- Volume 15 Issue 1
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Haematologic Parameters in Metastatic Colorectal Cancer Patients Treated with Capecitabine Combination Therapy
- Inanc, Mevlude ;
- Duran, Ayse Ocak ;
- Karaca, Halit ;
- Berk, Veli ;
- Bozkurt, Oktay ;
- Ozaslan, Ersin ;
- Ozkan, Metin
- Published : 2014.01.15
Background: The standard treatment in the metastatic colorectal cancer consists of 5-FU based infusional regimens. However, with oral fluoropyrimidines, equal tumor responses may be obtained. Capecitabine causes macrocytosis of the cells by inhibition of DNA synthesis. In this context, a relationship was found between mean corpuscular volume (MCV) and response to therapy in breast cancer patients treated with Capecitabine, but whether this relationship also pertains in colorectal cancer has not been established. Materials and Methods: A total of 102 metastatic colorectal cancer patients treated with a oxaliplatin (XELOX)
Colorectal cancer;chemotherapy response;MCV;PLT;NLR
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