A study of contrast agent peak time using biomechanics factors experimental contrast medium infusion test using at contrast enhanced magnetic resonance angiography

조영증강검사 시 생체 요인을 이용한 조영제 peak time에 관한 연구

  • Son, Soon-Yong (Department of Health Science, Graduate School Hanyang University) ;
  • Kim, Yoon-Shin (Department of Health Science, Graduate School Hanyang University) ;
  • Choi, Kwan-Woo (Department of Radiology, Asan Medical Center) ;
  • Seo, Sung-Mi (Department of Radiology, Asan Medical Center) ;
  • Min, Jung-Whan (Department of Radiology, Shin-Gu University) ;
  • Yoo, Beong-Gyu (Department of Radiotechnology, Wonkwang Health Science University) ;
  • Lee, Jong-Seok (Department of Radiotechnology, Wonkwang Health Science University)
  • 손순룡 (한양대학교 대학원 보건학과) ;
  • 김윤신 (한양대학교 대학원 보건학과) ;
  • 최관우 (서울아산병원 영상의학과) ;
  • 서성미 (서울아산병원 영상의학과) ;
  • 민정환 (신구대학교 방사선과) ;
  • 유병규 (원광보건대학교 방사선과) ;
  • 이종석 (원광보건대학교 방사선과)
  • Received : 2012.11.16
  • Accepted : 2013.02.06
  • Published : 2013.02.28


In this study was explored minimize side effects due to the additional injection of contrast medium and maintaining a high resolution imaging applied to the inspection and analysis of the contrast medium that affect the peak time biomechanics factors. Included 48 patients using the test bolus method, after measuring a patient's biomechanics factors of inspection before and during the test, correlation between contrast medium peak time and learn, matches the regression equation calculated and measured contrast medium peak time was assessed by the Bland Altman plot. Research result, inspections of SBP, HR contrast medium peak time and a significant negative correlation was, step 1, every increase, the contrast medium peak time significantly to -0.018 and -0.159 decreased, a fairly high concordance no difference between the two method. In conclusion, the regression equation using the existing methods, while maintaining excellent image quality that contrast medium is reduced to a patient, it can conclude that the alternative to the existing methods.


Supported by : 원광보건대학교


  1. Korean Statistical Information Service. Death and daeth rates By cause [Ienternet], From: abroad_01List.jsp?parentid=D. (accessed Oct., 10, 2012)
  2. S. J. Bae, C. H. Lim, B. R. Park, W. J. Shin, J. S. Kim, "The Value of Comparison with Four Dimension Time Resolved Imaging of Contrast Kinetics(TRICKS) MRA by Time of Flight(TOF) MRA", J Magn Korean contents, 10, pp. 215-221, 2009. DOI:
  3. J. H. Choi, S. M. Lim, Y. Kim, "Comparison of 3D TOF MRA with Contrast Enhanced MRA in Intracranial Atherosclerotic Occlusive Disease", J Korean Radiol Soc, 64, pp. 203-211, 2011.
  4. Y. S. Ji, B. J. Lee, "Usefulness of 3-Dimensional Gadolinium-enjancde MR Angiography for the Evaluation of Pedal Artery: Comparison with digital subtraction angiography", J Korean Radiol Soc, 47, pp. 21-26, 2002.
  5. Y. H. Kim, "Usefulness of Magnetic Resonance Angiography in Intracranial Arteriovenous Malformation", J Korean Radiol Soc, 30, pp. 7-14, 1994.
  6. B. J. Park, M. G. Kim, S. I. Suh, S. J. Hong, K. R. Cho, B. K. Seo, K. Y. Lee, N. J. Lee, J. H. Kim, "The Usefulness of Test Bolus Examination in Three Dimensional Contrast Enhanced MR Angiography of the Carotid Artery", J Korean Med, 44, pp. 317-323, 2001.
  7. S. Y. Kim, Y. K. Kim, S. M. Yoon, K. H. Yoo, J. S. Lim, "Using Keyhole and SENSE Technique 4D (time-resolved) MRA", Korean Journal of Magn Reson technology, 18, pp. 244-252, 2005.
  8. Y. E. Chung, "Optimal delay time for the hepatic parenchymal enhancement at the multidetector CT examination", The Graduate School Yonsei Universit Department of Medicine, 1, pp. 1-50, 2006.
  9. Korean Society of Magnetic Resonance in Medicine, "magnetic resonance imaging", pp. 194-210, 316-326, Ilchokak, 2008.
  10. K. W. Chung, T. S. Chung, J. Y. Joo, "What is the Cause of Signal Inhomogeneity at the Carotid Bifurcation During Contrast Enhanced Carotid MRA? : In Vivo and in Vitro Studies", J Korean Radiol Soc, 30, pp. 7-14, 1994.
  11. J. P. Earls, "Breath-hold single-dose gadoliniym enhance three dimensional MR aortography: usefulness of a timing examination and MR power injection", Radiology, 201, pp. 705-710, 1996.
  12. M. K. Kim, Y. W. Oh, K. H. Shin, K. B. Chung, W. H. Suh, "Assessment of Contrast enhanced 3D Ultrafast Pulmonary MR Angiography Using Test Injection: Comparison between Single Dose and Double Dose", J Korean Radiol Soc, 41, pp.73-78, 1999.

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