- Volume 14 Issue 5
DOI QR Code
Change in Adiponectin and Oxidative Stress after Modifiable Lifestyle Interventions in Breast Cancer Cases
- Karimi, Niloofar (College of Physical Education and Sport Sciences, Department of Sport Physiology, University of Mazandaran) ;
- Roshan, Valiollah Dabidi (College of Physical Education and Sport Sciences, Department of Sport Physiology, University of Mazandaran)
- Published : 2013.05.30
Background: Breast cancer is one of the most frequent diseases in women today. Little information exists on modifiable lifestyle factors including effects of ginger supplements (as an anti-oxidant and anti-inflammatory herbal) and water-based exercise on biomarkers related to oxidative stress such as malondialdehyde (MDA), nitric oxide (NO) and glutathione peroxidase (GPx) and adiponectin in obese women with breast cancer. The aim of this study was to determine the single and concomitant effect of 6-wks water-based exercise and oral ginger supplement on the aforesaid markers in obese women with breast cancer. Materials and Methods: Forty women diagnosed with breast cancer (
- Afshari A, Shirpoor A, Farshid A, et al (2007). The effect of ginger on diabetic nephropathy, plasma antioxidant capacity and lipid peroxidation. Food Chemistry, 101, 148-53. https://doi.org/10.1016/j.foodchem.2006.01.013
- Atashak S, Peeri M, Azarbayjani M, et al (2011). Obesity related cardiovascular risk factors after long- term resistance training and ginger supplementation. J Sports Sci and Med, 10, 685-691.
- Barbaric M, Brooks E, Moore L, Cheifetz O (2010). Effects of physical activity on cancer survival: a systematic review. Physiother Can, 62, 25-34. https://doi.org/10.3138/physio.62.1.25
- Blair C, Morey M, Desmond R, et al (2013). Cross-sectional & longitudinal associations between light-intensity physical activity & physical function among cancer survivors. Cancer Epidemiol Biomarkers Prev, 22, 475.
- Campbell T, Gross M, Potter J, et al (2010). Effect of exercise on oxidative stress: a 12-month randomized, controlled trial. Med Sci Sports Exerc, 42, 1448-53. https://doi.org/10.1249/MSS.0b013e3181cfc908
- Carole M, City C, Lisa K, Susan D, Reid H (2007). Effects of supervised exercise training on cardiopulmonary function and fatigue in breast cancer survivors during and after treatment. Cancer, 110, 918-25. https://doi.org/10.1002/cncr.22862
- Christopher D, Matthew P, David J, Patrick J (2010). Ginger (Zingiberofficinale) reduces muscle pain caused by eccentric exercise. The J Pain, 11, 894-903. https://doi.org/10.1016/j.jpain.2009.12.013
- Cleary MP, Grossmann ME, Ray A (2010). Effect of obesity on breast cancer development. Veterinary Pathology, 47, 202-213. https://doi.org/10.1177/0300985809357753
- Donnelly JE, Blair SN, Jakicic JM, et al (2009). Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc, 41, 459-71.
- Fujita K, Nishizawa H, Funahashi T, et al (2006). Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome, Circ J, 70, 1437-42. https://doi.org/10.1253/circj.70.1437
- Gago-Dominguez M, Castelao JE, Pike MC, Sevanian A, Haile R (2005). Role of lipid peroxidation in the epidemiology and prevention of breast cancer. Cancer Epidemiol Biomarkers Prev, 14, 2829-39. https://doi.org/10.1158/1055-9965.EPI-05-0015
- Goodwin PJ, Stambolic V (2011). Obesity and insulin resistance in breast cancer ? chemoprevention strategies with a focus on metformin. The Breast, 3, 31-5.
- Habib SHM, Makpol S, Hamid NA, et al (2008). Ginger extract (Zingiber officinale) hasanti- cancerand anti-inflammatory effects on ethionine-induced hepatomarats. Clinics, 63, 807-13.
