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Cabbage (Brassica oleracea L. var. capitata) Phytochemicals with Antioxidant and Anti-inflammatory Potential

  • Rokayya, Sami ;
  • Li, Chun-Juan ;
  • Zhao, Yan ;
  • Li, Ying ;
  • Sun, Chang-Hao
  • Published : 2013.11.30

Abstract

Background: The objective of this study was to investigate antioxidant and anti-inflammatory activity of cabbage phytochemicals. Materials and Methods: Color coordinates were evaluated by colorimetry, and the antioxidant and anti-inflammatory activities were analyzed by spectrophotometer for some common cabbage varieties. Results: Red heads had the highest total antioxidant contents followed by Savoy, Chinese and green heads. The Chinese variety had the highest ABTS (2,2-azino-di-(3-ethylbenzthiazoline-sulfonic acid) antioxidant activity, was 5.72 ${\mu}mol$ TE/g fw (Trolox equivalent). The green variety had the highest DPPH (free radical scavenging activity) antioxidant activity, which was 91.2 ${\mu}mol$ TE/g fw. The red variety had the highest FRAP (ferric reducing antioxidant power) antioxidant activity, which was 80.8 ${\mu}mol$ TE/g fw. The total phenol amounts were 17.2-32.6 mM trolox equivalent antioxidant capacity (TEAC) and the total flavonoid amounts were 40.0-74.2 mg quercetin per gram. Methanolic extracts of different cabbage heads showed different anti-inflammatory activity values. Chinese, Savoy and green heads had the highest anti-inflammatory activity, while red heads had the lowest. Conclusions: The results suggest that these varieties of cabbage heads could contribute as sources of important antioxidant and anti-inflammatory related to the prevention of chronic diseases associated to oxidative stress, such as in cancer and coronary artery disease.

