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Levels of Serum Trace Elements in Renal Cell Carcinoma Cases

  • Pirincci, Necip (Department of Urology, Faculty of Medicine, Yuzuncu Yil University) ;
  • Gecit, Ilhan (Department of Urology, Faculty of Medicine, Yuzuncu Yil University) ;
  • Gunes, Mustafa (Department of Urology, Faculty of Medicine, Yuzuncu Yil University) ;
  • Kaba, Mehmet (Urology Clinic, Van Training and Research Hospital) ;
  • Tanik, Serhat (Department of Urology, Faculty of Medicine, Bozok University) ;
  • Yuksel, Mehmet Bilgehan (Department of Urology, Faculty of Medicine, Celal Bayar University) ;
  • Arslan, Harun (Radiology Clinic, Van Training and Research Hospital) ;
  • Demir, Halit (Department of Chemistry, Faculty of Medicine, Yuzuncu Yil University)
  • Published : 2013.01.31

Abstract

Trace elements which are essential components of biological structures may also be toxic when present at levels above the amounts required for biological function. In our study, trace element levels were measured with furnace atomic absorption spectrophotometry in 33 newly diagnosed renal cell carcinoma cases (preoperative) and 32 healthy controls. When compared with the control group, it was found that the levels of cadmium (Cd), lead (Pb) were higher and the levels of zinc (Zn), iron (Fe) and manganese (Mn) were lower in the patient group. These changes may be important in the formation of renal cell carcinoma, a question which should be explored with postoperative comparative studies.

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