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Magnetic Resonance Image Manifestations of the Atypical Meningioma

  • Wu, Qing-Wu (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Yan, Rui-Fang (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Li, Qiang (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Hu, Ying (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Zhou, Feng-Mei (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Ren, Ji-Peng (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Yang, Rui-Min (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University) ;
  • Zhang, Yan (Department of Medical Imaging, the First Affiliated Hospital of Xinxiang Medical University)
  • Published : 2013.11.30

Abstract

Through retrospective analysis of 13 cases of magnetic resonance image (MRI) manifestations of atypical meningiomas confirmed by operation and pathology in the First Affiliated Hospital of Xinxiang Medical University, the objective of this study was to evaluate the diagnostic value of MRI in order to improve the accuracy rate of preoperative diagnosis. In this retrospective analysis of MRI findings for atypical meningiomas in First Affiliated Hospital of Xinxiang Medical University from January to July in 2012, the location, morphology and tumor signals and other tumor imaging characteristics were covered. In 13 cases of atypical meningioma patients of this group, most tumors were located at typical sites (10/13), mainly the falx cerebri, parasagittal, convexity, saddle area. Only two cases were at atypical locations, 1 in the cerebellar hemisphere and 1 in a lateral ventricle. Most of the tumors showed T1 and T2 isointensity signals, and necrosis, calcification, and peritumoral edema were always featured. DWI showed isointensity in 11 cases (11/13), and hyperintensity in 2. Some 9 cases had dural tail signs, 12 had accurate positioning (12/13), and 2 were postoperative recurrences. MRI has high value in the diagnosis of atypical meningiomas, with important roles in early clinical diagnosis, treatment and prognosis evaluation.

Keywords

Atypical meningioma;magnetic resonance imaging;pathology;clinical features

References

  1. Alvarez F, Roda JM, Perez Romero M, et al (1987). Malignant and atypical meningionmas: a reappraisal of clinical, hostological, and computed tomographic features. Neurosurgery, 20, 688-94. https://doi.org/10.1227/00006123-198705000-00003
  2. Boss A, Bisdas S, Kolb A, et al (2010). Hybrid PET/MRI of intracranial masses: initial experiences and comparison to PET/CT. J Nucl Med, 51, 1198-205. https://doi.org/10.2967/jnumed.110.074773
  3. Chiu SH, Wang ID, Sytwu HK, Hueng DY (2013). Atypical meningioma. J Neurosurg, 4,912-3.
  4. Filippi CG, Edgar MA, Ulu. AM, et al (2001). Appearance of menigiomas on diffusion weighted images: correlating diffusion constants with histopathologic findings. AJNR Am J Neuroradiol, 22, 65-72.
  5. Hakyemez B, Erdogan C, Oruc E, et al (2007). Foramen of Monro meningioma with atypical appearance: CT and conventional MR findings. Australas Radiol, 51, B3-5. https://doi.org/10.1111/j.1440-1673.2007.01784.x
  6. Hsu CC, Pai CY, Kao HW, et al (2010). Do aggressive imaging features correlate with advanced histopathological grade in meningiomas? J Clin Neurosci, 17, 584-7. https://doi.org/10.1016/j.jocn.2009.09.018
  7. Kane AJ, Sughrue ME, Rutkowski MJ, et al (2011). Anatomic location is a risk factor for atypical and malignant meningiomas.Cancer,6,1272-8.
  8. Kim EY, Kim ST, Kim HJ, et al (2009). Intraventricular meningiomas: radiological findings and clinical features in 12 patients. Clin Imaging, 33, 175-80. https://doi.org/10.1016/j.clinimag.2008.09.005
  9. Kleihuse P, Louis DN, Scheithauer BW, et al (2002). The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol, 61, 215-25. https://doi.org/10.1093/jnen/61.3.215
  10. Lakshmi M, Glastonbury CM (2009). Imaging of the cerebellopontine angle. Neuroimaging Clin N Am, 19, 393-406. https://doi.org/10.1016/j.nic.2009.06.004
  11. Lin CK, Tsai WC, Lin YC, Hueng DY (2012). Osteopontin predicts the behavior of atypical meningioma. Histopathology, 60, 320-5. https://doi.org/10.1111/j.1365-2559.2011.04085.x
  12. Louis DN, Ohgaki H, Wiestler OD, et al (2007). The 2007 WHO classification of tumors of the central nervous system. Acta Neuropathol, 114, 97-109. https://doi.org/10.1007/s00401-007-0243-4
  13. Matsushima N, Maeda M, Takamura M, et al (2007). MRI findings of atypical meningioma with microcystic changes. J Neurooncol, 82, 319-21. https://doi.org/10.1007/s11060-006-9285-z
  14. Matttei TA, Mattei JA, Ramina R, et al (2005). Edema and malignancy in meningiomas. Clinics (Sao Paulo), 60, 201-6. https://doi.org/10.1590/S1807-59322005000300004
  15. Mogi A, Hirato J, Kosaka T, Yamaki E, Kuwano H (2012). Primary mediastinal atypical meningioma: report of a case and literature review. World J Surg Oncol, 10, 17. https://doi.org/10.1186/1477-7819-10-17
  16. Pharham DM, Weeks DA, Bechwith JB (1994). The clinicopathologic spectrum of putative extearenal rhaboid tumora, an analysis of 42 cases studied with immunuohistochemistry or electron microscopy. Am J Surg Pathol, 18, 1010-29. https://doi.org/10.1097/00000478-199410000-00005
  17. Rieken S, Habermehl D, Haberer T, et al (2012). Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts. Radiat Oncol, 7, 41. https://doi.org/10.1186/1748-717X-7-41
  18. Sameh AS, Mostafa S (2011). Atypical meningioma: Clinicopathological analysis of a new WHO classification. Pan Arab J Neurosurg, 1, 36-41.
  19. Smith HP, Challa VR, Moody DM, Kelly DL Jr (1981). Biological features of meningiomas that determine the production of cerebral edema. Neurosurgery, 8, 428-33. https://doi.org/10.1227/00006123-198104000-00004
  20. Sriram PR (2013). Chordoid meningioma, part of a multiple intracranial meningioma: a case report & review. Malays J Med Sci, 4, 91-4.
  21. Tomura N, Takahashi S, Sakuma I, et al (2004). Neuroradiological findings of atypical meningiomas. Comput Med Imag Grap, 28, 33-9. https://doi.org/10.1016/j.compmedimag.2003.09.003
  22. Veillon F, Taboada LR, Eid MA, et al (2008). Pathology of the facial nerve. Neuroimaging Clin N Am, 18, 309-20. https://doi.org/10.1016/j.nic.2008.01.002
  23. Whillte IR, Smith C, Navoo P, Collie D (2004). Meningiomas. Lancet, 363, 1535-43. https://doi.org/10.1016/S0140-6736(04)16153-9
  24. Zaher A, Bari Mattar MA, Zayed DH, Ellatif RA, Ashamallah SA (2013). Atypical meningioma: a study of prognostic factors. World Neurosurg, Jul 16. [Epub ahead of print]
  25. Zhang BY, Yin B, Li YX, et al (2012). Neuroradiological findings and clinical features of fourth-ventricular meningioma: a study of 10 cases. Clin Radiol, 67, 455-60. https://doi.org/10.1016/j.crad.2011.10.017

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