Keywords

Cabbage head;antioxidant;anti-inflammatory;cell

References

  1. Brand-Williams B, Cuvelier ME, Berset C (1995). Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci Tech, 28, 25-30. https://doi.org/10.1016/S0023-6438(95)80008-5
  2. Cheney G (1949). Rapid healing of peptic ulcers in patients receiving fresh cabbage juice. California Med, 70, 10-5.
  3. Chiplonkar SA, Tarwadi KV, Kavedia RB, et al (1999). Fortication of vegetarian diets for increasing bioavailable iron density using green leafy vegetables. Food Res Int, 32, 169-74. https://doi.org/10.1016/S0963-9969(99)00070-8
  4. Dumas Y, Dadomo M, Di Lucca G, et al (2003). Effects of environmental factors and agricultural techniques on antioxidant content of tomatoes. J Sci Food Agric, 83, 369-82. https://doi.org/10.1002/jsfa.1370
  5. Evans DA, Hirsch JB, Dushenkov S (2006). Phenolics, inflammation and nutrigenomics. J Sci Food Agric, 86, 2503-9. https://doi.org/10.1002/jsfa.2702
  6. Hart DJ, Scott KJ (1995). Development and evaluation of an HPLC method for the analysis of carotenoids in foods, and the measurement of the carotenoids content of vegetables and fruits commonly consumed in the UK. Food Chem, 54, 101-11. https://doi.org/10.1016/0308-8146(95)92669-B
  7. Hernandez-Ortega M, Ortiz-Moreno A, Hernandez-Navarro MD, et al (2012). Antioxidant, antinociceptive, and anti-Inflammatory effects of carotenoids extracted from dried pepper (Capsicum annuum L.). J Biomed Biotech, ID 524019, 10 pages
  8. Ilahy R, Hdider C, Lenucci MS, et al (2011). Antioxidant activity and bioactive compound changes during fruit ripening of high-lycopene tomato cultivars. J Food Compos Anal, 24, 588-95. https://doi.org/10.1016/j.jfca.2010.11.003
  9. Jordbruksverket (2003). Consumption of foodstuffs. Year book of agricultural statistics. Orebro, Sweden: SCB-Tryck, 2003, 259-72.
  10. Joseph B, Raj SJ (2010). Phytopharmacological properties of Ficcus racemosa Linn: An overview. Int J Pharm Sci Rev Res, 3, 134-8.
  11. Kaur C, Walia S, Nagal S, et al (2013). Functional quality and antioxidant composition of selected tomato (Solanum lycopersicon L) cultivars grown in Northern India. LWT-Food Sci Tech, 50, 139-45. https://doi.org/10.1016/j.lwt.2012.06.013
  12. Kusznierewicz B, Bartoszek A, Wolska L, et al (2008). Partial characterization of white cabbages (Brassica oleracea var. capitata f. alba) from different regions by glucosinolates, bioactive compounds, total antioxidant activities and proteins. LWT . Food Sci Tech, 41, 1-9. https://doi.org/10.1016/j.lwt.2007.02.007
  13. Lee J, Murakami A, Watanabe S, et al (2009). Suppressive properties of extracts from Japanese Edible Plants regarding nitric oxide generation. Asian Pac J Cancer Prev, 10, 263-72.
  14. Liu D, Shi J, Ibarra AC, et al (2008). The scavenging capacity and synergistic effects of lycopene, vitamin E, vitamin C, and b-carotene mixtures on the DPPH free radical. LWT - Food Sci Tech, 41, 1344-9. https://doi.org/10.1016/j.lwt.2007.08.001
  15. Magalhaes LM, Segundo MA, Reis S, et al (2008). Methodological aspects about in vitro evaluation of antioxidant properties. Anal Chim Acta, 613, 1-19. https://doi.org/10.1016/j.aca.2008.02.047
  16. Maritess C, Small S, Waltz-Hill M (2005). Alternative nutrition therapies in cancer patients. Sem Oncol Nurs, 21, 173-6. https://doi.org/10.1016/j.soncn.2005.04.005
  17. Murakami A, Ishida H, Kubo K, et al (2005). Suppressive effects of Okinawan Food Items on free radical generation from stimulated leukocytes and identification of some active constituents: implications for the prevention of inflammation-associated carcinogenesis. Asian Pac J Cancer Prev, 6, 437-48.
  18. Nilsson J, Olsson K, Engqvist G, et al (2006). Variation in the content of glucosinolates, hydroxycinnamic acids, carotenoids, total antioxidant capacity and low-molecular-weight carbohydrates in Brassica vegetables. J Sci Food Agric, 86, 528-38. https://doi.org/10.1002/jsfa.2355
  19. Penas E, Martinez-Villaluenga C, Frias J, San et al (2012). Se improves indole glucosinolate hydrolysis products content, se-methylselenocysteine content, antioxidant capacity and potential anti-inflammatory properties of sauerkraut. Food Chem, 132, 907-14. https://doi.org/10.1016/j.foodchem.2011.11.064
  20. Prasad N, Yang B, Kong KW, et al (2013). Phytochemicals and Antioxidant Capacity from Nypa fruticans Wurmb. Fruit. Evid Based Complement Alternat Med, 2013, 154606.
  21. Raghu KL, Ramesh CK, Srinivasa TR, et al (2011). Total antioxidant capacity in aqueous extracts of some common vegetables. Asian J Exp Biol, 2, 58-62.
  22. Re R, Pellegrini N, Proteggente A, et al (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Rad Bioand Med, 26, 1231-7. https://doi.org/10.1016/S0891-5849(98)00315-3
  23. Samec D, Piljac-Zegarac J, Bogovi M, et al (2011). Antioxidant potency of white (Brassica oleracea L. var. capitata) and Chinese (Brassica rapa L. var. pekinensis (Lour.)) cabbage: The influence of development stage, cultivar choice and seed selection. Sci Hort, 128, 78-83. https://doi.org/10.1016/j.scienta.2011.01.009
  24. Singh J, Upadhyay AK, Bahadur A, et al (2006). Antioxidant phytochemicals in cabbage (Brassica oleracea L. var. capitata). Sci Hort, 108, 233-7. https://doi.org/10.1016/j.scienta.2006.01.017
  25. Sladowski D, Steer SJ, Clothier RH, et al (1993). An improved MTT assay. J Immunol Methods, 157, 203-7. https://doi.org/10.1016/0022-1759(93)90088-O
  26. Suido H, Tanaka T, Tabei T, et al (2002). Mixed green vegetable and fruit beverage decreased the serum level of low-density lipoprotein cholesterol in hypercholesterolemic patients. J Agric Food Chem, 50, 3346-50. https://doi.org/10.1021/jf0116698
  27. Wennberg M, Ekvall J, Olsson K, et al (2006). Changes in carbohydrate and glucosinolate composition in white cabbage (Brassica oleracea var. capitata) during blanching and treatment with acetic acid. Food Chem, 95, 226-36. https://doi.org/10.1016/j.foodchem.2004.11.057
  28. Yen WJ, Change LW, Duh PD (2005). Antioxidant activities of peanut seed test and its antioxidative component. Ethyl protocatechuate. Leb-Wiss Technol, 38, 193-200. https://doi.org/10.1016/j.lwt.2004.06.004
  29. Zanfini A, Corbini G, La Rosa C, et al (2010). Antioxidant activity of tomato lipophilic extracts and interactions between carotenoids and atocopherol in synthetic mixtures. LWT - Food Sci Tech, 43, 67-72. https://doi.org/10.1016/j.lwt.2009.06.011

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