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Polycystic Ovary Syndrome and Risk of Endometrial Cancer: a Mini-Review

  • Tokmak, Aytekin (Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital) ;
  • Kokanali, Mahmut Kuntay (Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital) ;
  • Guzel, Ali Irfan (Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital) ;
  • Kara, Aydan (Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital) ;
  • Topcu, Hasan Onur (Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital) ;
  • Cavkaytar, Sabri (Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital)
  • Published : 2014.09.15

Abstract

The polycystic ovary syndrome is the most common endocrinological disorder of reproductive age women with a prevalence of 5 to 8 %. The most common diagnostic criteria used for polycystic ovary syndrome are oligo- or an-ovulation, clinical and/ or biochemical signs of hyperandrogenism and polycystic ovaries. Hyperandrogenism results in increased estrogen levels and lack of cyclic progesterone due to anovulation and persistent stimulation of the endometrium may lead to endometrial hyperplasia or adenocarcinoma development. In this mini review, we aimed to evaluate the possible relationship between polycystic ovary syndrome and endometrial cancer.

Keywords

Polycystic ovary syndrome;risk;endometrial cancer

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