Breast Cancer Scenario in a Regional Cancer Centre in Eastern India over Eight Years - Still a Major Public Health Problem

  • Published : 2012.03.31


In spite of screening and early diagnostic tests, the upward trend of breast cancer has become a matter of great concern in both developed and developing countries. The data collected by Population Based Cancer Registry in Chittaranjan National Cancer Institute, a regional cancer centre in Kolkata, from 1997 to 2004 gives an insight about the scenario of Breast Cancer in this part of Eastern India.The total no of female breast cancer cases were steadily increasing from 1997 to 2001 and only slightly lower from 2002 to 2004. and majority were in the 40-49 year old age group during this period. The next most commonly affected age group was 50-59 years. Regarding the distribution according to treatment, the main modality was surgery and radiotherapy followed by combined surgery, chemotherapy and radiotherapy and then combined surgery and chemotherapy. The commonest type was ductal followed by lobular cancer. In this eight year study in CNCI, status of patients on last day of the respective year was assessed. Number of patients alive was 43.5% in 1997. The percentage gradually increased up to 2000 and then gradually decreased to 47.4% in 2004. Also with every passing year, percentage mortality gradually decreased from 25.7% in 1997 to 16.8% in 2004. Better pattern of care (diagnosis and treatment) was reflected in this picture. However, lost to follow up, which also implies non compliance to treatment, increased to 30.8% in 1997 to 35.8% in 2004. Due to the small number of male breast cancers, only female cases were considered. In conclusion, breast cancer continues to be a major problem in Kolkata, India.


  1. Albrektse G, Heuch I, Thoresen SO (2010). Histological type and grade of breast cancer tumors by parity, age at birth, and time since birth a register-based study in Norway. BMC Cancer, 10, 226.
  2. Chintamani B, Murthy NS (2005). Clinico-morphological patterns of breast cancer including family history in a New Delhi hospital, India-A cross-sectional study. J Clin Oncol, 19, 106-11.
  3. Chopra R (2001). The Indian scene. J Clin Oncol, 19, 106-11.
  4. Chu KC, Tarone RE, Kessler LG, et al (1996). Recent trends in U.S. breast cancer incidence, survival, and mortality rates. J Natl Cancer Inst, 88, 1571-9.
  5. Dhar M, Lahiri S, Takiar R, Ashok NC, Murthy NS (2008). An indirect study of cancer survival in the context of developing countries. Asian Pac J Cancer Prev, 9, 479-86.
  6. Ferlay J, Bray F, Pisani P, Parkin DM: GLOBOCAN cancer cases in developing nations TNN Sep 15, 2011, 02.20am IST World Health Organization|The Lancet4(National Cancer Registry Programme.Time Trends in Cancer Incidence Rates 1982-2005.Indian Council of Medical Research.
  7. Forbes JF (1997). The incidence of breast cancer: the global burden, public health considerations. Sem Oncol, 24, 1-35.
  8. Gajalakshmi CK, Shanta V, Swaminathan R, Sankarnarayanan R, Black RJ (1997). A population-based survival study on female breast cancer in Madras, India. Br J Cancer, 75, 771-5.
  9. Henderson BE, Ross R, Bernstein L (1988). Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res, 48, 246-53
  10. Jamal A, Bray F, Melissa M, et al (2011). Global cancer statistics. Ca Cancer J Clin, 69-90
  11. Jussawalla DJ, Yeale BB, Natekar MV (1981). Histological and epidemiological features of breast cancer in different religious groups in greater Bombay. J Surg Oncol, 18, 269-79.
  12. Louwman WJ, Voogd Ac, Van Dijck JA, et al (2012). On the rising trends of incidence and prognosis for breast cancer patients diagnosed 1975-2004: a long-term population-based study in south-eastern Netherlands. Eindhoven Cancer Registry, Comprehensive Cancer Centre South (IKZ), Eindhoven, The Netherlands.
  13. Moolgavkar SH, Stevens RG, Lee JA (1979). Effect of age on incidence of breast cancer in females. J Natl Cancer Inst, 62, 493-501.
  14. Murthy NS, Chaudhry K, Nadayil D, Agarwal UK, Saxena S (2011). Changing trends in incidence of breast cancer:Indian scenario. Indian J Cancer, 20, 73-4209.
  15. Nandakumar A, Anantha N, Venugopal TC, et al (1995). Survival in breast cancer: A population-based study in Bangalore, India. Int J Cancer, 60, 593-6.
  16. National Cancer Registry Programme. Time Trends in Cancer Incidence Rates 1982-2005. Indian Council of Medical Research.
  17. Parkin DM, Bray F, Ferlay J, Pisani P (2001). Estimating the world cancer burden: Globocan 2000. Int J Cancer, 94, 153-6.
  18. Peto R, Boreham J, Clarke M, Davies C, Beral V (1996). UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years. Lancet, 355, 39.
  19. Stanley NC, Anyanwu OAE, Ihekwoaba EC (2011). Acceptance and adherence to treatment among breast cancer patients in Eastern Nigeria. The Breast, 20, S51-3.
  20. Sinha K, Ferlay J, et al (2000). GLOBOCAN: Cancer Incidence, Mortality, and PrevalenceWorldwide. Version 1.0. IARC Cancer Base No. 5. Lyon: IARC Press (2001).

Cited by

  1. Assessment of Biochemical Profiles in Premenopausal and Postmenopausal Women with Breast Cancer vol.13, pp.7, 2012,
  2. Breast Screening in North India: A Cost-Effective Cancer Prevention Strategy vol.14, pp.2, 2013,
  3. Overview of Cancer Registration Research in the Asian Pacific from 2008-2013 vol.14, pp.8, 2013,
  4. Illness Representations of Cancer among Healthy Residents of Kolkata, India vol.16, pp.2, 2015,
  5. In Vitro Evaluation of the Effects of Zearalenone and α-Zearalenol on MCF-7 and MDA-MB-468 Cell Lines of Human Breast Cancer vol.3, pp.4, 2015,