- Volume 15 Issue 16
DOI QR Code
Differencies in Risk Factors for Cervical Dysplasia with the Applied Diagnostic Method in Serbia
- Antic, Ljiljana Gojko (Department for Medical Nurses-Midwives, College of Health Studies in Cuprija) ;
- Vukovic, Dejana Srboljub (Institute for Social Medicine, Medical Faculty University of Belgrade) ;
- Vasiljevic, Mladenko Drago (University Clinic of Gynaecology and Obstetrics Narodni Front, Medical Faculty University of Belgrade) ;
- Antic, Dragan Zivojin (Department for Medical Nurses-Midwives, College of Health Studies in Cuprija) ;
- Aleksopulos, Hristos Georgios (Department for Medical Nurses-Midwives, College of Health Studies in Cuprija)
- Published : 2014.08.30
Background: In the etiology of cervical cancer not only HPV infection is important, but also other factors such as demographic influences andsexual and reproductive health attitudes, as well as others related to preventive measure usage (or non usage). The aim of this study was to examine factors associated with cervical dysplasia in asymptomatic women who were examined by routine cytology and cervical biopsy for early detection of cervical cancer. Materials and Methods: Socio-demographic and other characteristics were obtained from medical files of 85 examinees with pathologic cytologic findings (Pap test) and histopathologic (HP) findings after biopsy. Results: ccording to the Pap test result, a greater probability for development of cervical dysplasia was noted with examinees having a larger number of sexual partners (OR= 5.01, 95% CI 1.04-24.10), and those who are afraid of the Pap finding. Risk factors for development of cervical dysplasia according to the bioptic finding were early beginning with sexual activities, presence of any STD in personal medical history and fear of the Pap test finding. Conclusions: The only risk factor found to be important for both methods was fear of the Pap testing finding.
Cervical dysplasia;risk factors;cytology;Pap smear;histopathology;Serbia
- Antic LJ, Dikanovic B, Vukovic D (2013). Family planning practices among women in urban and rural areas in Serbia. Srpski arhiv za celokupno lekarstvo, 11-12, 794-9.
- Apgar BS, Brotzman G (2004). Management of cervical cytologic abnormalities. Am Fam Physician, 10, 1905-16.
- Baer H, Allen S, Braun L (2000). Knowledge of human papillomavirus infection among young adult men and women: implications for health education and research. J Community Health, 25, 67-78. https://doi.org/10.1023/A:1005192902137
- Billstrom E, Sundstrom-Poromaa I, Stalberg K, Asplund A, Hellberg D (2013). Socioeconomic characteristics, housing conditions and criminal offences among women with cervical neoplasia. Acta Obstet Gynecol Scand, 8, 888-94.
- Bosch FX, Lorincz A, Munoz N, Meijer CJ, Shah KV (2002).The causal relation between human papillomavirus and cervical cancer. J Clin Pathol, 55, 244-65. https://doi.org/10.1136/jcp.55.4.244
- Boicea A, Patrascu A, Surlin V, Iliescu D, Schenker M, Chiutu L (2012). Correlations between colposcopy and histologic results from colposcopically directed biopsy in cervical precancerous lesions. Rom J Morphol Embryol, 3, 735-41.
- Chan PK, Chang AR, Cheung JL, et al (2002).Determinants of cervical human papillomavirus infection: differences between high- and low-oncogenic risk types. J Infect Dis, 1, 28-35.
- Chankapa YD, Pal R, Tsering D (2011). Correlates of cervical cancer screening among underserved women. Indian J Cancer, 1, 40-6.
- Castellsague X, Munoz N. (2000).Chapter 3: Cofactors in human papillomavirus carcinogenesis--role of parity, oral contraceptives, and tobacco smoking. J Natl Cancer Inst Monogr, 31, 20-8.
- Cuzick J, Arbyn M, Sankaranarayanan R, et al (2008).Overview of human papillomavirus-based and other novel options for cervicalcancer screening in developed and developing countries.Vaccine, 10, 29-41.
