DOI QR코드

DOI QR Code

Human Papillomavirus Vaccination Acceptability among Female University Students in South Africa

  • Hoque, Muhammad Ehsanul (Graduate School of Business and Leadership, University of KwaZulu-Natal) ;
  • Ghuman, Shanaz (Department of Community Health Studies, Durban University of Technology) ;
  • Van Hal, Guido (Medical Sociology and Health Policy, University of Antwerp)
  • Published : 2013.08.30

Abstract

Background: The objectives of this present study were to assess the awareness of cervical cancer and its risk factors among female undergraduates in South Africa, and to determine the their level of acceptability of Human Papillomavirus (HPV) vaccination. Materials and Methods: This cross-sectional study was conducted in March 2013 among 440 full time undergraduate female students. Results: Of those students who never had sex (n=163), 96 (58.9%) had ever heard of cervical cancer and only 12 students (12.5%) knew that HPV causes cervical cancer. More than a third (35.4%) of the students correctly said that sexual intercourse before age of 18 years is a risk factor for cervical cancer and 55.2% of the students knew about the Pap smear test which is used for screening cervical cancer. The majority (77.3%) were willing to accept HPV vaccination. Results revealed that students who knew about the Pap smear test, and were aware that having multiple sex partners, sexual intercourse before the age of 18 years, smoking and having contracted any STDs are risk factors for cervical cancer were more likely to accept HPV vaccination compared to other groups. Conclusions: The general knowledge of South African female university students about cervical cancer is not sufficient but they have positive attitudes toward getting vaccinated with the HPV vaccine.

Keywords

Cervical cancer;HPV vaccination;acceptability;university student;South Africa

References

  1. Aniebue PN, Aniebue UU (2010). Awareness and Practice of Cervical Cancer Screening Among Female Undergraduate Students in a Nigerian University. J Canc Educ, 25, 106-8. https://doi.org/10.1007/s13187-009-0023-z
  2. Bothaa MH, Dochezb C (2012). Introducing human papillomavirus vaccines into the health system in South Africa. Vaccine, 30, 28-34. https://doi.org/10.1016/j.vaccine.2012.03.032
  3. Denny LA, Franceschi S, de Sanjose S, et al (2012). Human Papillomavirus, Human Immunodeficiency Virus and Immunosuppression. Vaccine, 30, 168-74. https://doi.org/10.1016/j.vaccine.2011.11.030
  4. Di Giuseppe G, Abbate R, Liguori G, et al (2008). Human papillomavirus and vaccination: knowledge, attitudes, and behavioural intention in adolescents and young women in Italy. Br J Cancer, 99, 225-9. https://doi.org/10.1038/sj.bjc.6604454
  5. Gerend MA, Magloire ZF (2008). Awareness, knowledge, and b eliefs about human papillomavirus in a racially diverse sample of young adults. J Adolesc Health, 42, 237-42. https://doi.org/10.1016/j.jadohealth.2007.08.022
  6. Goldie SJ, O’Shea M, Campos NG, et al (2008). Health and economic outcomes of HPV 16,18 vaccination in 72 GAVI-eligible countries. Vaccine, 26, 4080-93. https://doi.org/10.1016/j.vaccine.2008.04.053
  7. Hershey JH, Velez LF (2009). Public health issues related to HPV vaccination. J Public Health Manag Pract, 15, 384-92 https://doi.org/10.1097/PHH.0b013e3181a23de6
  8. Hoover DR, Carfioli B, Moench EA (2000). Attitudes of adolescent/young adult women toward human papilloma virus vaccination and clinical trials. Health Care Women Int, 21, 375-91. https://doi.org/10.1080/07399330050082227
  9. Hopenhayn C, Christian A, Christian WJ, et al (2007). Human papillomavirus vaccine: Knowledge and attitudes in two Appalachian Kentucky counties. Cancer Causes and Control, 18, 627-34. https://doi.org/10.1007/s10552-007-9007-7
  10. Hopkins TG, Wood N (2013). Female human papillomavirus (HPV) vaccination: Global uptake and the impact of attitudes. Vaccine, (In Press). Available at: http://dx.doi.org/10.1016/j.vaccine.2013.01.028 https://doi.org/10.1016/j.vaccine.2013.01.028
  11. Hoque E, Hoque M (2009). Knowledge of and attitude towards cervical cancer among female university students in South Africa. South Afr J Epidemiol Infect, 24, 21-4.
  12. Hsu YY, Fetzer SJ, Hsu KF, et al (2009). Intention to obtain human papillomavirus vaccination among Taiwanese undergraduate women. Sex Trans Dis, 36, 686-92. https://doi.org/10.1097/OLQ.0b013e3181ad28d3
  13. Iliyasu Z, Abubakar IS, Aliyu MH, et al (2010). Cervical cancer risk perception and predictors of human papilloma virus vaccine acceptance among female university students in northern Nigeria. J Obstet Gynaecol, 30, 857-62. https://doi.org/10.3109/01443615.2010.511724
  14. Kamzol W, Jaglarz K, Tomaszewski KA, et al (2013). Assessment of knowledge about cervical cancer and its prevention among female students aged 17-26 years. Eur J Obstet Gynecol Reprod Biol, 166, 196-203. https://doi.org/10.1016/j.ejogrb.2012.10.019
  15. Kohli M, Ferko N, Martin A, et al (2007). Estimating long-term impact of a prophylactic human papillomavirus 16/18 vaccine on the burden of cervical cancer in the UK. Br J Cancer, 96, 143-50. https://doi.org/10.1038/sj.bjc.6603501
  16. Kwan TT, Chan KK, Yip AM, et al (2009). Acceptability of human papillomavirus vaccination among Chinese women: Concerns and implications. BJOG, 116, 501-10. https://doi.org/10.1111/j.1471-0528.2008.01988.x
  17. Lehtinen M, Paavonen J, Wheeler CM, et al (2012). Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial. Lancet Oncol, 13, 89-99. https://doi.org/10.1016/S1470-2045(11)70286-8
  18. Lenselink CH, Schmeink CE, Melchers WJG, et al (2008). Young adults and acceptance of the human papillomavirus vaccine. Public Health, 122, 1295-301. https://doi.org/10.1016/j.puhe.2008.02.010
  19. Marek E, Dergez T, Rebek-Nagy G, et al (2011). Adolescents' awareness of HPV infections and attitudes towards HPV vaccination 3 years following the introduction of the HPV vaccine in Hungary. Vaccine, 29, 8591-8. https://doi.org/10.1016/j.vaccine.2011.09.018
  20. Marlow LAV, Waller J, Wardle J (2007). Parental attitudes to pre-pubertal HPV vaccination. Vaccine, 25, 1945-52. https://doi.org/10.1016/j.vaccine.2007.01.059
  21. Mortensen (2010). Drivers and barriers to acceptance of human-papillomavirus vaccination among young women: a qualitative and quantitative study. BMC Public Health, 10, 68. https://doi.org/10.1186/1471-2458-10-68
  22. Mqoqi N, Kellett P, Sitas F, Jula M (2004). Incidence of histologically diagnosed cancer in South Africa, 1998-1999. Johannesburg: National Cancer Registry of South Africa, National Health Laboratory Service.
  23. Munoz N, Jacquard AC (2008). What should be known for the introduction of an HPV vaccine? [Article in French]. Presse Med, 37, 1377-90. https://doi.org/10.1016/j.lpm.2008.04.008
  24. Nobbenhius M, Helmerhorst T, van den Brule A, et al (2001). Cytological regression and clearance of high-risk human papillomavirus in women with abnormal cervical smear. Lancet, 358, 1782-3. https://doi.org/10.1016/S0140-6736(01)06809-X
  25. Paavonen J, Naud P, Salmeron J, et al (2009). Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women. Lancet, 374, 301-14. https://doi.org/10.1016/S0140-6736(09)61248-4
  26. Saha A, Nag Chaudhury A, Bhowmik P, et al (2010). Awareness of cervical cancer among female students of premier colleges in Kolkata, India. Asian Pac J Cancer Prev, 11, 1085-90.
  27. Schiffman M, Castle PE, Jeronimo J, et al (2007). Human papillomavirus and cervical cancer. Lancet, 370, 890-907. https://doi.org/10.1016/S0140-6736(07)61416-0
  28. Schiffman M, Wacholder S (2012). Success of HPV vaccination is now a matter of coverage. Lancet Oncol, 13, 10-2. https://doi.org/10.1016/S1470-2045(11)70324-2
  29. Seoud M, Tjalma WA, Ronsse V (2011). Cervical adenocarcinoma: moving towards better prevention. Vaccine, 29, 9148-58. https://doi.org/10.1016/j.vaccine.2011.09.115
  30. Smith JS, Lindsay L, Hoots B, et al (2007). Human papillomavirus type distribution in invasive cervical cancer and high-grade cervical lesions: a meta-analysis update. Int J Cancer, 121, 621-32. https://doi.org/10.1002/ijc.22527
  31. WHO/ICO Information Centre on HPV and Cervical Cancer (HPV Information Centre). Human Papil-lomavirus and Related Cancers in South Africa. Summary Report 2010. Available at: www.who.int/hpvcentre [Date accessed: 15 January 2013].
  32. Wong LP, Sam IC (2010). Ethnically diverse female university students' knowledge and attitudes toward human papillomavirus (HPV), HPV vaccination and cervical cancer. Eur J Obstet Gynecol Reprod Biol, 148, 90-5. https://doi.org/10.1016/j.ejogrb.2009.10.002
  33. World Health Organization (2009). Human papillomavirus vaccines. WHO position paper. Weekly Epidemiological Record, 84, 118-31.

