Incidence, Survival and Prevalence of Esophageal and Gastric Cancer in Linzhou City from 2003 to 2009

  • Liu, Shu-Zheng (Department of Epidemiology, College of Public Health of Zhengzhou University) ;
  • Wang, Bing (Department of Internal Neurology, Henan Provincial People's Hospital) ;
  • Zhang, Fang (The Human Resource Department, the First Affiliated Hospital of Henan University of TCM) ;
  • Chen, Qiong (Henan Cancer Research and Control Office, Henan Cancer Hospital) ;
  • Yu, Liang (Linzhou Cancer Registry, Linzhou Cancer Hospital) ;
  • Cheng, Lan-Ping (Linzhou Cancer Registry, Linzhou Cancer Hospital) ;
  • Sun, Xi-Bin (Henan Cancer Research and Control Office, Henan Cancer Hospital) ;
  • Duan, Guang-Cai (Department of Epidemiology, College of Public Health of Zhengzhou University)
  • Published : 2013.10.30


This study describes recent trends in incidence, survival and prevalence of subgroups of esophageal and gastric cancer in Linzhou city between 2003 and 2009. Data of esophageal and gastric cancer for the period of interest were extracted from the Linzhou Cancer Registry. Using information on tumor morphology or anatomical site, data were divided into six groups; esophageal squamous cell carcinoma, esophageal adenocarcinoma, other and unspecified types of esophageal cancer, and cardia, non-cardia, and unspecified anatomical site of stomach cancer. Incidence, survival and prevalence rates for each of the six cancer groups were calculated. The majority of esophageal cancers were squamous cell carcinomas (82%). Cardiac cancer was the major gastric cancer group (64%). The incidence of esophageal squamous cell carcinoma and gastric cardiac cancer increased between 2003 and 2009. Both esophageal and gastric cancer had a higher incidence in males compared with females. Overall survival was poor in all sub-groups with 1 year survival ranging from 45.9 to 65.6% and 5 year survival ranging from 14.7 to 30.5%. Prevalence of esophageal squamous cell carcinoma and gastric cardiac cancer was high (accounting for 80% overall). An increased focus on prevention and early diagnosis, especially in esophageal squamous cell carcinoma and gastric cardiac cancer, is required.


Esophageal cancer;gastric cancer;incidence;prevalence;survival;linzhou


  1. Fan YJ, Song X, et al (2008). Esophageal and gastric cardia cancers on 4238 Chinese patients residing in municipal and rural regions: a histopathological comparison during 24-year period. World J Surg, 32, 1980-8.
  2. Brenner H, Rothenbacher D, et al (2009). Epidemiology of stomach cancer. Methods Mol Biol, 472, 467-77.
  3. Coupland VH, Allum W, et al (2012). Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study. BMC Cancer, 12, 11.
  4. Hansson LE, Sparen P, et al (1993). Increasing incidence of carcinoma of the gastric cardia in Sweden from 1970 to 1985. Br J Surg, 80, 374-7.
  5. He YT, Hou J, et al (2008). Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China. Eur J Cancer Prev, 17, 71-6.
  6. Hur C, Miller M, et al (2013). Trends in esophageal adenocarcinoma incidence and mortality. Cancer, 119, 1149-58.
  7. Ji BT, Chow WH, et al (1997). Body mass index and the risk of cancers of the gastric cardia and distal stomach in Shanghai, China. Cancer Epidemiol Biomarkers Prev, 6, 481-5.
  8. Jie HPZ, Chen W (2012). Chinese cancer registry annual report. Military medical science press, Beijing.
  9. Kamangar F, Chow WH, et al (2009). Environmental causes of esophageal cancer. Gastroenterol Clin North Am, 38, 27-57.
  10. Lagergren J, Lagergren P (2010). Oesophageal cancer. BMJ, 341, 6280.
  11. Liu SZ, Zhang F, et al (2013). Prediction of temporal trends in gastric cancer mortality in Linzhou city from 1988 to 2010. Zhonghua Yu Fang Yi Xue Za Zhi, 47, 113-7.
  12. Liu SZ, Zhang F, et al (2012). Time trends of esophageal cancer mortality in Linzhou city during the period 1988-2010 and a Bayesian approach projection for 2020. Asian Pac J Cancer Prev, 13, 4501-4.
  13. Sun XB, Liu ZC, et al (2007). Descriptive analysis of incidence and time trends of esophageal and gastric cancers in Linzhou city. Zhonghua Zhong Liu Za Zhi, 29, 764-7.
  14. Thrift AP, Whiteman DC (2012). The incidence of esophageal adenocarcinoma continues to rise: analysis of period and birth cohort effects on recent trends. Ann Oncol, 23, 3155-62.
  15. Wang JB, Fan JH, et al (2012). Attributable causes of esophageal cancer incidence and mortality in China. PLoS One, 7, 42281.
  16. Xibib S, Meilan H, et al (2003). Risk factors for oesophageal cancer in Linzhou, China: a case-control study. Asian Pac J Cancer Prev, 4, 119-24.
  17. Xibin S, Moller H, et al (2002). Residential Environment, Diet and Risk of Stomach Cancer: a Case-control Study in Linzhou, China. Asian Pac J Cancer Prev, 3, 167-72.

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