- Volume 15 Issue 1
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Haematologic Parameters in Metastatic Colorectal Cancer Patients Treated with Capecitabine Combination Therapy
- Inanc, Mevlude (Kayseri Training and Research Hospital, Erciyes University) ;
- Duran, Ayse Ocak (Medical Oncology Department, Erciyes University) ;
- Karaca, Halit (Medical Oncology Department, Erciyes University) ;
- Berk, Veli (Medical Oncology Department, Erciyes University) ;
- Bozkurt, Oktay (Medical Oncology Department, Erciyes University) ;
- Ozaslan, Ersin (Medical Oncology Department, Erciyes University) ;
- Ozkan, Metin (Medical Oncology Department, Erciyes University)
- Published : 2014.01.15
Background: The standard treatment in the metastatic colorectal cancer consists of 5-FU based infusional regimens. However, with oral fluoropyrimidines, equal tumor responses may be obtained. Capecitabine causes macrocytosis of the cells by inhibition of DNA synthesis. In this context, a relationship was found between mean corpuscular volume (MCV) and response to therapy in breast cancer patients treated with Capecitabine, but whether this relationship also pertains in colorectal cancer has not been established. Materials and Methods: A total of 102 metastatic colorectal cancer patients treated with a oxaliplatin (XELOX)
Colorectal cancer;chemotherapy response;MCV;PLT;NLR
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- Lack of Prognostic Value of Mean Corpuscular Volume with Capecitabine Therapy in Metastatic Breast Cancer vol.15, pp.6, 2014, https://doi.org/10.7314/APJCP.2014.15.6.2501
- Diagnostic and prognostic roles of the mean platelet volume in malignant tumors: a systematic review and meta-analysis vol.27, pp.8, 2016, https://doi.org/10.3109/09537104.2016.1169265
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