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Phylogenetic Analysis of Korean Native Goats Based on the Mitochondrial Cytochrome b Gene

mtDNA Cytochrome b 유전자에 기초한 한국재래염소의 계통유전학적 분석

  • 김재환 (농촌진흥청 국립축산과학원) ;
  • 변미정 (농촌진흥청 국립축산과학원) ;
  • 고응규 (농촌진흥청 국립축산과학원) ;
  • 김성우 (농촌진흥청 국립축산과학원) ;
  • 김상우 (농촌진흥청 국립축산과학원) ;
  • 도윤정 (농촌진흥청 국립축산과학원) ;
  • 김명직 (농촌진흥청 국립축산과학원) ;
  • 윤세형 (농촌진흥청 국립축산과학원) ;
  • 최성복 (농촌진흥청 국립축산과학원)
  • Received : 2012.04.10
  • Accepted : 2012.05.24
  • Published : 2012.08.31

Abstract

The goal of this study was to verify the phylogenetic status of the Korean native goats (KNG). We determined the complete sequence of the mitochondrial cytochrome b gene in 48 goats among four populations. We also analyzed genetic variability within goats, and a phylogenetic analysis was performed by comparison with other country's goats. Three nucleotide substitutions were detected, and two of these were missense mutations that occurred due to a substitution of amino acid. Four haplotypes were defined from KNG. Three of these haplotypes were only found in the Chinese goat. However, the other haplotype was KNG-specific. In the phylogenetic analysis, four clades (A~D) were classified among domestic goats, and the KNG was classified into clade 1 that estimated as lineage A based on the D-loop sequence. Each haplotype from the KNG was clustered closely with that of the Chinese goat. The results of haplotype distribution and phylogenetic location suggest that strong gene flow occurred from China to the Korean Peninsula.

Keywords

Korean native goat;Phylogenetic analysis;Cytochrome b;Haplotype;Gene flow

Acknowledgement

Supported by : 농촌진흥청

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