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The Effect of Red Ginseng Extracts on Blood Biochemical Parameters, Bone Density and Bone Inorganic Components in Ovariectomized Rats

홍삼추출물이 난소절제 흰쥐의 혈액 생화학적 지표, 골 밀도 및 골무기질에 미치는 영향

  • Kim, Byung-Weon (Dept. of Biomedical Laboratory Science, Gimcheon University) ;
  • Lee, Yoon-Bok (Dept. of Central Research Institute, Chung's Food Co. LTD.) ;
  • Park, Jae-Seung (Dept. of Biomedical Laboratory Science, Sohae University) ;
  • Park, Ji-Won (Dept. of Medical Management, Gimcheon University) ;
  • Hwang, Seock-Yeon (Dept. of Biomedical Laboratory Science, Daejeon University)
  • 김병원 (김천대학교 임상병리학과) ;
  • 이윤복 ((주)정식품 중앙연구소) ;
  • 박재승 (서해대학교 임상병리과) ;
  • 박지원 (김천대학교 의료경영학과) ;
  • 황석연 (대전대학교 임상병리학과)
  • Received : 2013.07.21
  • Accepted : 2013.10.20
  • Published : 2013.10.28

Abstract

We investigated the effect of red ginseng extracts on blood biochemical parameters, bone density and bone inorganic components etc. and data were analyzed by one-way ANOVA and Post-Hoc Test. In the results of our study, the level of albumin and HDL, Ca, P, Mg, and estradiol in blood, and the content of Ca, P, ash in femur were significantly increased in red ginseng treated group than in OVX group, and the level of ALP, AST, ALT, blood glucose, total cholesterol, triglyceride, LDL, creatinine, osteocalcin, and N-terminal telopeptide were significantly decreased in red ginseng treated group than in OVX group (p < 0.01). From these results, we knew that within the normal level, red ginseng extracts improved liver and kidney function, component of glucose and lipid in blood, bone density, bone ash and inorganic components in femur, and index related with bone metabolism.

Keywords

Red ginseng extracts;Blood biochemical components;Blood glucose;Bone density;Bone inorganic components

Acknowledgement

Supported by : 농림수산식품부