Parental Knowledge and Attitudes about Human Papilloma Virus in Iran

  • Ghojazadeh, Morteza (Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences) ;
  • Naghavi-Behzad, Mohammad (Medical Philosophy and History Research Center, Tabriz University of Medical Sciences) ;
  • Azar, Zahra Fardi (Department of Gynecology and Obstetrics, Medical Faculty, Tabriz University of Medical Sciences) ;
  • Saleh, Parviz (Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences) ;
  • Ghorashi, Sona (Young Researchers Club, Tabriz Branch, Islamic Azad University) ;
  • Pouri, Ali-Asghar (Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences)
  • 발행 : 2012.12.31


Infection by human papillomavirus (HPV) is one of common sexually transmitted diseases leading to cervical cancer. Evaluation of parental knowledge and attitudes toward HPV were aims of present study to provide an appropriate method to decrease burden of this infection on society. During this study, 358 parents were assessed for knowledge about HPV and its related disorders. Some 76% of parents had no information about HPV infection and among the informed parents 36% had obtained their information via internet and others from studying medical resources. The average score of mothers information about HPV infection was higher than that of fathers, and also educational level and age had significant impact on knowledge of parents about HPV. Parent knowledge about the hazards of HPV was higher than their knowledge about modes of transmission. Lack of awareness about HPV infection was high in this study, underlining the urgency of education among all adult people in our society.


