, Pourmalek F, et al (2009). The burden of disease and injury in Iran 2003. Popul Health Metr, 7, 9. https://doi.org/10.1186/1478-7954-7-9
  11. National Cancer Intelligence Network 2008. Cancer Incidence and Mortality by Cancer Network, UK, 2005, London, National Cancer Intelligence Network.
  12. Parkin DM, Bray F, Ferlay J, et al (2001). Estimating the world cancer burden: Globocan 2000. Int J Cancer, 94, 153-6. https://doi.org/10.1002/ijc.1440
  13. Rohani-Rasaf M, Moradi-Lakeh M, Ramezani R, et al (2012). Measuring socioeconomic disparities in cancer incidence in Tehran, 2008. Asian Pac J Cancer Prev, 13, 2955-60. https://doi.org/10.7314/APJCP.2012.13.6.2955
  14. Rohani-Rasaf M, Abdollahi M, Jazayeri S, et al (2013). Correlation of cancer incidence with diet, smoking and socio- economic position across 22 districts of Tehran in 2008. Asian Pac J Cancer Prev, 14, 1669-76. https://doi.org/10.7314/APJCP.2013.14.3.1669
  15. Roshandel G, Sadjadi A, Aarabi M, et al (2012). Cancer incidence in Golestan Province: report of an ongoing population-based cancer registry in Iran between 2004 and 2008. Arch Iran Med, 15, 196-200.
  16. Sasco AJ (2001). Epidemiology of uterine cancers. Rev Prat, 51, 1408-12.
  17. Taheri NS, Bakhshandehnosrat S, Tabiei MN, et al (2012). Epidemiological pattern of breast cancer in Iranian women: is there an ethnic disparity? Asian Pac J Cancer Prev, 13, 4517-20. https://doi.org/10.7314/APJCP.2012.13.9.4517
  18. Talaiezadeh A, Tabesh H, Sattari A, et al (2013). Cancer incidence in Southwest of Iran: first report from Khuzestan population-based cancer registry, 2002-2009. Asian Pac J Cancer Prev, 14, 7517-22. https://doi.org/10.7314/APJCP.2013.14.12.7517

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