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Impacts of Fatigue, Pain, Anxiety, and Depression on the Quality of Life in Patients with Breast Cancer

유방암 환자의 피로, 통증, 불안, 우울이 삶의 질에 미치는 영향

  • 변혜선 (대구산업정보대학 간호과) ;
  • 김경덕 (동양대학교 간호학과)
  • Received : 2012.01.05
  • Accepted : 2012.02.05
  • Published : 2012.02.29

Abstract

Purpose: This study was conducted to identify the impact of fatigue, pain, anxiety and depression on the quality of life (QOL) among breast cancer patients. Methods: This study was conducted from July 12th to July 20th, 2010. One hundred and fifty breast cancer patients were recruited from D city in Korea. The instruments used in this study were the fatigue, pain, anxiety, depression and the quality of life scales for patients with breast cancer. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients and multiple regression with the SPSS/WIN 12.0 program. Results: The quality of life for cancer patients showed a significant relationship with fatigue, pain, anxiety and depression. The significant factors influencing quality of life were fatigue, pain, anxiety and depression that explained 65.6% of the variance. Conclusion: Patients with breast cancer experienced fatigue, pain, anxiety and depression which led to a negative effect on quality of life. The results suggest that intervention programs to reduce fatigue, pain, anxiety and depression could improve the quality of life for breast cancer patients.

