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Influences of Korean Haw (Crataegus pinnatifida BUNGE) on Lipid Concentration in Hypercholesterolemia

한국산 산사(Crataegus pinnatifida BUNGE)가 고콜레스테롤혈증 지질농도 변화에 미치는 영향

  • Kim, Han-Soo (Department of Food Science & Technology, Pusan National University) ;
  • Kim, Min-A (Department of Food Science & Technology, Pusan National University) ;
  • Jang, Seong-Ho (Department of Bioenviromental Energy, Pusan National University)
  • 김한수 (부산대학교 식품공학과) ;
  • 김민아 (부산대학교 식품공학과) ;
  • 장성호 (부산대학교 바이오환경에너지학과)
  • Received : 2014.01.16
  • Accepted : 2014.02.19
  • Published : 2014.05.30

Abstract

This study was conducted to observe the influences of Crataegus pinnatifida BUNGE extract on lipid concentration in hypercholesterolemic rats (Sprague Dawley, male) fed the experimental diets for 5 weeks. Body weight gain was remarkably lower in the Crataegus pinnatifida BUNGE extract intake group than in the hypercholesterolemic rats. Total cholesterol concentration was remarkably lower in the extract of Crataegus pinnatifida BUNGE supplement in hypercholesterolemic rats than in the hypercholesterolemic model. Whereas, concentrations of HDL-cholesterol, ratio of HDL-cholesterol concentration to total cholesterol were remarkably higher in the extract of Crataegus pinnatifida BUNGE supplement in hypercholesterolemic rats than in the hypercholesterolemic model. Atherosclerotic index (AI), cardiac risk factor (CRF) were remarkably lower in the extract of Crataegus pinnatifida BUNGE supplement in hypercholesterolemic rats than in the hypercholesterolemic model. From the above research, Crataegus pinnatifida BUNGE extract was effective on the lipid concentrations in sera of dietary hypercholesterolemic rats.

Keywords

Crataegus pinnatifida BUNGE;Hypercholesterolemia;Lipid;Atherosclerotic index;Cardiac risk factor

Acknowledgement

Supported by : 부산대학교

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