- Volume 15 Issue 19
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Role of the HPV DNA Test in Follow-up of Treated Cervical Intraepithelial Neoplasia in Bangladesh
- Nessa, Ashrafun (Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University) ;
- Rashid, Mohammad Harun Ur (Planning and Research Unit, Directorate General of Health Services) ;
- Jahan, Munira (Department of Virology, Bangabandhu Sheikh Mujib Medical University) ;
- Ferdous, Noor-E (Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University) ;
- Nahar, Pervin Akhter Shamsun (Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University) ;
- Chowdhury, Afroza (Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University)
- Published : 2014.10.23
Background: Cervical cancer is a major public health problem in Bangladesh. Persistence of high risk human papillomavirus (HRHPV) influences the progression of the disease, with an important role in followup for cervical intraepithelial neoplasia (CIN). Objective: To establish application of high risk HPV DNA test in the follow-up of women after treatment of CIN. Materials and Methods: This cross-sectional and hospital based study was carried out among 145 CIN treated women during the previous six months to three years at the colposcopy clinic of Bangabandhu Sheikh Mujib Medical University, Dhaka, between January 2011 and June 2012. Pap smear and HPV samples were collected and colposcopy was performed to find out the persistence of the disease. Cervical samples obtained were tested for HPV DNA using the Hybrid Capture II (HC-II) test. A cervical biopsy was collected whenever necessary. The results were compared to assess the efficacy of different methods during follow up such as Pap smear, HPV test and colposcopy. Results: Mean age of the recruited women (n=145) was 33.6 (
HPV DNA test;follow-up;treated CIN;Bangladesh
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