- Volume 14 Issue 7
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Effect of 5-aza-2'-deoxycytidine on Cell Proliferation of Non-small Cell Lung Cancer Cell Line A549 Cells and Expression of the TFPI-2 Gene
- Dong, Yong-Qiang (Department of Cardio-Thoracic Surgery, Wuhan General Hospital of Guangzhou Military Command) ;
- Liang, Jiang-Shui (Southern Medical University Affiliated Clinical College of Wuhan) ;
- Zhu, Shui-Bo (Department of Cardio-Thoracic Surgery, Wuhan General Hospital of Guangzhou Military Command) ;
- Zhang, Xiao-Ming (Department of Cardio-Thoracic Surgery, Wuhan General Hospital of Guangzhou Military Command) ;
- Ji, Tao (Department of Cardio-Thoracic Surgery, Wuhan General Hospital of Guangzhou Military Command) ;
- Xu, Jia-Hang (Department of Cardio-Thoracic Surgery, Wuhan General Hospital of Guangzhou Military Command) ;
- Yin, Gui-Lin (Southern Medical University Affiliated Clinical College of Wuhan)
- Published : 2013.07.30
Objective: The present study employed 5-aza-2'-deoxycytidine (5-Aza-CdR) to treat non-small cell lung cancer (NSCLC) cell line A549 to investigate the effects on proliferation and expression of the TFPI-2 gene. Methods: Proliferation was assessed by MTT assay after A549 cells were treated with 0, 1, 5, 10
5-Aza-CdR;TFPI-2;DNA methylation;non-small cell lung cancer
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