- Volume 14 Issue 4
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Genotoxicity and Interference with Cell Cycle Activities by an Ethanolic Extract from Thai Plumbago indica Roots in Human Lymphocytes in vitro
- Thitiorul, Sumon (Department of Preclinical Science, Faculty of Medicine, Thammasat University) ;
- Ratanavalachai, Treetip (Department of Preclinical Science, Faculty of Medicine, Thammasat University) ;
- Tanuchit, Sermkiat (Research Center, Faculty of Medicine, Thammasat University) ;
- Itharat, Arunporn (Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University) ;
- Sakpakdeejaroen, Intouch (Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University)
- Published : 2013.04.30
In Thai traditional medicine, Plumbago indica or Jetamul-Pleung-Dang in Thai is known to have health benefit especially for anti-inflammatory, antibacterial, and antitumor activities. However, the mechanisms of its action are still uncertain. One of which might be genotoxic effects. In the present study, we investigated the genotoxicity of an ethanolic extract of Plumbago indica root (EEPIR) by sister chromatid exchange (SCE) assay in human lymphocytes. Results have shown that all treatments with EEPIR (
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