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Clinicopathological Profile of Head and Neck Cancers in the Western Development Region, Nepal: A 4-Year Snapshot

  • Lasrado, Savita (Department of Otorhinolaryngology and Head and Neck Surgery, Father Muller Medical College) ;
  • Prabhu, Prashanth (Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College) ;
  • Kakria, Anjali (Department of Radiotherapy and Oncology, Kasturba Medical College) ;
  • Kanchan, Tanuj (Department of Forensic Medicine and Toxicology, Kasturba Medical College (Affiliated to Manipal University)) ;
  • Pant, Sadip (Department of Internal Medicine, University of Arkansas for Medical Sciences) ;
  • Sathian, Brijesh (Department of Community Medicine, Manipal College of Medical Sciences) ;
  • Gangadharan, P. (Cancer Registry, Amrita Institute of Medical Sciences and Research Centre) ;
  • Binu, V.S. (Department of Statistics, Manipal University) ;
  • Arathisenthil, S.V. (Department of Oral Pathology and Microbiology, Priyadarshini Dental College and Hospital) ;
  • Jeergal, Prabhakar A. (Department of Oral and Maxillofacial Pathology, AJ Institute of Dental Sciences) ;
  • Luis, Neil A. (Dental Surgeon in Private Practice) ;
  • Menezes, Ritesh G. (Department of Forensic Medicine and Toxicology, Srinivas Institute of Medical Sciences)
  • Published : 2012.12.31

Abstract

Regional cancer epidemiology is an important basis for determining the priorities for cancer control in different countries worldwide. There is no reliable information about the pattern of head and neck cancer in western Nepal and hence an attempt was here made to evaluate the situation based on hospital data, which provide the only source in the western region of Nepal. A clinicopathological analysis of head and neck cancers treated between 2003 and 2006 in Manipal Teaching Hospital affiliated to Manipal College of Medical Sciences, Pokhara, Western Development Region, Nepal was performed. A total of 105 head and neck cancer cases were identified with a male to female ratio of 1.8:1. The median ages of male and female patients were 62 and 64 years, respectively. Ninety-seven (92.4%) of the cancer patients were suffering from carcinoma, three (2.9%) had blastoma, three (2.9%) had sarcoma, and two (1.9%) had lymphoma. The majority (61.9%) of carcinoma cases were squamous cell carcinoma followed by anaplastic carcinoma (7.2%). Of the carcinoma cases, the most common site of primary lesion was larynx (19.6%), followed by the thyroid (14.4%), the tongue and hypopharynx with 10.3% cases each. Comparative analysis among males and females did not reveal any sex difference in type of head and neck cancers. The head and neck cancer pattern revealed by the present study provides valuable leads to cancer epidemiology in western Nepal and useful information for health planning and cancer control, and future research in western Nepal.

Keywords

Head and neck cancer;squamous cell carcinoma;clinicopathological profile;Nepal

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