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Herbal Remedies for Combating Irradiation: a Green Anti-irradiation Approach

  • Lachumy, Subramanion Jothy (Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia) ;
  • Oon, Chern Ein (Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia) ;
  • Deivanai, Subramanian (Department of Biotechnology, Faculty of Applied Sciences, AIMST University) ;
  • Saravanan, Dharmaraj (Faculty of Medicine and Health Sciences, University Sultan Zainal Abidin) ;
  • Vijayarathna, Soundararajan (Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia) ;
  • Choong, Yee Siew (Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia) ;
  • Yeng, Chen (Dental Research and Training Unit, and Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya) ;
  • Latha, Lachimanan Yoga (Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia) ;
  • Sasidharan, Sreenivasan (Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia)
  • Published : 2013.10.30

Abstract

Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane. Plants also play a major role in our nutrition by converting energy from the sun during photosynthesis. In addition, plants have been used extensively in traditional medicine since time immemorial. Information in the biomedical literature has indicated that many natural herbs have been investigated for their efficacy against lethal irradiation. Pharmacological studies by various groups of investigators have shown that natural herbs possess significant radioprotective activity. In view of the immense medicinal importance of natural product based radioprotective agents, this review aims at compiling all currently available information on radioprotective agents from medicinal plants and herbs, especially the evaluation methods and mechanisms of action. In this review we particularly emphasize on ethnomedicinal uses, botany, phytochemistry, mechanisms of action and toxicology. We also describe modern techniques for evaluating herbal samples as radioprotective agents. The usage of herbal remedies for combating lethal irradiation is a green anti-irradiation approach for the betterment of human beings without high cost, side effects and toxicity.

Keywords

Medicinal plant;ionizing radiation;radioprotective;green approach

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