- Volume 15 Issue 4
DOI QR Code
Is the Correlation between Papanicolaou Smear and Histopathology Results Affected by Time to Colposcopy?
- Meevasana, Vorachart (Department of Obstetrics and Gynaecology, Thammasat University) ;
- Suwannarurk, Komsun (Department of Obstetrics and Gynaecology, Thammasat University) ;
- Chanthasenanont, Athita (Department of Obstetrics and Gynaecology, Thammasat University) ;
- Tanprasertkul, Chamnan (Department of Obstetrics and Gynaecology, Thammasat University) ;
- Bhamarapravatana, Kornkarn (Department of Preclinical science, Faculty of Medicine, Thammasat University) ;
- Pattaraarchachai, Janya (Chulabhorn International College of Medicine, Thammasat University)
- Published : 2014.02.28
Background: Time to colposcopy (TC) after abnormal Pap smears was evaluated for influence on cytohistologic correlation (CHC). Materials and Methods: This retrospective study assessed the correlation between TC and CHC of women who had abnormal Pap smears. Colposcopic chart review included participants from 2010-2013 who attended a colposcopic clinic, Thammasat University Hospital, Thailand. Results: Four hundred and sixty cases who had abnormal Pap smears were recruited. Pap reports were atypical smears with low grade squamous intraepithelial lesion (SIL), high grade SIL and cancer at 339, 114 and 7 cases, respectively. One hundred and twenty four patients underwent loop electrosurgical excision procedure (LEEP). A half of the cases were colposcopically examined within 1-2 months after abnormal Pap collection. CHC was 88 percent and not affected at all by TC. Subjects who attended cervical cancer screening from affiliated health providers had shorter TC than those screened in our tertiary hospital. Conclusions: Time to colposcopy with abnormal Pap smears conducted at Thammasat University Hospital had a highest frequency of 42 days, in line with the literature. Length of TC does not affect the correlation between Pap and histopathologic reports. A longer waiting period for colposcopy did not alter progression or regression of the disease.
- Campion MJ, Berek JS, Hacker NF, et al (2010). Berek and Hacker's Gynecologic Oncology. 5th ed. Lippincott: William & Wilkins, 267-340.
- Saayman F, Van Gelderen CJ, Michelow P, et al (2013). Effect of 2 referral intervals on diagnostic discordance between cytology and histopathology at a colposcopy clinic. Int J Gynaecol Obstet, 120, 257-61.
- Tahseen S, Reid PC (2008). Psychological distress associated with colposcopy: patients' perception. Eur J Obstet Gynecol Reprod Biol, 139, 90-4. https://doi.org/10.1016/j.ejogrb.2007.09.001
- Baranoski AS, Stier EA (2012). Factors associated with time to colposcopy after abnormal Pap testing in HIV-infected women. J Women's Health, 21, 418-24. https://doi.org/10.1089/jwh.2011.3046
- Carns B, Fadare O (2008). Papanicolaou test in the detection of high-grade cervical lesions: a re-evaluation based on cytohistologic non-correlation rates in 356 concurrently obtained samples. Int J Clin Exp Pathol, 1, 285-90.
- Ferlay J, Shin HR, Bray F, et al (2010). 2008 Estimates of worldwide burden of cancer. Int J Cancer, 127, 2893-917. https://doi.org/10.1002/ijc.25516
- Kuo TM, Benard VB, Berkman ND, et al (2010). Richardson LC. Timing of colposcopy after cervical cytological abnormalities. Obstet Gynecol, 115, 629-36. https://doi.org/10.1097/AOG.0b013e3181cec0b5
- Panyanupap A, Thaweekul Y, Poomtavorn Y, et al (2011). Prevalence of high-grade cervical intraepithelial neoplasia (CIN) in the patients with atypical squamous cells of undetermined significance (ASC-US) Pap smears: hospital based, dynamic population area. J Med Assoc Thai, 94, 159-63.
- Poomtavorn Y, Himakhun W, Suwannarurk K, et al (2013). Cytohistologic discrepancy of high-grade squamous intraepithelial lesions in Papanicolaou smears. Asian Pac J Cancer Prev, 14, 599-602. https://doi.org/10.7314/APJCP.2013.14.1.599
- Retrospective View of Two Years of Colposcopy Practice in a Gynecologic Clinic in Cotonou vol.07, pp.02, 2017, https://doi.org/10.4236/ojog.2017.72024