- Volume 15 Issue 4
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Clinicopathological Correlation of Cervical Carcinoma: A Tertiary Hospital Based Study
- Shruthi, Pannayanapalya Suresh (Department of Pathology and Obstetrics and Gynaecology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research) ;
- Kalyani, Raju (Department of Pathology and Obstetrics and Gynaecology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research) ;
- Lee, Jun Kai (Department of Pathology and Obstetrics and Gynaecology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research) ;
- Narayanaswamy, Mariyappa (Department of Pathology and Obstetrics and Gynaecology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research)
- Published : 2014.02.28
Background: To study the clinical presentation of cervical carcinoma correlating with histopathological findings in a tertiary hospital situated in the southern part of India catering to rural and semi-urban populations Materials and Methods: 199 cases histopathologically diagnosed as cervical cancer over a period of one year were considered for the study. Clinical details of the patients were noted with the help of semi-structured proforma. The data was analysed by descriptive analysis using SPSS software. Results: Out of 199 patients, 109 had moderately differentiated squamous cell carcinoma, 51 poorly differentiated and 35 well differentiated. Adenocarcinomas numbered only four. 121 cases were in the age group of 40-59 years, 59 in 60-80 years and 19 in 20-39 years. All four cases of adenocarcinoma were seen between 40-59 years. 95 (47.7%) cases were in women who had 4 or more children, 120 presented with white discharge, 89 with bleeding per vagina and 68 had constitutional symptoms. Most of the patients with adenocarcinoma presented with bleeding per vagina. 151 was in stage IIIB, 29 in stage IIB, 14 in stage IVA and 5 in stage IB. Conclusions: Screening of cervical cancer should be emphasised in women with white discharge especially in rural areas for early detection of dysplastic cells and reduce mortality and morbidity in productive age. In addition health education has to be given to women regarding the awareness of hygiene, risk factors and symptoms of cervical cancer.
Carcinoma cervix;clinicopathological correlation;Karnataka;India
- Greene FL, Compton CC, Fritz AG, et al (2006). AJCC Cancer Staging Atlas. 6th edition. Chicago, Springer. 249-58.
- Shastri SS (2010). Cervical cancer screening and early detection. The Times of India. Oct 21.
- The New York Times (2012). Health; Times Health Guide; Cervical Cancer Worldwide, Tuesday, December 18.
- Burk RD (2003). Human papilloma virus and the risk of cervical cancer. Asian J Obstet Gynaec Practice, 17, 24-9.
- Das BC, Gopalakrishna V, Hedau S, Katiyar S (2000). Cancer of uterine cervix and human papilloma virus infection. Current Science, 78, 52-6.
- Dikshit R, Gupta PC, Ramasundarahettige C, et al (2012). Cancer mortality in India: a nationally representative survey. The Lancet, 379, 1807-16. https://doi.org/10.1016/S0140-6736(12)60358-4
- Gagnon F (1950). Contribution to study of the etiology and prevention of cancer cervix. Am J Obstet Gynaec, 60, 516-22. https://doi.org/10.1016/0002-9378(50)90422-4
- Globocan (2008). International Agency for Research On Cancer, (IARC), Section Of Cancer Information.
- Gundrajakuppam L, Shanthi V, Rao NM, et al (2011). Clincopathological correlation of cervical carcinoma by Pap smear. J Biosci Tech, 2, 439-45.
- http://www.medindia.net/patients/patientinfo/cervicalcancerincidence. htm#ixzz2FO0IE8G3 (30/09/2013).
- Kaarthigeyan K (2012). Cervical cancer in India and HPV vaccination. Indian J Med Paediatr Onco, 33, 7-12. https://doi.org/10.4103/0971-5851.96961
- Kalyani R, Das D, Bindra Singh MS, Kumar H (2010). Cancer profile in the department of pathology of Sri Devaraj Urs Medical College: a ten years study. Indian J Cancer, 47, 160-5. https://doi.org/10.4103/0019-509X.63011
- Misra JS, Srivastava S, Singh U, Srivastava (2009). Risk-factors and strategies for control of carcinoma cervix in India: Hospital based cytological screening experience of 35 years. Indian J Cancer, 46, 155-9. https://doi.org/10.4103/0019-509X.49155
- Satija A (2012). Cervical cancer in India. South Asia centre for chronic disease. http://sancd.org/uploads/pdf/cervical_ cancer.pdf.
- Aswathy S, Quereshi MA, Kurian B, Leelamoni K (2012). Cervical cancer screening: current knowledge and practice among women in a rural population of Kerala, India. Indian J Med Res, 136, 205-10.
- Berrington de Gonza'lez A, Sweetland S, Green J (2004). Comparison of risk factors for squamous cell and adenocarcinomas of the cervix: a meta-analysis. Br J Cancer, 90, 1787-91. https://doi.org/10.1038/sj.bjc.6601764
- Bradley JM, Krishnansu ST (2007). Invasive cervical cancer. in: disaia, creasman editors. clinical gynecologic oncology. 7th edition. China: Mosby Elsevier, 55-124.
- High Dose Rate Brachytherapy in Two 9 Gy Fractions in the Treatment of Locally Advanced Cervical Cancer - a South Indian Institutional Experience vol.16, pp.16, 2015, https://doi.org/10.7314/APJCP.2015.16.16.7167