DOI QR코드

DOI QR Code

Distribution of Yeast Isolated from Clinical Specimens at a University Hospital in last Five Years

최근 5년간 단일 대학병원의 임상검체에서 분리된 효모균의 분포

  • Seo, Choong-Won (Dept. of Biomedical Laboratory Science, Seonam University) ;
  • Yu, Young-Bin (Dept. of Biomedical Laboratory Science, Konyang University) ;
  • Shin, Kyeong Seob (Dept. of Laboratory Medicine, Chungbuk National University College of Medicine) ;
  • Kim, Young-Kwon (Dept. of Biomedical Laboratory Science, Konyang University)
  • 서충원 (서남대학교 임상병리학과) ;
  • 유영빈 (건양대학교 임상병리학과) ;
  • 신경섭 (충북의과대학 진단검사의학과) ;
  • 김영권 (건양대학교 임상병리학과)
  • Received : 2014.06.18
  • Accepted : 2014.09.20
  • Published : 2014.09.28

Abstract

Pathogenic fungal infections are predominantly occurred in patients with severe immune or metabolic defects. In the present study, we aimed to investigate the last five years (2007~2011) 190,250 cases clinical specimens of yeast 3,487 results that had shown positive culture and to look at the significance of regional difference and identify relationship between provide the characteristics about association between clinical isolates and gender, age, and type of specimens. The yearly strain-specific isolation frequency of yeast separated was 1,925(55.2%) for C. albicans the largest of them. All kinds of clinical specimen was 1,495(42.9%) in urine, 998(28.6%) in sputum. Strain-specific gender differences in C. albicans for males was 1,177(57.8%) of the total of 2,037 and 748(51.6%) of 1,450 and as for age, those between 70 and 79 were the largest with 639(55.1%) of the 1,925 strain. In this study, well presented the general characteristics of pathogenic yeast seen in diverse specimens. This limitation has been implemented in a single area, Future research is expected to examine more on nationwide distribution chart, dynamic characteristics and future antibiotic sensitivity.

Keywords

distribution;C. albicans;Vitek 2;Yeast;specimen

Acknowledgement

Supported by : 건양대학교

References

  1. J. Akansa, J. Shubham, and R. Swati, Emerging fungal infections among children: A review on its clinical manifestations, diagnosis, and prevention. Vol. 2, No. 4, pp. 314-320, 2010. https://doi.org/10.4103/0975-7406.72131
  2. G. Y. Ahn, S. J. Jang, S. H. Lee, O. Y. Jeong, B. P. Chaulagain, and D. S. Moon, Trends of the species and antimicrobial susceptibility of microorganisms isolated from blood cultures of patients. Korea Journal of Clinical Microbiology, Vol. 9, No. 1, pp. 42-50, 2006.
  3. J. S. Lee, J. H. Shin, and K. Lee, Species distribution and susceptibility to azole antifungals of Candida bloodstream isolates from eight university hospitals in Korea. Yonsei Medical Journal, Vol. 48, No. 5, pp. 779-786, 2007. https://doi.org/10.3349/ymj.2007.48.5.779
  4. S. H. Shin, Y. B. Park, and D. S. Shin, Isolation Frequency of Candida species from Clinical Specimens. Korea Journal of Mycology, Vol. 38, No. 2, pp. 146-151, 2010. https://doi.org/10.4489/KJM.2010.38.2.146
  5. E. M. Koh, S. G. Lee, C. G. Kim, M. S. Kim, D. E. Yong, and K. W. Lee, Microorganisms Isolated from Blood Cultures and Their Antimicrobial Susceptibility Patterns At a University Hospital During 1994-2003, Korean Journal of Laboratory Medicine, Vol. 27, No. 4, pp. 265-275, 2007. https://doi.org/10.3343/kjlm.2007.27.4.265
  6. M. B. Edmond, S. E. Wallace, D. K. McClish, M. A. Pfaller, R. N. Jones, R. P. Wenzel, Nosocomial bloodstream infections in United States hospital a three year analysis. Clinical Infectious Disease, Vol. 29, No. 2, pp. 239-244, 1999. https://doi.org/10.1086/520192
  7. V. Kremery, and A. J. Barnes, Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance. The Journal of Hospital Infection, Vol. 50, No. 4, pp. 243-260, 2002. https://doi.org/10.1053/jhin.2001.1151
  8. W. E. Trick, S. K. Fridkin, J. R. Edwards, R. A. Hajjeh, and R. P. Gaynes, National Nosocomial Infections Surveillance System Hospitals. Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999. Clinical Infectious Disease, Vol. 35, pp. 627-630, 2002. https://doi.org/10.1086/342300
  9. A. M. Tortorano, E. Biraghi, and A. Astolfi, European Confederation of Medical Mycology (ECMM) prospective survey of candidaemia: report from one Italian region. Journal of Hospital Infection, Vol. 51, No. 4, pp. 297-304, 2002. https://doi.org/10.1053/jhin.2002.1261
  10. A. M. Tortorano, L. Caspani, A. L. Rigoni, E. Biraghi, A. Sicignano, and M. A. Viviani, Candidosis in the intensive care unit: a 20-year survey. Journal of Hospital Infection, Vol. 57, No. 1, pp. 8-13, 2004. https://doi.org/10.1016/j.jhin.2004.01.017
  11. J. Garbino, L. Kolarova, P. Rohner, D. Lew, P. Pichna, and D. Pittet, Secular trends of candidemia over 12 years in adult patients at a tertiary care hospital. Medicine(Baltimore), Vol. 81, No. 6, pp. 425-433, 2002.
  12. C. A. Mullen, H. Abdel-Baki, H. Samir, J. J. Tarrand, and K. V. Rolston, Non-albicans Candida is the most common cause of candidemia in pediatric cancer patients. Supportive Care in Cancer, Vol. 11, No. 5, pp. 321-325, 2003.
  13. A. Safdar, D. S. Perlin, and D. Armstrong, Hematogenous infections due to Candida parapsilosis: changing trends in fungemic patients at a comprehensive cancer center during the last four decades. Diagnosis Microbiology and Infectious Disease, Vol. 44, No. 1, pp. 11-16, 2002. https://doi.org/10.1016/S0732-8893(02)00423-6
  14. E. J. Won, J. H. Shin, W. K. Lee, S. H. Koo, S. Y. Kim, and Y. J. Park, Distribution of Yeast and Mold Species Isolated from Clinical Specimens at 12 Hospitals in Korea during 2011. Annals of Clinical Microbiology and Antimicrobials, Vol. 16, No. 2, pp. 92-100, 2013. https://doi.org/10.5145/ACM.2013.16.2.92
  15. M. S. Saag, R. J. Graybill,R. A. Larsen, P. G. Pappas, J. R. Perfect, and W. G. Powderly, Practice guidelines for the management of cryptococcal disease. Clinical Infectious Disease, Vol. 30, No. 4, pp. 710-718, 2000. https://doi.org/10.1086/313757
  16. V. Silva, G. Zepeda, and D. Alvareda, Nosocomial urinary tract infection due to Trichosporon asahii. First two cases in Chile. Revista Iberoamericana de Micologia, Vol. 20, No. 1, pp. 21-23, 2003.
  17. H. J. Moon, J. B. Lee, S. J. Kim, S. C. Lee, and Y. H. Won, Clinical and Mycological Studies on Dermatomycosis (1991-2000). Korea Journal of Medical Mycology, Vol. 7, No. 2, pp.78-85, 2002.