A Systematic Review of Cervical Cancer Incidence and Mortality in the Pacific Region

  • Obel, J. (Department of Obstetrics and Gynaecology, Hvidovre Hospital) ;
  • Souares, Y. (Research Evidence and Information Program, Public Health Division, Secretariat of the Pacific Community) ;
  • Hoy, D. (Research Evidence and Information Program, Public Health Division, Secretariat of the Pacific Community) ;
  • Baravilala, W. (Asia Pacific Regional Office, United Nations Population Fund) ;
  • Garland, S.M. (Royal Women's Hospital, Royal Children's Hospital, Murdoch Childrens Research Institute, Department of Obstetrics and Gynaecology, University of Melbourne) ;
  • Kjaer, S.K. (Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Gynecologic Clinic, Rigshospitalet, University of Copenhagen) ;
  • Roth, A. (Research Evidence and Information Program, Public Health Division, Secretariat of the Pacific Community)
  • Published : 2014.11.28


This study provides the first systematic literature review of cervical cancer incidence and mortality as well as human papillomavirus (HPV) genotype prevalence among women with cervical cancer in the Pacific Island countries and territories. The cervical cancer burden in the Pacific Region is substantial, with age standardized incidence rates ranging from 8.2 to 50.7 and age standardized mortality rate from 2.7 to 23.9 per 100,000 women per year. The HPV genotype distribution suggests that 70-80% of these cancers could be preventable by the currently available bi- or quadrivalent HPV vaccines. There are only few comprehensive studies examining the epidemiology of cervical cancer in this region and no published data have hitherto described the current cervical cancer prevention initiatives in this region.


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