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DOI QR Code

Anti-obesity effects of black ginseng extract in high fat diet-fed mice

  • Lee, Mi Ra (Daedeok Bio Corporation Research and Development center) ;
  • Kim, Byung Chan (Department of Food Science and Technology, Chungnam National University) ;
  • Kim, Ran (Department of Food Science and Technology, Chungnam National University) ;
  • Oh, Hyun In (Department of Biotechnology, Yonsei University) ;
  • Kim, Hyun Kyoung (Daedeok Bio Corporation Research and Development center) ;
  • Choi, Kang Ju (Daedeok Bio Corporation Research and Development center) ;
  • Sung, Chang Keun (Department of Food Science and Technology, Chungnam National University)
  • Received : 2013.02.25
  • Accepted : 2013.04.29
  • Published : 2013.07.15

Abstract

Black ginseng is produced by a repeated steaming process. The aim of this study was to investigate the anti-obesity effects of black ginseng ethanol extract (BG-EE) in high fat (HF) diet-fed mice. Two groups were fed either a normal control (NC) diet or a HF diet (45% kcal fat). The other three groups were given a HF diet supplemented with 1% BG-EE, 3% BG-EE, and 5% BG-EE for 12 wk. The anti-obesity effects of the BG-EE supplement on body weight, the development of fat mass, and lipid mechanisms were assessed in obese mice. HF-induced hyperlipidemia, fat accumulation in the liver, and white adipose tissues were reduced after BG-EE supplementation. Total fecal weight and the amount of fecal fat excretion also were increased after BG-EE supplementation. These results suggest that BG-EE may be useful to ameliorate HF-induced obesity through the strong inhibition of fat digestion.

Keywords

Panax ginseng;Black ginseng;High fat diet;Obesity;Hyperlipidemia

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