- Clement KM, Mansour D (2013).Invasive cancer of the cervix: does the UK National Health Service screening programme fail due to patients' non-attendance? Eur J Gynaecol Oncol, 1, 28-30.
- Duval B, Gilca V, Boulianne N, et al (2009). Cervical cancer prevention by vaccination: nurses' knowledge, attitudes and intentions. J Adv Nurs, 65, 499-508. https://doi.org/10.1111/j.1365-2648.2008.04900.x
- Dugandzija T, Mikov MM, Rajcevic S, et al (2012). Information sources for Serbian women on cervical carcinoma risk factors. Asian Pac J Cancer Prev, 13, 2931-34. https://doi.org/10.7314/APJCP.2012.13.6.2931
- Datta SD, Saraiya M (2011). Cervical cancer screening among women who attend sexually transmitted diseases (STD) clinics: background paper for 2010 STD Treatment Guidelines. Clin Infect Dis, 3, 153-9.
- Deacon JM, Evans CD, Yule R, et al (2000). Sexual behaviour and smoking as determinants of cervical HPV infection and of CIN3 among those infected: a case-control study nested within the Manchester cohort. Br J Cancer, 83, 1565-72. https://doi.org/10.1054/bjoc.2000.1523
- Gottvall M, Larsson M, Hoglund AT, Tyden T (2009). High HPV vaccine acceptance despite low awareness among Swedish upper secondary school students. Eur J Contracept Reprod Health Care, 14, 399-405. https://doi.org/10.3109/13625180903229605
- Gadducci A, Barsotti C, Cosio S, Domenici L, Genazzani A (2011). Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: a review of the literature. Gynecol Endocrinol, 8, 597-604.
- Hoque ME, Ghuman S, Hal GV (2013). Human papillomavirus vaccination acceptability among female university students in South Africa. Asian Pac J Cancer Prev, 14, 4865-9. https://doi.org/10.7314/APJCP.2013.14.8.4865
- Indarti J, Aziz MF, Suryawati B, Fernando D (2013). Scoring system and management algorithm assessing the role of survivin expression in predicting progressivity of HPV infections in precancerous cervical lesions. Asian Pac J Cancer Prev, 3, 1643-7. https://doi.org/10.7314/APJCP.2013.14.3.1643
- Institute for Clinical Systems Improvement (ICSI) (2005). Cervical cancer screening.Bloomington (MN): Institute for Clinical Systems Improvement (ICSI), 38.
- International Collaboration of Epidemiological Studies of Cervical Cancer (2009). Cervical carcinoma and sexual behavior: collaborative reanalysis of individual data on 15,461 women with cervical carcinoma and 29,164 women without cervical carcinoma from 21 epidemiological studies . Cancer Epidemiol Biomarkers Prev, 18, 1060-9. https://doi.org/10.1158/1055-9965.EPI-08-1186
- Jiang Y, Hanley B, Brassard P, et al (2013). Human papillomavirus infection and the association with abnormal Pap findings in Yukon, Canada. J Low Genit Tract Dis, 3, 346-53.
- Kanno MB, Nguyen RH, Lee EM, Zenilman JM, Erbelding EJ (2005). The prevalence of abnormal cervical cytology in a sexually transmitted diseases clinic. Int J STD AIDS, 8, 549-52.
- Karimi-Zarchi M, Peighmbari F, Karimi N, Rohi M, Chiti Z (2013). A comparison of 3 ways of conventional pap smear, liquid-based cytology and colposcopy vs cervical biopsy for early diagnosis of premalignant lesions or cervical cancer in women with abnormal conventional Pap test. Int J Biomed Sci, 4, 205-10.
- Kjellberg L, Hallmans G, Ahren AM, et al (2000). Smoking, diet, pregnancy and oral contraceptive use as risk factors for cervical intra-epithelial neoplasia in relation to human papillomavirus infection. Br J Cancer, 7, 1332-38.
