- Volume 12 Issue 1
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Cognitive Function in Breast Cancer Patients Receiving Adjuvant Chemotherapy
항암화학요법을 받은 유방암 환자의 인지기능
- Kim, Kyung-Hae (Department of Nursing, Kimcheon Science College) ;
- Chung, Bok-Yae (School of Nursing, Kyungpook National University) ;
- Kim, Gyung-Duck (Department of Nursing, Dongyang University) ;
- Byun, Hye-Sun (Department of Nursing, Daegu Polytechnic College) ;
- Choi, Eun-Hee (Department of Nursing, Yeungnam College of Science and Technology) ;
- Cho, Eun-Jung (Department of Nursing, Sorabol College)
- 김경혜 (김천과학대학 간호과) ;
- 정복례 (경북대학교 간호대학) ;
- 김경덕 (동양대학교 간호학과) ;
- 변혜선 (대구산업정보대학 간호과) ;
- 최은희 (영남이공대학 간호과) ;
- 조은정 (서라벌대학 간호과)
- Received : 2012.01.05
- Accepted : 2012.02.05
- Published : 2012.02.29
Purpose: This study reviewed articles related to breast cancer, cognitive function and chemotherapy available in 4 databases. Methods: The researcher reviewed 32 pieces of literature that were published between January 2001 and November 2011. Results: Within the last decade, several studies have investigated whether adjuvant treatment of breast cancer affects cognitive function. A number of prospective studies have reported inconsistent results regarding whether chemotherapy affects cognitive function. Approximately half of the studies reported subtle cognitive decline in a wide range of domains among some breast cancer patients following chemotherapy, and others did not. Conclusion: Breast cancer patients receiving adjuvant chemotherapy showed the most deterioration and the most persistent decline in cognitive function. Since cognitive impairment is subtle, if evident at all, discrepant findings are due to hormonal, physiological, psychological or temporal confounding variables and differences in study design. Especially, that chemotherapy may impair memory, executive function, attention and visuospatial function in women with breast cancer.
Supported by : 한국연구재단
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