- Volume 13 Issue 12
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Screening for in vitro Cytotoxic Activity of Seaweed, Sargassum sp. Against Hep-2 and MCF-7 Cancer Cell Lines
- Mary, J. Stella (Post Graduate Department of Immunology and Microbiology, The American College) ;
- Vinotha, P. (Post Graduate Department of Immunology and Microbiology, The American College) ;
- Pradeep, Andrew M. (Post Graduate Department of Immunology and Microbiology, The American College)
- Published : 2012.12.31
Discovery of anticancer drugs that kill or disable tumor cells in the presence of normal cells without undue toxicity is a potential challenge for therapeutic care. Several papers in the literature have emphasized the potential implications of marine products such as seaweeds which exhibit antitumor activity. Study attempts to screen the antitumor effect of Sargassum sp, against chosen cell lines such as MCF-7 (Breast cancer) and Hep-2 (Liver Cancer). Ethanol extract of Sargassum sp. was concentrated using a Soxhlet apparatus and dissolved in DMSO. In vitro cytotoxic activity of Sargassum sp at various concentrations (
MTT;Sargassum sp.;apoptosis;HEP 2;MCF 7
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