  1. Aldrich T, D. Becker, et al. (2005). "Mexican physicians'knowledge and attitudes about the human papillomavirus and cervical cancer: a national survey." Sex Transm Infect 81(2): 135-141.
  2. Brisson, M. and W. J. Edmunds (2003). "Economic evaluation of vaccination programs: the impact of herd-immunity." Med Decis Making 23(1): 76-82.
  3. Conaglen, H. M., R. Hughes, et al. (2001). "A prospective study of the psychological impact on patients of first diagnosis of human papillomavirus." Int J STD AIDS 12(10): 651-658.
  4. D'Souza, G., R. D. Burk, et al. (2012). "Cervicovaginal human papillomavirus (HPV)-infection before and after hysterectomy: evidence of different tissue tropism for oncogenic and nononcogenic HPV types in a cohort of HIVpositive and HIV-negative women." Int J Cancer 131(6):1472-1478.
  5. Dasbach, E. J., E. H. Elbasha, et al. (2006). "Mathematical models for predicting the epidemiologic and economic impact of vaccination against human papillomavirus infection and disease." Epidemiol Rev 28: 88-100.
  6. Dell, D. L., H. Chen, et al. (2000). "Knowledge about human papillomavirus among adolescents." Obstet Gynecol 96(5 Pt 1): 653-656.
  7. Dunne, E. F., E. R. Unger, et al. (2007). "Prevalence of HPV infection among females in the United States." JAMA 297(8): 813-819.
  8. Eltoum, I. A. and J. Roberson (2007). "Impact of HPV testing, HPV vaccine development, and changing screening frequency on national Pap test volume: projections from the National Health Interview Survey (NHIS)." Cancer 111(1): 34-40.
  9. Francis, S. A., J. Nelson, et al. (2010). "Examining attitudes and knowledge about HPV and cervical cancer risk among female clinic attendees in Johannesburg, South Africa." Vaccine 28(50): 8026-8032.
  10. Ghotbi, N. and A. Anai (2012). "Assessment of the knowledge and attitude of female students towards cervical cancer prevention at an international university in Japan." Asian Pac J Cancer Prev 13(3): 897-900.
  11. Ho, G. Y., R. Bierman, et al. (1998). "Natural history of cervicovaginal papillomavirus infection in young women." N Engl J Med 338(7): 423-428.
  12. Insinga, R. P., A. G. Glass, et al. (2004). "The health care costs of cervical human papillomavirus--related disease." Am J Obstet Gynecol 191(1): 114-120.
  13. Johnson, A. M., C. H. Mercer, et al. (2012). "Epidemiology of, and behavioural risk factors for, sexually transmitted human papillomavirus infection in men and women in Britain." Sex Transm Infect 88(3): 212-217.
  14. Klug, S. J., M. Hukelmann, et al. (2008). "Knowledge about infection with human papillomavirus: a systematic review." Prev Med 46(2): 87-98.
  15. Lacey, C. J., C. M. Lowndes, et al. (2006). "Chapter 4: Burden and management of non-cancerous HPV-related conditions: HPV-6/11 disease." Vaccine 24 Suppl 3: S3/35-41.
  16. Lenselink, C. H., C. E. Schmeink, et al. (2008). "Young adults and acceptance of the human papillomavirus vaccine." Public Health 122(12): 1295-1301.
  17. Li, J., L. K. Li, et al. (2009). "Knowledge and attitudes about human papillomavirus (HPV) and HPV vaccines among women living in metropolitan and rural regions of China." Vaccine 27(8): 1210-1215.
  18. Mahdavi, A. and B. J. Monk (2005). "Vaccines against human papillomavirus and cervical cancer: promises and challenges." Oncologist 10(7): 528-538.
  19. Merchant, R. C. (2006). "Update on emerging infections: news from the Centers for Disease Control and Prevention. Updated U.S. Public Health Service guidelines for the management of occupational exposures of HIV and recommendations for postexposure prophylaxis." Ann Emerg Med 47(5): 492-495.
  20. Merzouk, M. D., P. Courtney, et al. (2011). "Knowledge of HPV in West Virginia high school health students and the effects of an educational tool." J Pediatr Adolesc Gynecol 24(5): 278-281.
  21. Nadji, S. A., T. Mokhtari-Azad, et al. (2007). "Relationship between lung cancer and human papillomavirus in north of Iran, Mazandaran province." Cancer Lett 248(1): 41-46.
  22. Nash, D., S. Azeez, et al. (2006). "Evaluation of an intervention to increase screening colonoscopy in an urban public hospital setting." J Urban Health 83(2): 231-243.
  23. Parkin, D. M. and F. Bray (2006). "Chapter 2: The burden of HPV-related cancers." Vaccine 24 Suppl 3: S3/11-25.
  24. Parkin, D. M., F. Bray, et al. (2001). "Estimating the world cancer burden: Globocan 2000." Int J Cancer 94(2): 153-156.
  25. Philips, Z., S. Johnson, et al. (2003). "Human papillomavirus and the value of screening: young women's knowledge of cervical cancer." Health Educ Res 18(3): 318-328.
  26. Ragin, C. C., R. P. Edwards, et al. (2009). "Knowledge about human papillomavirus and the HPV vaccine--a survey of the general population." Infect Agent Cancer 4 Suppl 1: S10.
  27. Ramachandran, S. and Y. F. Ngeow (1990). "The prevalence of sexually transmitted diseases among prostitutes in Malaysia." Genitourin Med 66(5): 334-336.
  28. Rashwan, H. H., N. Z. Saat, et al. (2012). "Knowledge, attitude and practice of malaysian medical and pharmacy students towards human papillomavirus vaccination." Asian Pac J Cancer Prev 13(5): 2279-2283.
  29. Riegelman, R. K. and D. R. Garr (2011). "Healthy People 2020 and Education for Health: what are the objectives?" Am J Prev Med 40(2): 203-206.
  30. Safaei, A., M. Khanlari, et al. (2010). "Prevalence of high-risk human papillomavirus types 16 and 18 in healthy women with cytologically negative pap smear in Iran." Indian J Pathol Microbiol 53(4): 681-685.
  31. Smith, J. S., A. Melendy, et al. (2008). "Age-specific prevalence of infection with human papillomavirus in females: a global review." J Adolesc Health 43(4 Suppl): S5-25, S25 e21-41.
  32. Vail-Smith, K. and D. M. White (1992). "Risk level, knowledge, and preventive behavior for human papillomaviruses among sexually active college women." J Am Coll Health 40(5):227-230.
  33. Villar, L. M., A. D. Rabello, et al. (2011). "Evaluating knowledge about human papillomavirus infection among Brazilian health professionals." Asian Pac J Cancer Prev 12(12):3251-3256.
  34. Watson, M., M. Saraiya, et al. (2008). "Burden of cervical cancer in the United States, 1998-2003." Cancer 113(10 Suppl): 2855-2864.
  35. Wendell, D. A., D. A. Cohen, et al. (2003). "Street outreach for HIV prevention: effectiveness of a state-wide programme." Int J STD AIDS 14(5): 334-340.
  36. Yacobi, E., C. Tennant, et al. (1999). "University students' knowledge and awareness of HPV." Prev Med 28(6): 535-541.
  37. Zandi, K., S. S. Eghbali, et al. (2010). "Prevalence of various human papillomavirus (HPV) genotypes among women who subjected to routine Pap smear test in Bushehr city (south west of Iran) 2008-2009." Virol J 7: 65.
  38. Zhao, F. H., S. M. Tiggelaar, et al. (2012). "A multi-center survey of HPV knowledge and attitudes toward HPV vaccination among women, government officials, and medical personnel in China." Asian Pac J Cancer Prev 13(5): 2369-2378.
  39. Zou, L., Y. P. Bao, et al. (2011). "Life-style and genital human papillomavirus in a cross-sectional survey in Shanxi Province, China." Asian Pac J Cancer Prev 12(3): 781-786.

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