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Antioxidant Activity and Effects on Brain Tissues After Administering Kudzu Leaf Extract on Rats with Induced Stress Due to Laryngeal Injury

후두 손상으로 스트레스 유발시킨 랫드에 칡잎추출물을 투여 후 항산화작용과 뇌 조직에 미치는 영향

  • Received : 2013.08.21
  • Accepted : 2013.12.05
  • Published : 2013.12.31

Abstract

To examine the effects of voice disorders after a laryngeal injuryon the changes in stress, this study examined the effects of the changes observed in laboratory animals and on stress reduction effects, by inducing a laryngeal injury in SD type rats after administering a kudzu leaf extract, which has a sedation effect. For testing, a total of 24 rats comprising the normal group, control group and experimental groups (1 and 2 6 rats in each group) were used, and antioxidant experiments and molecular and chemical tests were conducted by administering a specified amount of kudzu teaorally once a day at a set time, 6 times per week for 5 weeks. The control group appeared to be significantly higher than the normal group (p <0.05), whereas the experimental group showed significant decreases compared to the control group (p <0.05), showing a better result than the normal group. The test results showed that the kudzu leaf extract resulted in significant changes compared to the control group. Overall, the administration of kudzu leaf extract has stress reduction effects.

Keywords

anti-oxidant;Kudzu;laryngeal;molecular;stress

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