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Novel Synthesis of 3-Phenyl-chromen-4-ones Using N-Heterocyclic Carbene as Organocatalyst: An Efficient Domino Catalysis Type Approach

  • Mishra, Priya (Environmentally Benign Synthesis Lab., Department of Chemistry, University of Allahabad) ;
  • Singh, Sarita (Environmentally Benign Synthesis Lab., Department of Chemistry, University of Allahabad) ;
  • Ankit, Preyas (Environmentally Benign Synthesis Lab., Department of Chemistry, University of Allahabad) ;
  • Fatma, Shahin (Environmentally Benign Synthesis Lab., Department of Chemistry, University of Allahabad) ;
  • Singh, Divya (Environmentally Benign Synthesis Lab., Department of Chemistry, University of Allahabad) ;
  • Singh, Jagdamba (Environmentally Benign Synthesis Lab., Department of Chemistry, University of Allahabad)
  • Received : 2012.11.22
  • Accepted : 2013.01.09
  • Published : 2013.04.20

Abstract

Herein is reported a simple and efficient synthesis of isoflavones starting from various substituted phenacyl bromides and salicylaldehydes in presence of NHC. The mechanism involved domino catalysis type approach with consumption and regeneration of catalyst in two catalytic cycles. This method proved to be very lucrative and gives very good yield. The method described here represents an environmentally benign alternative to classical approach.

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Cited by

  1. ChemInform Abstract: Novel Synthesis of 3-Phenyl-chromen-4-ones Using N-Heterocylic Carbene as Organocatalyst: An Efficient Domino Catalysis Type Approach. vol.44, pp.40, 2013, https://doi.org/10.1002/chin.201340146