- Volume 13 Issue 6
DOI QR Code
Human Papillomavirus Screening in North Indian Women
- Pandey, Saumya (Krishna Medical Center, Chhatrapati Shahuji Maharaj Medical University) ;
- Mishra, Malvika (Krishna Medical Center, Chhatrapati Shahuji Maharaj Medical University) ;
- Chandrawati, Chandrawati (Krishna Medical Center, Chhatrapati Shahuji Maharaj Medical University)
- Published : 2012.06.30
Objectives: Human papillomavirus (HPV) is the major etiological agent of cervical cancer, a leading cause of morbidity and mortality in women worldwide. Screening strategies for reducing the burden of HPV-mediated carcinogenesis are emerging as an effective means for cervical cancer control and prevention in developing countries. Our study, therefore, aimed to identify HPV infection status in North Indian women during random population screening. Methodology: Cervical/vaginal exfoliated cells and/or Pap smear specimens were collected from 890 women of North Indian ethnicity residing in Lucknow and adjoining areas, during random population screening from June 2009-March 2012. HPV viral loads in clinical specimens were determined by the Hybrid Capture (hc)-2 HPV DNA assay, and subsequently, positive/negative/borderline HPV status was calculated. Results: The HPV incidence in the present study was 11.7%. 751 out of a total of 890 women (84.4%) participating in our HPV screening program were HPV negative (HPV -), 104 (11.7%) tested positive (HPV +) while 35 (3.9%) showed borderline (HPV
Cervical cancer;human papillomavirus;north India;screening;viral load
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