- Harliansyah AH, Noor AM, Wan ZWN, Yasmin AMY (2005). Effects of zingiber officinale on superoxide dismutase, glutathione peroxidase, catalase, glutathione and malondialdehyde content in HepG2 Cell Line. Malaysian J Biochemistry and Molecular Biology, 11, 36-41.
- Ling H, Yang H, Tan SH, et al (2010). 6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-kB activation. BJP, 1763-77.
- Lof M, Bergstrom K, Weiderpass E (2012). Physical activity and biomarkers in breast cancer survivors: a systematic review. Maturitas, 9,5806.
- Loprinzi P, Cardinal B, Smit E, Winters-Stone K (2012). Physical activity and breast cancer risk. J Exercise Sci & Fitness, 10, 1-7. https://doi.org/10.1016/j.jesf.2012.04.004
- Mantzoros C, Petridou E, Dessypris N et al (2004). Adiponectin and breast cancer risk. J Clinical Endocrinology and Metabolism, 89, 1102-7. https://doi.org/10.1210/jc.2003-031804
- Margot P, Cleary E, Michael E, Grossman N (2009). Minireview: Obesity and Breast Cancer: The Estrogen Connection. Endocrinology, 150, 2537-42. https://doi.org/10.1210/en.2009-0070
- Meredith-Jones K, WatersD, Legge M, Jones L (2011). Upright water-based exercise to improve cardiovascular and metabolic health: a qualitative review. Complementary Therapies in Med, 19, 93-103. https://doi.org/10.1016/j.ctim.2011.02.002
- Michael E, Amitabha R, Katai J, et al (2010). Obesity and breast cancer: status of leptin and adiponectin in pathological processes. Cancer Metastasis Rev, 29, 6410-53.
- Panis C, Victorino VJ, Herrera AC, et al (2012). Differential oxidative status and immune characterization of the early and advanced stages of human breast cancer. Breast Cancer Res Treat, 133, 881-8. https://doi.org/10.1007/s10549-011-1851-1
- Rajneesh CP, Manimaran A, Sasikala KR, Adaikappan P (2008). Lipid peroxidation and antioxidant status in patients with breast cancer. Singapore Med J, 49, 640.
- Sheri J, Shira I, Paul B (2011). The relationship of psychosocial factors to mammograms, physical activity, and fruit and vegetable consumption among sisters of breast cancer patients. Int J Women's Health, 3, 257-63.
- Suzana S, Normah H, Fatimah A, et al (2008). Antioxidants Intake And Status, And Oxidative Stress In Relation To Breast Cancer Risks: A Case-Control Study. Asian Pac J Cancer Prev, 9, 343-50.
- Takeshima N, Rogers ME, Watanabe E, et al (2002). Water-based exercise improves health related aspects of fitness in older women. Med Sci Sports Exerc, 32, 544-51.
- Yaacob N, Hamzah N, Kamal M, et al (2010). Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro. BMC Complementary Alternative Med, 10, 42. https://doi.org/10.1186/1472-6882-10-42
- Yasuka I, Yuri M, Masayoshi Y, et al (2008). 6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-a mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes. Biochem Biophys Res Communications, 373, 429-34. https://doi.org/10.1016/j.bbrc.2008.06.046
- Serum Adiponectin but not Leptin at Diagnosis as a Predictor of Breast Cancer Survival vol.15, pp.15, 2014, https://doi.org/10.7314/APJCP.2014.15.15.6137
- Serum Adiponectin Level Association with Breast Cancer Risk: Evidence from a Case-Control Study vol.16, pp.12, 2015, https://doi.org/10.7314/APJCP.2015.16.12.4945
- Spices for Prevention and Treatment of Cancers vol.8, pp.8, 2016, https://doi.org/10.3390/nu8080495
- Adiponectin Potentially Contributes to the Antidepressive Effects of Baduanjin Qigong Exercise in Women with Chronic Fatigue Syndrome-Like Illness vol.26, pp.3, 2017, https://doi.org/10.3727/096368916X694238
- Effects of physical exercise after treatment of early breast cancer: systematic review and meta-analysis vol.170, pp.3, 2018, https://doi.org/10.1007/s10549-018-4786-y