References

  1. Brem S, Kumar NB. Management of treatment-related symptoms in patients with breast cancer: Current strategies and future directions. Clin J Oncol Nurs 2011;15:63-71. https://doi.org/10.1188/11.CJON.63-71
  2. Barsevick AM. The elusive concept of the symptom cluster. Oncol Nurs Forum 2007;34:971-80. https://doi.org/10.1188/07.ONF.971-980
  3. Kim SH, Lee R, Lee KS. Symtom clusters in patients with breast cancer. Korean J Adult Nurs 2009;21:705-17.
  4. Byar KL, Berger AM, Bakken SL, Cetak MA. Impact of adjuvant breast cancer chemotherapy on fatigue, other symptoms, and quality of life. Oncol Nurs Forum 2006;33:E18-26. https://doi.org/10.1188/06.ONF.E18-E26
  5. Dodd MJ, Cho MH, Cooper BA, Miaskowski C. The effect of symptom cluster on functional status and quality of life in women with breast cancer. Eur J Oncol Nurs 2010;14:101-10.
  6. Miaskowski C, Cooper BA, Paul SM, Dodd M, Lee K, Aouizerat BE, et al. Subgroups of patients with cancer with different symptom experiences and quality-of-life outcomes: A cluster analysis. Oncol Nurs Forum 2006;33:E79-89. https://doi.org/10.1188/06.ONF.E79-E89
  7. So WK, Marsh G, Ling WM, Leung FY, Lo JC, Yeung M, et al. The symptom cluster of fatigue, pain, anxiety, and depression and the effect on the quality of life of women receiving treatment for breast cancer: a multicenter study. Oncol Nurs Forum 2009;36:E205-14. https://doi.org/10.1188/09.ONF.E205-E214
  8. Suh YO. Predictors of quality of life in women with breast cancer. J Korean Acad Nurs 2007;37:459-66. https://doi.org/10.4040/jkan.2007.37.4.459
  9. Kim YS, Tae YS. The influencing factors on quality of life among breast cancer survivors. J Korean Oncol Nurs 2011;11:221-8. https://doi.org/10.5388/jkon.2011.11.3.221
  10. Park JH, Jun EY, Kang MY, Joung YS, Kim GS. Symptom experience and quality of life in breast cancer survivors. J Korean Acad Nurs 2009; 39:613-21. https://doi.org/10.4040/jkan.2009.39.5.613
  11. Pud D, Ben Ami S, Cooper BA, Aouizerat BE, Cohen D, Radiano R, et al. The symptom experience of oncology outpatients has a different impact on quality-of life outcomes. J Pain Symptom Manage 2008;35:162-70. https://doi.org/10.1016/j.jpainsymman.2007.03.010
  12. Bower JE, Ganz PA, Desmond KA, Bernaards C, Rowland JH, Meyerowitz BE, et al. Fatigue in long-term breast carcinoma survivors: a longitudinal investigation. Cancer 2006;106:751-8. https://doi.org/10.1002/cncr.21671
  13. Cavalli Kluthcovsky AC, Urbanetz AA, de Carvalho DS, Pereira Maluf EM, Schlickmann Sylvestre GC, Bonatto Hatschbach SB. Fatigue after treatment in breast cancer survivors: prevalence, determinants and impact on health-related quality of life. Support Care Cancer 2011;13:1293-7.
  14. Stevens PE, Dibble SL, Miaskowski C. Prevalence, characteristics, and impact of postmastectomy pain syndrome: an investigation of women's experience. Pain 1995;61:61-8. https://doi.org/10.1016/0304-3959(94)00162-8
  15. Chong MS, Bajwa ZH. Diagnosis and treatment of neuropathic pain. J Pain Symptom Manage 2003;25:S4-11. https://doi.org/10.1016/S0885-3924(03)00064-2
  16. Jung BF, Hermann D, Griggs J, Oaklander LA, Dworkin RH. Neuropathic pain associated with non-surgical treatment of breast cancer. Pain 2005;118:10-4. https://doi.org/10.1016/j.pain.2005.09.014
  17. Fann JR, Thomas-Rich AM, Katon WJ, Cowley D, Pepping M, Mcgregor BA, et al. Major depression after breast cancer: a review of epidemiology and treatment. Gen Hosp Psychiatry 2008;30:112-26. https://doi.org/10.1016/j.genhosppsych.2007.10.008
  18. Reyes-Gibby CC, Anderson KO, Morrow PK, Shete S, Hassan S. Depressive symptoms and health-related quality of life in breast survivors. J Womens Health 2012;21:1-8. https://doi.org/10.1089/jwh.2011.3263
  19. van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, Schouten HC, van Kleef M, Pantijin J. Quality of life and non-pain symptoms in patients with cancer. J pain Symptom Manage 2009;38:216-33. https://doi.org/10.1016/j.jpainsymman.2008.08.014
  20. Burgess C, Cornelius V, Love S, Graham J, Richards M, Ramirez A. Depression and anxiety in women with early breast cancer: Five year observational cohort study. BMJ 2005;330:702-5. https://doi.org/10.1136/bmj.38343.670868.D3
  21. Functional Assessment of Chronic Illness Therapy. FACIT-Fatigue scale-Korean version. Availble at://www.facit.org/FACITOrg/Questionnaires [accessed on 1 June 2010].
  22. Kim JT, Shin DK. A study based on the standardization of the STAI for Korea. J New Med 1978;21:69-75.
  23. Chon KK, Lee MK. Preliminary development of Korean version of CES-D. Korean J Clini Psychol 1992;11:65-76.
  24. Functional Assessment of Chronic Illness Therapy. Functional assessment of cancer therapy-breast cancer version 4-Korean version. Availble at //www. facit.org /FACITOrg/Questionnaires [accessed on 1 June 2010].
  25. Kim GD, Kim KH. Symptom cluster and quality of life with breast cancer undergoing chemotherapy. Korean J Adult Nurs 2011;23:434-45.
  26. Byun HS, Kim GD, Chung BY, Kim KH. Fatigue and quality of life of Korean cancer inpatients. J Hospice Palliative Care 2010;13:98-108.
  27. Stevens PE, Dibble SL, Miaskowski C. Prevalence, characteristics, and impact of postmastectomy pain syndrome: an investigation of women's experience. Pain 1995;61:61-8. https://doi.org/10.1016/0304-3959(94)00162-8
  28. Chong SM, Bajwa ZH. Diagnosis and treatment of neuropathic pain. J Pain Symptom Manage 2003;25(5):S4-11. https://doi.org/10.1016/S0885-3924(03)00064-2
  29. Yoo MS, Lee HJ, Yoon JA. Effects of a cognitive behavioral nursing intervention on anxiety and depression in women with breast cancer undergoing radiography. J Korean Acad Nurs 2009;39:157-65. https://doi.org/10.4040/jkan.2009.39.2.157
  30. Beck SL, Dudley WN, Barsevick A. Pain, sleep, disturbance, and fatigue in patients with cancer: using a mediation model to test a symptom cluster. Oncol Nurs Forum 2005;32:E48-55. https://doi.org/10.1188/05.ONF.E48-E55