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Reasons for Variation in Sensitivity and Specificity of Visual Inspection with Acetic Acid (VIA) for the Detection of Pre-Cancer and Cancer Lesions of Uterine Cervix

  • Parashari, Aditya (Division of Clinical Research, Institute of Cytology and Preventive Oncology (ICMR)) ;
  • Singh, Veena (Division of Clinical Research, Institute of Cytology and Preventive Oncology (ICMR))
  • Published : 2013.12.31

Abstract

Alternative strategies such as visual inspection of cervix with acetic acid, are real time, economical and easily implemented methods for cervical cancer screening. However, variable sensitivity and specificity have been observed in various community based studies. The possible reasons could include variation in man power training, light source used for visualization, and preparation of diluted (4-5%) acetic acid and its storage. A standardized protocol for training, teaching material (easy to understand in the local language) for trainees, supervision and reinforcement by intermittent and supplementary training to check the quality of their observation, a standard protocol for preparation dilute acetic acid and its storage and a standard good light source (equivalent to day light) are needed to minimize the variation in sensitivity and specificity of VIA in community settings.

References

  1. Fei HL, Cheng YF, Cheng XD, et al (2011). Evaluation of five screening methods for an early detection of cervical cancer and its precancerous lesions in Zhejiang province. Zhonghua Yi Xue. 91, 309-12.
  2. Parashari Aditya, Singh V, Sehgal A, et al (20000. Low-cost technology for screening uterine cervical cancer. Bull WHO. 78, 964-7.
  3. Sankarnarayanan R, Nessa A, Esmy PO, et al (2012). Visual inspection methods for cervical cancer prevention. Best Pract Res Clin Obstet Gynaecol, 26, 221-32. https://doi.org/10.1016/j.bpobgyn.2011.08.003
  4. Sangwa-Lugoma G, Mahmud S, Nasr SH, et al (2006). Visual inspection as a cervical cancer screening method in a primary health care setting in Africa. Int J Cancer, 119, 1389-95. https://doi.org/10.1002/ijc.21972
  5. Sherigar B, Dalal A, Durdi G, et al (2010). Cervical cancer screening by visual Inspection with acetic acid - interobserver variability between nurse and physician. Asian Pac J Cancer Prev, 11, 619-22.
  6. Singh V, Parashari A, Sehgal A (2012). Man power training for early cervical cancer detection. Acta Obstet Gynecol Scand, 91, 1124-7. https://doi.org/10.1111/j.1600-0412.2012.01449.x
  7. Singh V, Parashari A, Sehgal A (2013). VIA screening for cervical cancer in developing countries: Potential role of the light source. J Obstet Gynaecol, 33, 898-99. https://doi.org/10.3109/01443615.2013.823389

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  6. Needs for Professional Education to Optimize Cervical Cancer Screenings in Low-Income Countries: a Case Study from Tanzania pp.1543-0154, 2017, https://doi.org/10.1007/s13187-017-1276-6
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