- Kent H, Heffernan ME, Silvers J, Moore E, Garland SM (2010). Role of the nurse immuniser in implementing and maintaining the National Human Papillomavirus 'Cervical Cancer' Vaccine rollout through a school-based program in Victoria. Sex Health, 7, 391-403. https://doi.org/10.1071/SH09148
- Labeit A, Peinemann F, Kedir A (2013).Cervical cancer screening service utilisation in UK. Sci Rep, 3, 2362.
- Matejic B, Kesic V, Markovic M, Topic L (2008). Communications about cervical cancer between women and gynecologists in Serbia. Int J Public Health, 53, 245-51. https://doi.org/10.1007/s00038-008-7102-5
- Ministry of Health Republic of Serbia (2006) National Health Survey for the population of Republic of Serbia (without data on Kosovo and Metohia), 446-530.
- Natphopsuk S, Settheetham-Ishida W, Sinawat S, Pientong C, Yuenyao P, Ishida T (2012). Risk factors for cervical cancer in northeastern Thailand: detailed analyses of sexual and smoking behavior. Asian Pac J Cancer Prev, 11, 5489-95. https://doi.org/10.7314/APJCP.2012.13.11.5489
- Poomtavorn Y, Himakhun W, Suwannarurk K, Thaweekul Y, Maireang K (2013). Cytohistologic discrepancy of highgrade squamous intraepithelial lesions in Papanicolaou smears. Asian Pac J Cancer Prev, 1, 599-602.
- Patil V, Wahab SN, Zodpey S, Vasudeo ND (2006). Development and validation of risk scoring system for prediction of cancer cervix. Indian J Public Health, 1, 38-42.
- Reiter P, Katz M, Ferketich A, Mack T, Ruffin M, Paskett E (2009). Measuring cervical cancer risk: development and validation of the CARE Risky Sexual Behavior Index. Cancer Causes Control, 20, 1865-71. https://doi.org/10.1007/s10552-009-9380-5
- Reich O (2005). Is early first intercourse a risk factor for cervical cancer?. Gynakol Geburtshilfliche Rundsch, 4, 251-6.
- Rong S, Chen W, Wu L, et al (2002). Analysis of risk factors for cervical cancer in Xiangyuan County, Shanxi Province. Zhonghua Yu Fang Yi Xue Za Zhi, 1, 41-3 (in Chinese).
- SuwaIa M, Gerstenkorn A, WesoIowska R (2012). Knowledge about tobacco smoking as a cervical cancer risk factor among economically active nurses from Lodz region. Przegl Lek, 10, 965-8.
- Smith JS, Green J, Berrington de Gonzalez A, et al (2003). Cervical cancer and use of hormonal contraceptives: a systematic review. Lancet, 5, 1159-67.
- Smith JS, Bosetti C, Munoz N, et al (2004). Chlamydia trachomatis and invasive cervical cancer: a pooled analysis of the IARC multicentric case-control study. Int J Cancer, 11, 431-9.
- Smith JS, Herrero R, Bosetti C, et al (2002). Herpes simplex virus-2 as a human papillomavirus cofactor in the etiology of invasive cervical cancer. J Natl Cancer Inst, 21, 1604-13.
- Thulaseedharan JV, Malila N, Hakama M, et al (2012). Socio demographic and reproductive risk factors for cervical cancer - a large prospective cohort study from rural India. Asian Pac J Cancer Prev, 13, 2991-5. https://doi.org/10.7314/APJCP.2012.13.6.2991
- Vivilaki V, Romanidou A, Theodorakis PN, Lionis C (2005). Are health education meetings effective in recruiting women in cervical screening programmes?An innovative and inexpensive intervention from the island of Crete. Rural Remote Health, 2, 376.
- Development of a Risk Index for Prediction of Abnormal Pap Test Results in Serbia vol.16, pp.8, 2015, https://doi.org/10.7314/APJCP.2015.16.8.3527