Concordance in Cervical HPV Detection between Hybrid Capture 2 and HPV GenoArray Tests

  • Zhang, Li (Department of Gynecology and Obstetrics, Sichuan University) ;
  • Lin, Yong (Laboratory of Molecular and Translational Medicine, West China Second Hospital, Sichuan University) ;
  • Li, Jin-ke (Department of Gynecology and Obstetrics, Sichuan University)
  • Published : 2014.06.15


HPV type-specific detection may promote cervical screening program and vaccination development worldwide. We conduct a study comparing HPV Hybrid capture II (HC II) Test and Hybribio GenoArray test, a newly developed HPV type-specific assay, in patients with cervical epithelial neoplasm. Results showed a good concordance in cervical HPV detection between two tests (kappa value 0.80, p<0.05, McNemar test). Our study may promote utilization of type-specific HPV detection that is helpful for cervical cancer screening and vaccination.



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