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The Effect of glutathione contents of White Ginseng(WG) Extracts and Entomopathogenic Fugi Extracts on the liver in Mice that was irradiated by radiation

동충하초 추출물과 백삼추출물 투여가 방사선을 조사한 생쥐 간에서의 glutathione함량에 미치는 영향

  • Received : 2012.01.01
  • Accepted : 2012.04.24
  • Published : 2012.04.30

Abstract

The radioprotective effects of white ginseng and Entomopathogenic Fugi Extract on liver damage induced by X-ray were investigated. To one group of ICR male mice were given white ginseng(150 mg/kg/day for 7days, orally) and Entomopathogenic Fugi (200 mg/kg/day for 7days, orally) before X-ray irradiation. To another group were irradiated by 5 Gy(1.01 Gy/min) dose of X-ray. Contrast group were given with saline(0.1 ml). The levels of reduced(GSH) and oxidized(GSSG) glutathione in liver tissue were measured. The ratio of GSSG/total GSH was significantly decreased in the white ginseng and Entomopathogenic Fugi (200 mg/kg/day)(150 mg/kg/day) groups than irradiation group.

Keywords

X-ray;GSH;GSSG;Entomopathogenic Fugi;white ginseng;EF+Rad

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