- Volume 15 Issue 4
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Relationship between Preoperative Serum CA15-3 and CEA Levels and Clinicopathological Parameters in Breast Cancer
- Moazzezy, Neda (Department of Molecular Biology, Pasteur Institute of Iran) ;
- Farahany, Tahereh Zarnoosheh (Department of Molecular Biology, Pasteur Institute of Iran) ;
- Oloomi, Mana (Department of Molecular Biology, Pasteur Institute of Iran) ;
- Bouzari, Saeid (Department of Molecular Biology, Pasteur Institute of Iran)
- Published : 2014.02.28
Background: CEA and CA 15.3 serum tumor markers are currently used in clinical practice for monitoring therapy. The aim of this study was to evaluate serum level of these markers among healthy females and invasive breast carcinoma (IBC) patients and to determine any relationships with clinicopathological factors. Materials and Methods: 60 Iranian females were enrolled in this study, 30 healthy and 30 diagnosed with breast cancer who had not received any preoperative chemotherapy or hormone therapy. Enzyme linked immunosorbent assays were used for the quantitative determination of the cancer associated antigens, CEA and MUC1 (CA15-3). Results: The serological levels of CEA and CA15-3 (
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