Cited by

  1. Differencies in Risk Factors for Cervical Dysplasia with the Applied Diagnostic Method in Serbia vol.15, pp.16, 2014, https://doi.org/10.7314/APJCP.2014.15.16.6697
  2. Attitudes and Practice of Cervical Cancer Screening among Female University Students from 25 Low, Middle Income and Emerging Economy Countries vol.15, pp.17, 2014, https://doi.org/10.7314/APJCP.2014.15.17.7235
  3. Knowledge, Attitudes and Beliefs about Cervical Cancer and Human Papilloma Virus Vaccination with Related Factors in Turkish University Students vol.15, pp.8, 2014, https://doi.org/10.7314/APJCP.2014.15.8.3699
  4. Knowledge of Human Papillomavirus Infection, Cervical Cancer and Willingness to pay for Cervical Cancer Vaccination among Ethnically Diverse Medical Students in Malaysia vol.16, pp.14, 2015, https://doi.org/10.7314/APJCP.2015.16.14.5733
  5. Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective vol.16, pp.1, 2016, https://doi.org/10.1186/s12905-016-0306-6
  6. Knowledge and Attitudes of Medical and Non-Medical Turkish University Students about Cervical Cancer and HPV Vaccination vol.17, pp.1, 2016, https://doi.org/10.7314/APJCP.2016.17.1.299
  7. Knowledge of HPV and acceptability of HPV vaccine among women in western China: a cross-sectional survey vol.18, pp.1, 2018, https://doi.org/10.1186/s12905-018-0619-8
  8. A review of knowledge and attitudes of young people on cervical cancer and HPV vaccination pp.1613-2238, 2019, https://doi.org/10.1007/s10389-018-01012-w