- Volume 15 Issue 17
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Patterns of Upper Aero-digestive Tract Cancers in Kamrup Urban District of Assam: A Retrospective Study
- Sharma, Jagannath Dev (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Kalita, Manoj (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Barman, Debanjana (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Sharma, Arpita (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Lahon, Ranjan (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Barbhuiya, Jamil Ahmed (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Deka, Barsha (Population Based Cancer Registry, National Cancer Registry Programme (ICMR)) ;
- Kataki, Amal Chandra (Dr. B. Borooah Cancer Institute)
- Published : 2014.09.15
Background: The incidence of upper aero-digestive tract (UADT) cancers, including C00-C14, C30-C32, C15 and C16, is increasing rapidly in Kamrup Urban District (KUD) of Assam, North East (NE) India. According to the NCRP (2013) report 37.6% of all cancers in both sexes are UADT cancers in the NE region, accounting for 53.3% in males and about 27.5% in females of the total cases. Materials and Methods: A retrospective study was conducted for patient information from the period of 2008-2011. Age-standardized or age-adjusted rates (ASR or AAR) (per 100,000 person-years) were calculated using the World Standard Population as proposed by Segi and modified by Doll et al. The registry population area at risk was estimated using the 1991 and 2001 census population by sex, as well as the growth rate during that interval using the difference distribution method. Results: There were 5,638 cases registered during the last four years of the study (2008-2011) accounting for 56.7% (3,198/5,638) of the total in males and 43.3% (2,440/5,638) in females. The male: female ratio was 1.31:1.00. The overall age adjusted rates (AAR) were 179.4 and 153.8 per 100 000 males and females respectively. Cancer of the oesophagus was most common in both sexes, with most appreciable gender variation for tongue and hypopharynx, presumably reflecting differential expsoure to risk factors.
- Anantharaman D, Chabrier AL, Gaborieau VR, et al (2014). Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: a replication study in india. Plos One, 9, 1-7.
- Doll R, Payne P, Waterhouse JAH, et al (1966). Cancer incidence in five continents. vol i. geneva: union internationale contre le cancer, Berlin, Springer.
- Jemal A, Bray F, Center MM, et al (2011). Global cancer statistics. Ca Cancer J Clin, 61, 69-90. https://doi.org/10.3322/caac.20107
- Krishnatreya M, Gogoi G, Sharma JD, Kataki AC (2014). Patterns of cancer in select ethnic groups from assam: a retrospective study. Int Res J. Social Sci, 3, 17-20.
- Kumar A, Chatopadhyay T, Raziuddin T, Ralhan R (2006). Discovery of deregulation of zinc homeostasis and its associated genes in esophageal squamous cell carcinoma using cDNA microarray. Int. J. Cancer, 120, 230-42.
- Malakar M, Devi KR, Phukan RK, et al (2014). p53 Codon 72 polymorphism interactions with dietary and tobacco related habits and risk of stomach cancer in Mizoram, India. Asian Pac J Cancer Prev, 15, 717-23. https://doi.org/10.7314/APJCP.2014.15.2.717
- Mishra A, Meherotra R (2014). Head and neck cancer: global burden and regional trends in India. Asian Pac J Cancer Prev, 15, 537-50. https://doi.org/10.7314/APJCP.2014.15.2.537
- Oze I, Matsuo K, Suzuki T, et al (2009). Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a japanese population. Cancer Epidemiol Biomarkers Prev, 18, 3097-102. https://doi.org/10.1158/1055-9965.EPI-09-0499
- Phukan RK, Chetia CK, Ali MS, Mahanta J (2001). Role of dietary habits in the development of oesophageal cancer in assam, the north-eastern region of india. Nutr Cancer, 39, 204-9. https://doi.org/10.1207/S15327914nc392_7
- Rai AK, Freddy AJ, Banerjee A, et al (2012). Distinct involvement of 9p21-24 and 13q14.1-14.3 chromosomal regions in raw betel-nut induced esophageal cancers in the state of Meghalaya, India. Asian Pac J Cancer Prev, 13, 2629-33. https://doi.org/10.7314/APJCP.2012.13.6.2629
- Segi M (1960). Cancer mortality for selected sites in 24 countries (1950-57). sendai, japan: department of public health, Tohoku University of Medicine.
- Sharma JD, Kataki AC, Vijay CR (2013). Population based incidence and patterns of cancer in kamrup urban cancer registry. India Natl Med J India, 26, 133-41.
- Sharma JD, Kalita M, Nirmolia T et al (2014). Cancer: scenario and relationship of different geographical areas of the globe with special reference to north east-india. Asian Pac J Cancer Prev, 15, 3721-9. https://doi.org/10.7314/APJCP.2014.15.8.3721
- Sharpe HK, McMahon AD, Raab GM, Brewster DH, Conway DI (2014). Association between socioeconomic factors and cancer risk: a population cohort study in Scotland (1991- 2006). Plos One, 9, 1-15.
- Takiar R, Shobana B (2009). Cancer incidence rates and the problem of denominators-a new approach in Indian cancer registries. Asian Pac J Cancer Prev, 10, 123-6.
- Takiar R, Nadayil D, Nandakumar A (2010). Projections of number of cancer cases in india (2010-2020) by cancer groups. Asian Pac J Cancer Prev, 11, 1045-9.
- Taranikanti M & Das B (2013). Risk factor profile of oral cancer patients in North East India. IJBR, 04, 615-622.
- NCRP (2013). Three year report of Population Based Cancer Registries 2009-2011. National Cancer Registry Programme (ICMR), National Centre for Disease Informatics & Research (NCDIR).
- Dietary and Demographical Risk Factors for Oesophageal Squamous Cell Carcinoma in the Eastern Anatolian Region of Turkey Where Upper Gastrointestinal Cancers are Endemic vol.16, pp.5, 2015, https://doi.org/10.7314/APJCP.2015.16.5.1913