- Volume 15 Issue 12
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Lack of CHEK2 Gene Mutations in Differentiated Thyroid Carcinoma Patients using High Resolution Melting Analysis
- Fayaz, Shima (Department of Biochemistry, Pasteur Institute of Iran) ;
- Fard-Esfahani, Pezhman (Department of Biochemistry, Pasteur Institute of Iran) ;
- Torbati, Peyman Mohammadi (Department of Pathology, Labbafi-Nezhad Hospital, Shahid Beheshti Medical University)
- Published : 2014.06.30
Recently, mutations in the genes involved in cell cycle control, including CHEK2, are being considered as etiological factors in different kinds of cancers. The CHEK2 protein plays an important role in protecting damaged DNA from entering mitosis. In this study the potential effects of two common mutations
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